Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RUFY3	22902	broad.mit.edu	37	4	71634293	71634293	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr4:71634293A>G	ENST00000226328.4	+	5	1174	c.611A>G	c.(610-612)gAa>gGa	p.E204G	RUFY3_ENST00000502653.1_Missense_Mutation_p.E151G|RUFY3_ENST00000381006.3_Missense_Mutation_p.E204G|RUFY3_ENST00000536664.1_Missense_Mutation_p.E188G|RUFY3_ENST00000417478.2_Missense_Mutation_p.E264G	NM_014961.3	NP_055776.1	Q7L099	RUFY3_HUMAN	RUN and FYVE domain containing 3	204	RUN.				negative regulation of axonogenesis	filopodium|growth cone				endometrium(1)|kidney(3)|large_intestine(4)|lung(6)|prostate(1)|stomach(1)	16		all_hematologic(202;0.248)	Lung(101;0.235)			ATGGAAGAAGAAGGAGCCATA	0.413000													51	67					0	0	1	0	0
TBC1D10B	26000	broad.mit.edu	37	16	30369824	30369824	+	Missense_Mutation	SNP	T	T	C			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr16:30369824T>C	ENST00000409939.3	-	9	1948	c.1868A>G	c.(1867-1869)gAa>gGa	p.E623G		NM_015527.3	NP_056342.3	Q4KMP7	TB10B_HUMAN	TBC1 domain family, member 10B	623						cytoplasm	Rab GTPase activator activity			endometrium(2)|kidney(1)|lung(2)|urinary_tract(1)	6			Colorectal(24;0.193)			CCCCCGCGTTTCCCGCCACTT	0.647000													8	2					0	0	1	0	0
EYS	346007	broad.mit.edu	37	6	66204999	66204999	+	Missense_Mutation	SNP	T	T	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr6:66204999T>A	ENST00000503581.1	-	4	842	c.305A>T	c.(304-306)aAt>aTt	p.N102I	EYS_ENST00000393380.2_Missense_Mutation_p.N102I|EYS_ENST00000370616.2_Missense_Mutation_p.N102I|EYS_ENST00000370621.3_Missense_Mutation_p.N102I|EYS_ENST00000342421.5_Missense_Mutation_p.N102I|EYS_ENST00000370618.3_Missense_Mutation_p.N102I	NM_001142800.1	NP_001136272.1	Q5T1H1	EYS_HUMAN	eyes shut homolog (Drosophila)	102					response to stimulus|visual perception	extracellular region	calcium ion binding			breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(12)|lung(42)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(3)	69						ATTCATCAAATTTATTTCTGG	0.378000													8	51					0	0	1	0	0
RALGAPB	57148	broad.mit.edu	37	20	37179720	37179720	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr20:37179720G>A	ENST00000262879.6	+	21	3300	c.3016G>A	c.(3016-3018)Gta>Ata	p.V1006I	RALGAPB_ENST00000397040.1_Missense_Mutation_p.V1006I|RALGAPB_ENST00000397042.3_Missense_Mutation_p.V1002I|RALGAPB_ENST00000397038.1_Missense_Mutation_p.V784I			Q86X10	RLGPB_HUMAN	Ral GTPase activating protein, beta subunit (non-catalytic)	1006					activation of Ral GTPase activity	intracellular	protein heterodimerization activity|Ral GTPase activator activity			breast(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(8)|lung(29)|ovary(1)|pancreas(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(2)	65						ACAGCTTTTTGTACCTGAACC	0.388000													5	153					0	0	1	0	0
ZBTB47	92999	broad.mit.edu	37	3	42703080	42703080	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr3:42703080A>G	ENST00000457842.3	+	3	1858	c.449A>G	c.(448-450)gAg>gGg	p.E150G	ZBTB47_ENST00000232974.6_Missense_Mutation_p.E526G|ZBTB47_ENST00000505904.1_Missense_Mutation_p.E72G	NM_145166.3	NP_660149.2	Q9UFB7	ZBT47_HUMAN	zinc finger and BTB domain containing 47	150					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			autonomic_ganglia(1)|breast(2)|endometrium(4)|large_intestine(2)|lung(3)|ovary(1)	13				KIRC - Kidney renal clear cell carcinoma(284;0.216)		GAGATCTGTGAGAAGAAGTTC	0.517000													3	31					0	0	1	0	0
