Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FAT2	2196	broad.mit.edu	37	5	150932752	150932752	+	Missense_Mutation	SNP	C	C	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:150932752C>G	ENST00000261800.5	-	5	4154	c.4142G>C	c.(4141-4143)tGg>tCg	p.W1381S		NM_001447.2	NP_001438.1	Q9NYQ8	FAT2_HUMAN	FAT atypical cadherin 2	1381	Cadherin 12.				epithelial cell migration|homophilic cell adhesion	cell-cell adherens junction|integral to membrane|nucleus	calcium ion binding			NS(6)|breast(3)|central_nervous_system(3)|cervix(5)|endometrium(15)|haematopoietic_and_lymphoid_tissue(4)|kidney(8)|large_intestine(61)|liver(1)|lung(60)|ovary(6)|prostate(5)|skin(5)|stomach(2)|upper_aerodigestive_tract(11)|urinary_tract(1)	196		Medulloblastoma(196;0.0912)|all_hematologic(541;0.104)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			GATGTTGAACCAGAAGAGTCC	0.552000													27	43					0	0	1	0	0
TELO2	9894	broad.mit.edu	37	16	1545588	1545588	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr16:1545588G>A	ENST00000262319.6	+	3	856	c.577G>A	c.(577-579)Gtc>Atc	p.V193I		NM_016111.3	NP_057195.2	Q9Y4R8	TELO2_HUMAN	telomere maintenance 2	193						chromosome, telomeric region|cytoplasm|membrane|nucleus	protein binding			NS(1)|endometrium(1)|kidney(5)|lung(9)|ovary(1)|skin(1)|urinary_tract(1)	19		Hepatocellular(780;0.219)				CGAGGAGGTCGTCCGGGTGCT	0.672000													31	48					0	0	1	0	0
KLRC1	3821	broad.mit.edu	37	12	10601988	10601988	+	Splice_Site	SNP	C	C	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr12:10601988C>A	ENST00000544822.1	-	6	725		c.e6-1		KLRC1_ENST00000347831.5_Splice_Site|KLRC1_ENST00000408006.3_Splice_Site|KLRC1_ENST00000536188.1_Splice_Site|KLRC1_ENST00000359151.3_Splice_Site	NM_213658.2	NP_998823.1	P26715	NKG2A_HUMAN	killer cell lectin-like receptor subfamily C, member 1						cell surface receptor linked signaling pathway|regulation of immune response	integral to plasma membrane	sugar binding|transmembrane receptor activity			NS(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(2)|lung(8)|skin(1)	16						CAATGACGTGCTAAATAAAGA	0.333000													4	237					0.00909568	0.00909568	1	1	0
TPSD1	23430	broad.mit.edu	37	16	1308192	1308192	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr16:1308192G>A	ENST00000211076.3	+	4	801	c.653G>A	c.(652-654)tGt>tAt	p.C218Y	TPSD1_ENST00000397534.2_Missense_Mutation_p.C211Y	NM_012217.2	NP_036349.1	Q9BZJ3	TRYD_HUMAN	tryptase delta 1	218	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(9)|skin(1)|stomach(2)|upper_aerodigestive_tract(3)	20		Hepatocellular(780;0.00369)				GACATGCTGTGTGCGGGGAGC	0.627000													10	28					0	0	1	0	0
AHNAK	79026	broad.mit.edu	37	11	62300247	62300247	+	Silent	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr11:62300247G>A	ENST00000378024.4	-	5	1916	c.1642C>T	c.(1642-1644)Cta>Tta	p.L548L	AHNAK_ENST00000530124.1_Intron|AHNAK_ENST00000257247.7_Intron	NM_001620.1	NP_001611.1	Q09666	AHNK_HUMAN	AHNAK nucleoprotein	548					nervous system development	nucleus	protein binding			NS(3)|autonomic_ganglia(1)|breast(10)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(2)|kidney(33)|large_intestine(40)|liver(1)|lung(108)|ovary(13)|pancreas(4)|prostate(5)|skin(16)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(6)	268		Melanoma(852;0.155)				GTTCCCTCTAGGTTTGGTGTC	0.507000													8	172					0	0	1	0	0