PPP1R14D	54866	broad.mit.edu	37	15	41120792	41120792	+	Silent	SNP	C	C	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr15:41120792C>A	ENST00000299174.5	-	1	115	c.48G>T	c.(46-48)ggG>ggT	p.G16G	PPP1R14D_ENST00000427255.2_Silent_p.G16G	NM_017726.7	NP_060196.1	Q9NXH3	PP14D_HUMAN	protein phosphatase 1, regulatory (inhibitor) subunit 14D	16					regulation of phosphorylation	cytoplasm	protein phosphatase inhibitor activity			breast(1)|large_intestine(2)|lung(2)|skin(1)	6		all_cancers(109;6.29e-14)|all_epithelial(112;1.48e-11)|Lung NSC(122;5.77e-09)|all_lung(180;1.08e-07)|Melanoma(134;0.091)|Colorectal(260;0.175)|Ovarian(310;0.243)		GBM - Glioblastoma multiforme(113;2.88e-05)|COAD - Colon adenocarcinoma(120;0.153)|BRCA - Breast invasive adenocarcinoma(123;0.166)		ATGGGTTCTCCCCATCTGGGC	0.557000													9	34					1.76689e-08	1.82044e-08	1	1	0
ZNF80	7634	broad.mit.edu	37	3	113955352	113955352	+	Silent	SNP	C	C	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr3:113955352C>T	ENST00000482457.2	-	1	1073	c.570G>A	c.(568-570)aaG>aaA	p.K190K		NM_007136.3	NP_009067.2	P51504	ZNF80_HUMAN	zinc finger protein 80	190						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(1)|endometrium(1)|large_intestine(9)|lung(15)|ovary(2)|prostate(2)|urinary_tract(2)	32		Lung NSC(201;0.0233)|all_neural(597;0.0837)				ACTCACTGCACTTGCAGGGCT	0.478000													47	75					0	0	1	0	0
FAM49A	81553	broad.mit.edu	37	2	16734239	16734239	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr2:16734239A>G	ENST00000381323.3	-	12	1157	c.937T>C	c.(937-939)Tca>Cca	p.S313P	FAM49A_ENST00000406434.1_Missense_Mutation_p.S313P|FAM49A_ENST00000355549.2_Missense_Mutation_p.S313P	NM_030797.3	NP_110424.1	Q9H0Q0	FA49A_HUMAN	family with sequence similarity 49, member A	313						intracellular				breast(1)|central_nervous_system(1)|kidney(1)|large_intestine(4)|liver(1)|lung(11)|skin(3)|upper_aerodigestive_tract(1)	23	Acute lymphoblastic leukemia(172;0.0734)|all_hematologic(175;0.088)		GBM - Glioblastoma multiforme(3;0.00969)			TTGGAAGTTGATTCATCGTTC	0.418000													31	34					0	0	1	0	0
BMS1P20	96610	broad.mit.edu	37	22	22664186	22664186	+	RNA	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr22:22664186A>G	ENST00000426066.1	+	0	709					NR_027293.1																						CAGATCAAGAAAGCACTCTGA	0.498000													3	42					0	0	1	0	0
AKAP9	10142	broad.mit.edu	37	7	91715671	91715671	+	Missense_Mutation	SNP	C	C	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr7:91715671C>G	ENST00000359028.2	+	37	9391	c.9166C>G	c.(9166-9168)Cta>Gta	p.L3056V	AKAP9_ENST00000356239.3_Missense_Mutation_p.L3052V|AKAP9_ENST00000358100.2_Missense_Mutation_p.L3002V			Q99996	AKAP9_HUMAN	A kinase (PRKA) anchor protein 9	3056					G2/M transition of mitotic cell cycle|signal transduction|synaptic transmission|transport	centrosome|cytosol|Golgi apparatus	receptor binding			NS(1)|autonomic_ganglia(2)|breast(14)|central_nervous_system(3)|cervix(1)|endometrium(13)|kidney(12)|large_intestine(35)|lung(49)|ovary(8)|prostate(6)|skin(8)|stomach(1)|urinary_tract(2)	155	all_cancers(62;2.46e-09)|all_epithelial(64;4.42e-08)|Breast(17;0.00206)|all_lung(186;0.185)|all_hematologic(106;0.215)|Lung NSC(181;0.249)		STAD - Stomach adenocarcinoma(171;6.16e-05)|Lung(22;0.123)|LUSC - Lung squamous cell carcinoma(200;0.225)			GCTGACAGCTCTAGGTACTAC	0.388000			T	BRAF	papillary thyroid								8	195					0	0	1	0	0
B4GALNT4	338707	broad.mit.edu	37	11	375706	375706	+	Silent	SNP	G	G	C			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr11:375706G>C	ENST00000329962.6	+	10	918	c.918G>C	c.(916-918)ggG>ggC	p.G306G		NM_178537.4	NP_848632.2	Q76KP1	B4GN4_HUMAN	beta-1,4-N-acetyl-galactosaminyl transferase 4	306						Golgi cisterna membrane|integral to membrane	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity			endometrium(2)|kidney(4)|large_intestine(1)|liver(2)|lung(7)|ovary(2)|pancreas(1)|prostate(4)|upper_aerodigestive_tract(1)	24		all_cancers(49;1.59e-06)|all_epithelial(84;0.000256)|Breast(177;0.00122)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		all cancers(45;1.56e-27)|Epithelial(43;9.31e-27)|OV - Ovarian serous cystadenocarcinoma(40;1.11e-20)|BRCA - Breast invasive adenocarcinoma(625;3.56e-05)|Lung(200;0.0182)|LUSC - Lung squamous cell carcinoma(625;0.0703)		ACGTGGGGGGGCGTCCGCCGC	0.677000													6	27					0	0	1	0	0
MINK1	50488	broad.mit.edu	37	17	4788820	4788820	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr17:4788820G>A	ENST00000355280.6	+	7	747	c.551G>A	c.(550-552)aGa>aAa	p.R184K	MINK1_ENST00000453408.3_Missense_Mutation_p.R184K|MINK1_ENST00000347992.7_Missense_Mutation_p.R184K	NM_001024937.3|NM_015716.4|NM_153827.4	NP_001020108.1|NP_056531.1|NP_722549.2	Q8N4C8	MINK1_HUMAN	misshapen-like kinase 1	184	Protein kinase.				JNK cascade	cytoplasm	ATP binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			central_nervous_system(2)|large_intestine(1)|lung(1)|skin(1)|stomach(1)	6						ACCGTGGGCAGACGGAACACT	0.567000													29	58					0	0	1	0	0
ADAMTS10	81794	broad.mit.edu	37	19	8654799	8654799	+	Missense_Mutation	SNP	A	A	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr19:8654799A>T	ENST00000270328.4	-	15	2140	c.1874T>A	c.(1873-1875)tTc>tAc	p.F625Y	ADAMTS10_ENST00000597188.1_Missense_Mutation_p.F625Y|ADAMTS10_ENST00000595838.1_Missense_Mutation_p.S116T			Q9H324	ATS10_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 10	625	Cys-rich.				proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(2)|kidney(16)|large_intestine(5)|lung(9)|ovary(1)|pancreas(2)|prostate(3)|skin(10)|urinary_tract(1)	53						CCACTTGTAGAATTTCCCACG	0.577000													31	33					0	0	1	0	0
MCPH1	79648	broad.mit.edu	37	8	6264189	6264189	+	Translation_Start_Site	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr8:6264189A>G	ENST00000344683.5	+	1	77	c.1A>G	c.(1-3)Atg>Gtg	p.M1V	MCPH1_ENST00000522905.1_Start_Codon_SNP_p.M1V|MCPH1_ENST00000519480.1_Start_Codon_SNP_p.M1V|RP11-115C21.2_ENST00000523225.1_RNA	NM_024596.3	NP_078872.2	Q8NEM0	MCPH1_HUMAN	microcephalin 1	1	BRCT 1.					microtubule organizing center			AGPAT5/MCPH1(2)	central_nervous_system(1)|large_intestine(4)|skin(1)	6		Hepatocellular(245;0.0663)		Colorectal(4;0.0505)		GCCGTCTGTCATGGCGGCCCC	0.726000													3	3					0	0	1	0	0