DNAH9	1770	broad.mit.edu	37	17	11584134	11584134	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr17:11584134G>A	ENST00000262442.3	+	19	3739	c.3671G>A	c.(3670-3672)cGc>cAc	p.R1224H	DNAH9_ENST00000454412.2_Missense_Mutation_p.R1224H	NM_001372.3	NP_001363.2	Q9NYC9	DYH9_HUMAN	dynein, axonemal, heavy chain 9	1224	Stem (By similarity).				cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4)	290		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		ACACTCCTCCGCCAGAGGTGC	0.532000													3	23					0	0	1	0	0
MAP4K3	8491	broad.mit.edu	37	2	39499514	39499514	+	Missense_Mutation	SNP	T	T	C			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:39499514T>C	ENST00000263881.3	-	26	2207	c.1883A>G	c.(1882-1884)aAt>aGt	p.N628S	MAP4K3_ENST00000341681.5_Missense_Mutation_p.N607S|MAP4K3_ENST00000536018.1_Missense_Mutation_p.N181S|MAP4K3_ENST00000437545.1_Missense_Mutation_p.N544S	NM_003618.3	NP_003609.2	Q8IVH8	M4K3_HUMAN	mitogen-activated protein kinase kinase kinase kinase 3	628	CNH.				JNK cascade		ATP binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			NS(1)|endometrium(4)|kidney(2)|large_intestine(8)|lung(17)|ovary(4)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	44		all_hematologic(82;0.211)				CCCTGGTAAATTATGGGAATA	0.328000													4	100					0	0	1	0	0
RAB3IL1	5866	broad.mit.edu	37	11	61675752	61675752	+	Missense_Mutation	SNP	G	G	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr11:61675752G>T	ENST00000394836.2	-	2	195	c.38C>A	c.(37-39)cCg>cAg	p.P13Q	RAB3IL1_ENST00000301773.5_Missense_Mutation_p.P60Q	NM_013401.2	NP_037533.2	Q8TBN0	R3GEF_HUMAN	RAB3A interacting protein (rabin3)-like 1	13							protein binding			central_nervous_system(1)|endometrium(2)|large_intestine(2)|liver(1)|lung(4)|skin(3)|urinary_tract(1)	14						AAGGGGCGGCGGGAGGCCCTG	0.677000													5	7					8.12818e-05	8.50624e-05	1	1	0
SAMD9L	219285	broad.mit.edu	37	7	92763468	92763468	+	Missense_Mutation	SNP	T	T	C			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr7:92763468T>C	ENST00000318238.4	-	5	3033	c.1817A>G	c.(1816-1818)aAc>aGc	p.N606S	SAMD9L_ENST00000437805.1_Missense_Mutation_p.N606S|SAMD9L_ENST00000411955.1_Missense_Mutation_p.N606S	NM_152703.2	NP_689916.2	Q8IVG5	SAM9L_HUMAN	sterile alpha motif domain containing 9-like	606										central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(23)|liver(2)|lung(31)|ovary(5)|prostate(2)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	88	all_cancers(62;4.15e-11)|all_epithelial(64;2.29e-10)|Breast(17;0.000675)|Lung NSC(181;0.0755)|all_lung(186;0.0989)		STAD - Stomach adenocarcinoma(171;0.000302)			AATACTGTGGTTTGTTAGTTC	0.368000													4	128					0	0	1	0	0