RBM38	55544	broad.mit.edu	37	20	55982660	55982660	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr20:55982660G>A	ENST00000356208.5	+	4	653	c.478G>A	c.(478-480)Gcc>Acc	p.A160T	RBM38_ENST00000371219.2_Missense_Mutation_p.A79T|RBM38_ENST00000440234.2_3'UTR	NM_017495.5	NP_059965.2	Q9H0Z9	RBM38_HUMAN	RNA binding motif protein 38	160					3'-UTR-mediated mRNA stabilization|cell cycle|cell cycle arrest|cell differentiation|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|mRNA processing|negative regulation of cell proliferation|regulation of RNA splicing|RNA splicing	cytosol|nucleus	mRNA 3'-UTR binding|mRNA binding|nucleotide binding|RNA binding			large_intestine(3)|lung(3)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	9	Lung NSC(12;0.00242)|all_lung(29;0.00767)|Melanoma(10;0.242)		BRCA - Breast invasive adenocarcinoma(4;1.55e-12)|Epithelial(14;9.49e-09)|all cancers(14;5.01e-08)			GATCCCAGCCGCCCCTGTCCC	0.662000													3	32					0	0	1	0	0
KRT72	140807	broad.mit.edu	37	12	52981542	52981542	+	Missense_Mutation	SNP	C	C	T	rs145882334	byFrequency	TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr12:52981542C>T	ENST00000293745.2	-	7	1268	c.1183G>A	c.(1183-1185)Gcc>Acc	p.A395T	KRT72_ENST00000537672.2_Missense_Mutation_p.A395T|KRT72_ENST00000354310.4_Missense_Mutation_p.A353T|KRT72_ENST00000398066.3_Missense_Mutation_p.A207T	NM_080747.2	NP_542785.1	Q14CN4	K2C72_HUMAN	keratin 72	395	Coil 2.|Rod.					keratin filament	structural molecule activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(6)|lung(14)|ovary(5)|pancreas(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(2)	36				BRCA - Breast invasive adenocarcinoma(357;0.195)		TGGTGCAGGGCGCCCTCCAGC	0.662000													37	50					0	0	1	0	0
EMC9	51016	broad.mit.edu	37	14	24610468	24610468	+	Silent	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr14:24610468G>A	ENST00000419198.2	-	1	326	c.46C>T	c.(46-48)Ctg>Ttg	p.L16L	EMC9_ENST00000560403.1_Intron|EMC9_ENST00000558200.1_5'UTR|EMC9_ENST00000216799.4_Silent_p.L16L					ER membrane protein complex subunit 9																		GCAGCATGCAGGCACATCTTC	0.647000											OREG0022618	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	20	40					0	0	1	0	0
ZFP41	286128	broad.mit.edu	37	8	144332586	144332586	+	Silent	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr8:144332586A>G	ENST00000330701.4	+	2	942	c.573A>G	c.(571-573)aaA>aaG	p.K191K	ZFP41_ENST00000522452.1_Silent_p.K191K|ZFP41_ENST00000520584.1_Silent_p.K191K	NM_173832.3	NP_776193.1	Q8N8Y5	ZFP41_HUMAN	ZFP41 zinc finger protein	191					cell differentiation|multicellular organismal development|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(2)|lung(4)|ovary(1)	8	all_cancers(97;1.01e-10)|all_epithelial(106;4.6e-09)|Lung NSC(106;0.000167)|all_lung(105;0.000459)|Ovarian(258;0.0212)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.156)|Colorectal(110;0.173)			GCCATCAGAAACGCCACCCTC	0.642000													12	75					0	0	1	0	0
GUSBP1	728411	broad.mit.edu	37	5	21497235	21497235	+	RNA	SNP	C	C	T	rs141635554	by1000genomes	TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr5:21497235C>T	ENST00000607545.1	+	0	179					NR_027026.1																						AGTTTGAGAACTGGTGTAAGA	0.488000													3	49					0	0	1	0	0
ACSM2B	348158	broad.mit.edu	37	16	20565160	20565160	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr16:20565160G>A	ENST00000329697.6	-	5	847	c.679C>T	c.(679-681)Ctt>Ttt	p.L227F	ACSM2B_ENST00000567001.1_Missense_Mutation_p.L227F|ACSM2B_ENST00000565232.1_Missense_Mutation_p.L227F|ACSM2B_ENST00000565322.1_Missense_Mutation_p.L148F	NM_001105069.1	NP_001098539.1	Q68CK6	ACS2B_HUMAN	acyl-CoA synthetase medium-chain family member 2B	227					fatty acid metabolic process|xenobiotic metabolic process	mitochondrial matrix	ATP binding|butyrate-CoA ligase activity|CoA-ligase activity|metal ion binding			breast(4)|central_nervous_system(2)|endometrium(5)|kidney(2)|large_intestine(4)|lung(33)|ovary(1)|prostate(1)|skin(5)	57						ATCTTGGGAAGACCACTGGTC	0.512000													11	27					0	0	1	0	0
CCDC64B	146439	broad.mit.edu	37	16	3085362	3085362	+	Missense_Mutation	SNP	C	C	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr16:3085362C>G	ENST00000572449.1	-	2	198	c.136G>C	c.(136-138)Gag>Cag	p.E46Q	RP11-473M20.5_ENST00000382225.3_RNA|CCDC64B_ENST00000389347.4_Missense_Mutation_p.E46Q			A1A5D9	BICR2_HUMAN	coiled-coil domain containing 64B	46										breast(1)|endometrium(2)|large_intestine(1)	4						TCCTCGGGCTCCTCAGGCCCT	0.662000													6	3					0	0	1	0	0
BMS1P20	96610	broad.mit.edu	37	22	22663086	22663086	+	RNA	SNP	T	T	G	rs1054157	by1000genomes	TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr22:22663086T>G	ENST00000426066.1	+	0	525					NR_027293.1																						AGCTGCCACATAAGTTGTCCT	0.299000													9	2					0	0	1	0	0
TUBGCP6	85378	broad.mit.edu	37	22	50657281	50657281	+	Missense_Mutation	SNP	G	G	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr22:50657281G>T	ENST00000248846.5	-	21	4776	c.4672C>A	c.(4672-4674)Ctg>Atg	p.L1558M	TUBGCP6_ENST00000439308.2_3'UTR|TUBGCP6_ENST00000491449.1_5'UTR			Q96RT7	GCP6_HUMAN	tubulin, gamma complex associated protein 6	1558					G2/M transition of mitotic cell cycle|microtubule nucleation	centrosome|cytosol|gamma-tubulin ring complex|microtubule|spindle pole	microtubule binding			breast(4)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(13)|ovary(3)|prostate(2)|skin(2)	45		all_cancers(38;5.79e-13)|all_epithelial(38;1.71e-11)|all_lung(38;3.89e-05)|Breast(42;0.000523)|Lung NSC(38;0.000992)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		LUAD - Lung adenocarcinoma(64;0.109)|BRCA - Breast invasive adenocarcinoma(115;0.21)		ACAGAGTTCAGCACCAGCGGG	0.637000													15	7					9.7654e-05	9.7654e-05	1	1	0