MYH2	4620	broad.mit.edu	37	17	10435136	10435136	+	Missense_Mutation	SNP	T	T	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr17:10435136T>A	ENST00000245503.5	-	22	2895	c.2511A>T	c.(2509-2511)aaA>aaT	p.K837N	MYH2_ENST00000397183.2_Missense_Mutation_p.K837N|CTC-297N7.7_ENST00000399342.2_RNA|CTC-297N7.7_ENST00000581304.1_RNA|MYH2_ENST00000532183.1_Intron|CTC-297N7.7_ENST00000587182.1_RNA	NM_017534.5	NP_060004.3	Q9UKX2	MYH2_HUMAN	myosin, heavy chain 2, skeletal muscle, adult	837					muscle filament sliding	muscle myosin complex|myosin filament|sarcomere	actin binding|ATP binding|calmodulin binding|microfilament motor activity|structural constituent of muscle			NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(16)|lung(99)|ovary(6)|pancreas(4)|prostate(3)|skin(8)|upper_aerodigestive_tract(2)|urinary_tract(4)	176						TGAAGAAGAGTTTCATCCAGG	0.403000													5	158					0	0	1	0	0
DNAH9	1770	broad.mit.edu	37	17	11684410	11684410	+	Missense_Mutation	SNP	A	A	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr17:11684410A>G	ENST00000262442.3	+	39	7705	c.7637A>G	c.(7636-7638)gAc>gGc	p.D2546G	DNAH9_ENST00000454412.2_Missense_Mutation_p.D2546G	NM_001372.3	NP_001363.2	Q9NYC9	DYH9_HUMAN	dynein, axonemal, heavy chain 9	2546	AAA 3 (By similarity).				cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4)	290		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		TTCATTGATGACATGAACATG	0.547000													4	40					0	0	1	0	0
NPIPA5	100288332	broad.mit.edu	37	16	15457701	15457701	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr16:15457701G>A	ENST00000360151.4	-	8	867	c.868C>T	c.(868-870)Ctc>Ttc	p.L290F		NM_001277325.1	NP_001264254.1			nuclear pore complex interacting protein family, member A5									p.L290F(2)									AGGGGAGTGAGCAGACACTCG	0.562000													4	133					0	0	1	0	0
TBC1D3P2	0	broad.mit.edu	37	17	60342504	60342504	+	RNA	SNP	T	T	C			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr17:60342504T>C	ENST00000581291.1	-	0	1649																				breast(2)|kidney(1)|lung(2)	5						CAGTGCTGGGTGCACTGCAGG	0.637000													4	60					0	0	1	0	0
TGFBI	7045	broad.mit.edu	37	5	135390519	135390519	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:135390519G>A	ENST00000442011.2	+	10	1540	c.1379G>A	c.(1378-1380)gGc>gAc	p.G460D	TGFBI_ENST00000305126.8_Missense_Mutation_p.G460D	NM_000358.2	NP_000349.1	Q15582	BGH3_HUMAN	transforming growth factor, beta-induced, 68kDa	460	FAS1 3.				angiogenesis|cell adhesion|cell proliferation|negative regulation of cell adhesion|response to stimulus|visual perception	extracellular space|proteinaceous extracellular matrix	integrin binding	p.G460D(1)		breast(6)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(2)|lung(8)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	32			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0233)			ACTCTGGGCGGCAAAAAACTG	0.423000													6	246					0	0	1	0	0
LCT	3938	broad.mit.edu	37	2	136594247	136594247	+	Silent	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:136594247G>A	ENST00000264162.2	-	1	503	c.493C>T	c.(493-495)Cta>Tta	p.L165L		NM_002299.2	NP_002290.2	P09848	LPH_HUMAN	lactase	165	4 X approximate repeats.				carbohydrate metabolic process|polysaccharide digestion	apical plasma membrane|integral to plasma membrane|membrane fraction	cation binding|glycosylceramidase activity|lactase activity			breast(6)|central_nervous_system(3)|cervix(1)|endometrium(8)|kidney(2)|large_intestine(26)|lung(57)|ovary(7)|pancreas(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(4)|urinary_tract(4)	124				BRCA - Breast invasive adenocarcinoma(221;0.169)		ATCCCAACTAGGTCCCCGAAG	0.577000													4	82					0	0	1	0	0