INSRR	3645	broad.mit.edu	37	1	156816315	156816315	+	Silent	SNP	A	A	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr1:156816315A>T	ENST00000368195.3	-	8	2202	c.1806T>A	c.(1804-1806)ccT>ccA	p.P602P	NTRK1_ENST00000392302.2_Intron	NM_014215.2	NP_055030.1	P14616	INSRR_HUMAN	insulin receptor-related receptor	602					protein autophosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	ATP binding|insulin receptor substrate binding|metal ion binding|phosphatidylinositol 3-kinase binding|transmembrane receptor protein tyrosine kinase activity			breast(1)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(8)|lung(13)|ovary(7)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)	42	all_hematologic(923;0.0839)|Hepatocellular(266;0.158)					GCCTACCTGCAGGCAGCGTTC	0.582000													6	4					0	0	1	0	0
STON1	11037	broad.mit.edu	37	2	48809015	48809015	+	Missense_Mutation	SNP	A	A	G			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr2:48809015A>G	ENST00000309835.3	+	1	1253	c.1243A>G	c.(1243-1245)Att>Gtt	p.I415V	STON1-GTF2A1L_ENST00000394754.1_Missense_Mutation_p.I415V|STON1-GTF2A1L_ENST00000405008.1_Missense_Mutation_p.I415V|STON1_ENST00000404752.1_Missense_Mutation_p.I415V|STON1-GTF2A1L_ENST00000402114.2_Missense_Mutation_p.I415V|STON1-GTF2A1L_ENST00000394751.3_Missense_Mutation_p.I415V|STON1-GTF2A1L_ENST00000309827.2_Missense_Mutation_p.I415V|STON1_ENST00000406226.1_Missense_Mutation_p.I415V					stonin 1											NS(1)|endometrium(1)|kidney(2)|large_intestine(9)|lung(19)|prostate(3)|skin(2)	37		all_hematologic(82;0.151)|Acute lymphoblastic leukemia(82;0.175)	Lung(47;0.101)|LUSC - Lung squamous cell carcinoma(58;0.151)			GGAGCAAGAAATTTCCTTGGA	0.393000													30	43					0	0	1	0	0
TNXB	7148	broad.mit.edu	37	6	32053641	32053641	+	Missense_Mutation	SNP	C	C	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr6:32053641C>T	ENST00000375244.3	-	7	3235	c.3034G>A	c.(3034-3036)Gtc>Atc	p.V1012I	TNXB_ENST00000375247.2_Missense_Mutation_p.V1012I			P22105	TENX_HUMAN	tenascin XB	1099	Fibronectin type-III 2.				actin cytoskeleton organization|cell adhesion|collagen metabolic process|elastic fiber assembly|signal transduction	extracellular space|intracellular|proteinaceous extracellular matrix	heparin binding|integrin binding			endometrium(1)|kidney(1)|large_intestine(1)|lung(4)|prostate(1)	8						GCCTGGCGGACGTCCCCTGGC	0.657000													25	41					0	0	1	0	0
NLRP6	171389	broad.mit.edu	37	11	284621	284621	+	Missense_Mutation	SNP	G	G	A			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr11:284621G>A	ENST00000534750.1	+	7	2721	c.2516G>A	c.(2515-2517)gGa>gAa	p.G839E	NLRP6_ENST00000312165.5_Missense_Mutation_p.G840E	NM_001276700.1	NP_001263629.1	P59044	NALP6_HUMAN	NLR family, pyrin domain containing 6	840						cytoplasm	ATP binding			breast(1)|skin(1)|upper_aerodigestive_tract(2)	4		all_cancers(49;1.12e-06)|all_epithelial(84;0.000375)|Breast(177;0.00122)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		all cancers(45;4.28e-28)|Epithelial(43;2.47e-27)|OV - Ovarian serous cystadenocarcinoma(40;4.66e-21)|BRCA - Breast invasive adenocarcinoma(625;3.57e-05)|Lung(200;0.0485)|LUSC - Lung squamous cell carcinoma(625;0.122)		CAGCACCAGGGATGCGGCCTG	0.692000													3	17					0	0	1	0	0