PLEKHG4	25894	broad.mit.edu	37	16	67316416	67316416	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr16:67316416G>A	ENST00000360461.5	+	9	3799	c.1264G>A	c.(1264-1266)Gac>Aac	p.D422N	PLEKHG4_ENST00000427155.2_Missense_Mutation_p.D422N|PLEKHG4_ENST00000379344.3_Missense_Mutation_p.D422N|PLEKHG4_ENST00000450733.1_Missense_Mutation_p.D341N	NM_001129727.1|NM_015432.3	NP_001123199.1|NP_056247.1	Q58EX7	PKHG4_HUMAN	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	422					regulation of Rho protein signal transduction	intracellular	Rho guanyl-nucleotide exchange factor activity			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(14)|ovary(2)|pancreas(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)	37				OV - Ovarian serous cystadenocarcinoma(108;0.00376)|Epithelial(162;0.0173)|all cancers(182;0.116)|Kidney(780;0.119)		GACGGCAATGGACAAGGCTGA	0.562000													7	54					0	0	1	0	0
RTF1	23168	broad.mit.edu	37	15	41769448	41769448	+	Missense_Mutation	SNP	T	T	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr15:41769448T>A	ENST00000389629.4	+	13	1658	c.1646T>A	c.(1645-1647)cTg>cAg	p.L549Q		NM_015138.4	NP_055953.3	Q92541	RTF1_HUMAN	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	549					histone modification|regulation of transcription, DNA-dependent|transcription initiation, DNA-dependent	nucleoplasm	protein binding|single-stranded DNA binding			central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(2)|lung(6)|ovary(2)|prostate(1)|skin(1)	18		all_cancers(109;1.79e-19)|all_epithelial(112;8.18e-17)|Lung NSC(122;3.16e-11)|all_lung(180;8.14e-10)|Melanoma(134;0.0179)|Colorectal(260;0.0946)|Ovarian(310;0.143)		OV - Ovarian serous cystadenocarcinoma(18;1.15e-16)|GBM - Glioblastoma multiforme(113;1.81e-06)|BRCA - Breast invasive adenocarcinoma(123;0.119)		GCAGAGGCCCTGGACCGCCAG	0.542000													14	125					0	0	1	0	0
NRAS	4893	broad.mit.edu	37	1	115256529	115256529	+	Missense_Mutation	SNP	T	T	C	rs11554290		TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr1:115256529T>C	ENST00000369535.4	-	3	435	c.182A>G	c.(181-183)cAa>cGa	p.Q61R		NM_002524.4	NP_002515.1	P01111	RASN_HUMAN	neuroblastoma RAS viral (v-ras) oncogene homolog	61			Q -> K (in neuroblastoma cell).|Q -> R (in lung carcinoma cell and melanoma; dbSNP:rs11554290).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	Golgi membrane|plasma membrane	GTP binding|GTPase activity	p.Q61R(817)|p.Q61L(175)|p.Q61P(23)|p.Q61K(1)		NS(134)|adrenal_gland(9)|autonomic_ganglia(9)|biliary_tract(6)|bone(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(11)|eye(3)|haematopoietic_and_lymphoid_tissue(1115)|kidney(3)|large_intestine(105)|liver(10)|lung(42)|meninges(2)|ovary(7)|pancreas(5)|prostate(8)|skin(1144)|soft_tissue(37)|stomach(5)|testis(8)|thyroid(359)|upper_aerodigestive_tract(28)|urinary_tract(13)	3085	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GTACTCTTCTTGTCCAGCTGT	0.458000	Q61L(C3A_LIVER)|Q61L(HEPG2_LIVER)|Q61L(HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(IPC298_SKIN)|Q61L(KMS21BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MELJUSO_SKIN)|Q61L(MHHES1_BONE)|Q61L(MOLP8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61P(TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(HT1197_URINARY_TRACT)|Q61R(KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(KU1919_URINARY_TRACT)|Q61R(NCIH2347_LUNG)|Q61R(ONS76_CENTRAL_NERVOUS_SYSTEM)|Q61R(SKMEL2_SKIN)|Q61R(SW1271_LUNG)|Q61R(TT2609C02_THYROID)	50	Mis		"""melanoma, MM, AML, thyroid"""				Noonan syndrome	TSP Lung(23;0.16)|Multiple Myeloma(1;<1E-6)			7	78					0	0	1	0	0
CRTC1	23373	broad.mit.edu	37	19	18888093	18888093	+	Silent	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr19:18888093C>T	ENST00000338797.6	+	15	1879	c.1854C>T	c.(1852-1854)atC>atT	p.I618I	CRTC1_ENST00000594658.1_Silent_p.I561I|CRTC1_ENST00000321949.8_Silent_p.I602I|CRTC1_ENST00000601916.1_Silent_p.I360I	NM_001098482.1	NP_001091952.1	Q6UUV9	CRTC1_HUMAN	CREB regulated transcription coactivator 1	602					interspecies interaction between organisms|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|nucleus|plasma membrane	cAMP response element binding protein binding|protein binding		CRTC1/MAML2(516)	NS(1)|breast(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(4)|lung(6)|ovary(1)|skin(1)	19						AACTCAAGATCGACCCCCTGA	0.642000													138	198					0	0	1	0	0
TMEM220	388335	broad.mit.edu	37	17	10628335	10628335	+	Missense_Mutation	SNP	C	C	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr17:10628335C>G	ENST00000341871.3	-	4	744	c.280G>C	c.(280-282)Gaa>Caa	p.E94Q	TMEM220_ENST00000580186.1_5'UTR|TMEM220_ENST00000455996.2_Missense_Mutation_p.E84Q|TMEM220_ENST00000578345.1_Missense_Mutation_p.E84Q	NM_001004313.1	NP_001004313.1	Q6QAJ8	TM220_HUMAN	transmembrane protein 220	94						integral to membrane				kidney(1)|large_intestine(1)|lung(1)|prostate(2)	5						CACCTGCCTTCTTCCTCATGT	0.473000													9	130					0	0	1	0	0
OR56A4	120793	broad.mit.edu	37	11	6024219	6024219	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr11:6024219C>T	ENST00000330728.4	-	1	205	c.160G>A	c.(160-162)Gca>Aca	p.A54T		NM_001005179.2	NP_001005179.2	Q8NGH8	O56A4_HUMAN	olfactory receptor, family 56, subfamily A, member 4	2					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|kidney(4)|large_intestine(5)|lung(17)|ovary(1)|skin(1)|urinary_tract(1)	32		Medulloblastoma(188;0.00776)|all_neural(188;0.0652)|Breast(177;0.114)		Epithelial(150;7.01e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		CTGGGAGATGCCATGTAAAGT	0.473000													20	35					0	0	1	0	0
KLHDC8B	200942	broad.mit.edu	37	3	49210376	49210376	+	Silent	SNP	A	A	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr3:49210376A>G	ENST00000332780.2	+	2	383	c.174A>G	c.(172-174)acA>acG	p.T58T	KLHDC8B_ENST00000476495.2_3'UTR	NM_173546.2	NP_775817.1	Q8IXV7	KLD8B_HUMAN	kelch domain containing 8B	58						cytoplasm				endometrium(1)|kidney(1)|large_intestine(2)|lung(1)|skin(1)|stomach(1)	7				BRCA - Breast invasive adenocarcinoma(193;8.01e-05)|Kidney(197;0.00217)|KIRC - Kidney renal clear cell carcinoma(197;0.00244)		CCTCGCACACATGGCTGGCAC	0.652000													5	51					0	0	1	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:209113112C>T	ENST00000415913.1	-	4	776	c.395G>A	c.