AGXT2	64902	broad.mit.edu	37	5	35039553	35039553	+	Missense_Mutation	SNP	C	C	T			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr5:35039553C>T	ENST00000231420.6	-	3	438	c.238G>A	c.(238-240)Gca>Aca	p.A80T		NM_031900.3	NP_114106.1	Q9BYV1	AGT2_HUMAN	alanine--glyoxylate aminotransferase 2	80					glyoxylate metabolic process|pyrimidine base metabolic process|pyrimidine nucleoside catabolic process	mitochondrial matrix	(R)-3-amino-2-methylpropionate-pyruvate transaminase activity|alanine-glyoxylate transaminase activity|pyridoxal phosphate binding			NS(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(18)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)	41	all_lung(31;4.52e-05)		COAD - Colon adenocarcinoma(61;0.174)|Colorectal(62;0.229)	GBM - Glioblastoma multiforme(108;0.181)	Glycine(DB00145)|L-Alanine(DB00160)|Pyridoxal Phosphate(DB00114)|Pyruvic acid(DB00119)	TGGAAATATGCCGTCACCACA	0.473000													4	74					0	0	1	0	0
AGRN	375790	broad.mit.edu	37	1	980571	980571	+	Frame_Shift_Del	DEL	C	C	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr1:980571delC	ENST00000379370.2	+	13	2335	c.2285delC	c.(2284-2286)gcfs	p.A762fs		NM_198576.3	NP_940978.2	O00468	AGRIN_HUMAN	agrin	762					axon guidance|clustering of voltage-gated sodium channels|muscarinic acetylcholine receptor signaling pathway|receptor clustering	basal lamina	laminin binding|structural constituent of cytoskeleton			breast(1)|central_nervous_system(2)|endometrium(8)|kidney(3)|large_intestine(2)|lung(20)|ovary(1)|prostate(1)|skin(3)|urinary_tract(1)	42	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;8.75e-19)|all_lung(118;2.3e-08)|Lung NSC(185;2.38e-06)|Renal(390;0.00183)|Breast(487;0.00354)|Hepatocellular(190;0.00826)|Myeloproliferative disorder(586;0.0122)|Ovarian(437;0.0308)|Lung SC(97;0.128)		UCEC - Uterine corpus endometrioid carcinoma (11;0.00462)|Epithelial(90;5.98e-38)|OV - Ovarian serous cystadenocarcinoma(86;5.43e-23)|Colorectal(212;5.97e-05)|COAD - Colon adenocarcinoma(227;0.000201)|Kidney(185;0.0024)|BRCA - Breast invasive adenocarcinoma(365;0.00246)|STAD - Stomach adenocarcinoma(132;0.00645)|KIRC - Kidney renal clear cell carcinoma(229;0.0354)|Lung(427;0.201)		CCGCCTGTGGCCCCCTTACAC	0.672													2	4	---	---	---	---					
SCN5A	6331	broad.mit.edu	37	3	38655531	38655531	+	Frame_Shift_Del	DEL	C	C	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr3:38655531delC	ENST00000413689.1	-	6	831	c.638delG	c.(637-639)gcfs	p.G213fs	SCN5A_ENST00000443581.1_Intron|SCN5A_ENST00000414099.2_Frame_Shift_Del_p.G213fs|SCN5A_ENST00000425664.1_Frame_Shift_Del_p.G213fs|SCN5A_ENST00000423572.2_Intron|SCN5A_ENST00000451551.2_Frame_Shift_Del_p.G213fs|SCN5A_ENST00000333535.4_Intron|SCN5A_ENST00000450102.2_Frame_Shift_Del_p.G213fs|SCN5A_ENST00000449557.2_Intron|SCN5A_ENST00000455624.2_Frame_Shift_Del_p.G213fs	NM_001099404.1|NM_001160160.1	NP_001092874.1|NP_001153632.1	Q14524	SCN5A_HUMAN	sodium channel, voltage-gated, type V, alpha subunit	213					blood circulation|cellular response to calcium ion|muscle contraction|regulation of heart contraction	sarcolemma|voltage-gated sodium channel complex	protein binding|voltage-gated sodium channel activity			NS(3)|breast(2)|central_nervous_system(3)|cervix(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(25)|lung(27)|ovary(6)|pancreas(3)|prostate(10)|skin(9)|upper_aerodigestive_tract(4)	107	Medulloblastoma(35;0.163)			KIRC - Kidney renal clear cell carcinoma(284;0.0822)|Kidney(284;0.1)	