(394-396)cGt>cAt	p.R132H	IDH1_ENST00000446179.1_Missense_Mutation_p.R132H|IDH1_ENST00000345146.2_Missense_Mutation_p.R132H			O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132			R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).|R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2774)|p.R132L(59)|p.R132V(1)|p.G131_R132>VL(1)		NS(1)|autonomic_ganglia(2)|biliary_tract(24)|bone(237)|central_nervous_system(3764)|endometrium(3)|haematopoietic_and_lymphoid_tissue(794)|kidney(2)|large_intestine(7)|lung(7)|prostate(6)|skin(5)|soft_tissue(12)|thyroid(22)|urinary_tract(1)	4887				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma								37	53					0	0	1	0	0
CAT	847	broad.mit.edu	37	11	34473715	34473715	+	Silent	SNP	A	A	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr11:34473715A>G	ENST00000241052.4	+	4	530	c.441A>G	c.(439-441)ggA>ggG	p.G147G		NM_001752.3	NP_001743.1	P04040	CATA_HUMAN	catalase	147					hydrogen peroxide catabolic process|negative regulation of apoptosis|positive regulation of cell division|protein tetramerization|purine base metabolic process|purine nucleotide catabolic process|UV protection	peroxisomal matrix|peroxisomal membrane	catalase activity|heme binding|NADP binding|protein homodimerization activity			breast(1)|cervix(2)|endometrium(3)|kidney(2)|large_intestine(6)|lung(5)|ovary(2)|pancreas(1)|stomach(1)|urinary_tract(3)	26		Lung NSC(402;2.76e-08)|Acute lymphoblastic leukemia(5;0.00143)|all_hematologic(20;0.0116)|Melanoma(852;0.027)		BRCA - Breast invasive adenocarcinoma(625;0.000995)	Fomepizole(DB01213)	ATCTCGTTGGAAATAACACCC	0.403000													26	58					0	0	1	0	0
SPATA31E1	286234	broad.mit.edu	37	9	90500387	90500387	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr9:90500387C>T	ENST00000325643.5	+	4	1051	c.985C>T	c.(985-987)Cgg>Tgg	p.R329W		NM_178828.4	NP_849150.3			SPATA31 subfamily E, member 1																		ATCCCAGCCACGGCATCTTCC	0.617000													15	11					0	0	1	0	0
SLC13A4	26266	broad.mit.edu	37	7	135378959	135378959	+	Missense_Mutation	SNP	C	C	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr7:135378959C>G	ENST00000354042.4	-	10	1733	c.1044G>C	c.(1042-1044)aaG>aaC	p.K348N		NM_012450.2	NP_036582.2	Q9UKG4	S13A4_HUMAN	solute carrier family 13 (sodium/sulfate symporter), member 4	348						integral to plasma membrane	sodium:sulfate symporter activity			breast(1)|central_nervous_system(2)|endometrium(3)|kidney(2)|large_intestine(6)|lung(7)|skin(1)|upper_aerodigestive_tract(2)	24						TCTTCTTCTTCTTGCTCAGAG	0.393000													6	126					0	0	1	0	0
ABCA7	10347	broad.mit.edu	37	19	1057960	1057960	+	Missense_Mutation	SNP	G	G	A	rs141237099	by1000genomes	TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr19:1057960G>A	ENST00000263094.6	+	36	5158	c.4927G>A	c.(4927-4929)Gtg>Atg	p.V1643M	ABCA7_ENST00000435683.2_Missense_Mutation_p.V1505M|ABCA7_ENST00000433129.1_Missense_Mutation_p.V1643M	NM_019112.3	NP_061985.2	Q8IZY2	ABCA7_HUMAN	ATP-binding cassette, sub-family A (ABC1), member 7	1643					phagocytosis|transmembrane transport	ATP-binding cassette (ABC) transporter complex|endosome membrane|Golgi membrane|integral to membrane|plasma membrane	ATP binding|ATPase activity|transporter activity			NS(1)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(7)|lung(22)|ovary(1)|pancreas(7)|prostate(4)|skin(3)|upper_aerodigestive_tract(1)	65		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CTTCTTCTCCGTGCCCAGCAC	0.522000													4	142					0	0	1	0	0