Benzonatate(DB00868)|Bepridil(DB01244)|Carbamazepine(DB00564)|Cocaine(DB00907)|Dibucaine(DB00527)|Disopyramide(DB00280)|Encainide(DB01228)|Ethotoin(DB00754)|Flecainide(DB01195)|Fosphenytoin(DB01320)|Hexylcaine(DB00473)|Indecainide(DB00192)|Lamotrigine(DB00555)|Lidocaine(DB00281)|Mephenytoin(DB00532)|Mexiletine(DB00379)|Mibefradil(DB01388)|Moricizine(DB00680)|Oxcarbazepine(DB00776)|Phenytoin(DB00252)|Prilocaine(DB00750)|Procainamide(DB01035)|Propafenone(DB01182)|Quinidine(DB00908)|Riluzole(DB00740)|Tocainide(DB01056)|Verapamil(DB00661)	CGACAAATTGCCTAGTTTTAT	0.463													2	4	---	---	---	---					
BDH1	622	broad.mit.edu	37	3	197273266	197273266	+	Frame_Shift_Del	DEL	T	T	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr3:197273266delT	ENST00000392379.1	-	3	450	c.49delA	c.(49-51)ccfs	p.T17fs	BDH1_ENST00000392378.2_Frame_Shift_Del_p.T17fs|BDH1_ENST00000441275.1_Intron|BDH1_ENST00000358186.2_Frame_Shift_Del_p.T17fs	NM_203314.2	NP_976059.1	Q02338	BDH_HUMAN	3-hydroxybutyrate dehydrogenase, type 1	17					cellular lipid metabolic process|ketone body biosynthetic process|ketone body catabolic process	mitochondrial matrix	3-hydroxybutyrate dehydrogenase activity			endometrium(2)|large_intestine(1)|lung(6)|ovary(1)|skin(1)	11	all_cancers(143;3.35e-10)|Ovarian(172;0.0418)|Breast(254;0.0437)	Lung NSC(153;0.118)	Epithelial(36;3.52e-24)|all cancers(36;1.79e-22)|OV - Ovarian serous cystadenocarcinoma(49;2.32e-19)|LUSC - Lung squamous cell carcinoma(58;1.02e-06)|Lung(62;1.34e-06)	GBM - Glioblastoma multiforme(93;0.0977)	NADH(DB00157)	GCACTTAGGGTTTTTCCTGGG	0.552													33	50	---	---	---	---					
EMG1	10436	broad.mit.edu	37	12	7084784	7084784	+	RNA	DEL	T	T	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr12:7084784delT	ENST00000546220.1	+	0	651				U47924.28_ENST00000261406.6_lincRNA|U47924.19_ENST00000564245.1_RNA			Q92979	NEP1_HUMAN	EMG1 N1-specific pseudouridine methyltransferase						ribosomal small subunit biogenesis	cytoplasm|nucleolus	rRNA (pseudouridine) methyltransferase activity|rRNA binding										TCAGCCATAGTTTTCCTGCCC	0.438													9	17	---	---	---	---					
UBE2Q2P2	100134869	broad.mit.edu	37	15	83040944	83040944	+	RNA	DEL	T	T	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr15:83040944delT	ENST00000558477.1	+	0	233					NR_004847.2																						AACAAAAATCTTTTTTTTTTT	0.313													2	4	---	---	---	---					
ZC3H7B	23264	broad.mit.edu	37	22	41721866	41721866	+	Frame_Shift_Del	DEL	C	C	-			TCGA-PR-A5PF-01A-11D-A35D-08	TCGA-PR-A5PF-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7c3bf12f-8590-4cdc-9a35-043406ed0ef7	92c39d4a-abec-4f9d-80d6-06eeb76b447e	g.chr22:41721866delC	ENST00000352645.4	+	4	486	c.229delC	c.(229-231)ccfs	p.P77fs	ZC3H7B_ENST00000351589.4_Frame_Shift_Del_p.P77fs	NM_017590.4	NP_060060.3	Q9UGR2	Z3H7B_HUMAN	zinc finger CCCH-type containing 7B	77					interspecies interaction between organisms	nucleus	nucleic acid binding|protein binding|zinc ion binding			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(4)|lung(11)|ovary(3)|prostate(3)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(3)	38						GGTGGCCCTGCCCCGGGAGCT	0.592													2	4	---	---	---	---