SCN3A	6328	broad.mit.edu	37	2	166010994	166010994	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:166010994C>T	ENST00000360093.3	-	11	1839	c.1348G>A	c.(1348-1350)Gaa>Aaa	p.E450K	SCN3A_ENST00000409101.3_Missense_Mutation_p.E450K|SCN3A_ENST00000283254.7_Missense_Mutation_p.E450K	NM_001081677.1	NP_001075146.1	Q9NY46	SCN3A_HUMAN	sodium channel, voltage-gated, type III, alpha subunit	450						voltage-gated sodium channel complex	voltage-gated sodium channel activity	p.E450K(1)		NS(1)|breast(7)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(19)|liver(2)|lung(47)|ovary(6)|prostate(3)|skin(10)|upper_aerodigestive_tract(4)|urinary_tract(3)	120					Lamotrigine(DB00555)	TTAAGCTGTTCGAGCATCTGC	0.403000													5	82					0	0	1	0	0
SPATA31D1	389763	broad.mit.edu	37	9	84608365	84608365	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr9:84608365G>A	ENST00000344803.2	+	4	3027	c.2980G>A	c.(2980-2982)Gtc>Atc	p.V994I		NM_001001670.2	NP_001001670.1			SPATA31 subfamily D, member 1																		CTCACCTGTCGTCCAAGAAGG	0.502000													73	99					0	0	1	0	0
NIPBL	25836	broad.mit.edu	37	5	36985023	36985023	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:36985023C>T	ENST00000282516.8	+	10	2240	c.1741C>T	c.(1741-1743)Ctt>Ttt	p.L581F	NIPBL_ENST00000504430.1_3'UTR|NIPBL_ENST00000448238.2_Missense_Mutation_p.L581F	NM_015384.4|NM_133433.3	NP_056199.2|NP_597677.2	Q6KC79	NIPBL_HUMAN	Nipped-B homolog (Drosophila)	581					brain development|cellular protein localization|cellular response to X-ray|cognition|developmental growth|ear morphogenesis|embryonic arm morphogenesis|embryonic digestive tract morphogenesis|external genitalia morphogenesis|eye morphogenesis|face morphogenesis|gall bladder development|maintenance of mitotic sister chromatid cohesion|metanephros development|negative regulation of transcription from RNA polymerase II promoter|outflow tract morphogenesis|positive regulation of histone deacetylation|regulation of developmental growth|regulation of embryonic development|regulation of hair cycle|response to DNA damage stimulus|sensory perception of sound|uterus morphogenesis	SMC loading complex	chromo shadow domain binding|histone deacetylase binding|protein C-terminus binding|protein N-terminus binding			autonomic_ganglia(1)|breast(4)|endometrium(9)|kidney(22)|large_intestine(21)|liver(1)|lung(47)|ovary(7)|pancreas(1)|prostate(1)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(4)	128	all_lung(31;0.000447)|Hepatocellular(1;0.108)		Epithelial(62;0.072)|COAD - Colon adenocarcinoma(61;0.14)|all cancers(62;0.191)|Colorectal(62;0.202)			TGTTTCTGTTCTTCAGGAAGA	0.388000													8	90					0	0	1	0	0
SLC26A4	5172	broad.mit.edu	37	7	107350576	107350576	+	Missense_Mutation	SNP	C	C	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr7:107350576C>A	ENST00000265715.3	+	19	2391	c.2167C>A	c.(2167-2169)Cat>Aat	p.H723N	SLC26A4_ENST00000544569.1_Missense_Mutation_p.H310N|SLC26A4_ENST00000541474.1_Missense_Mutation_p.H284N|SLC26A4_ENST00000543100.1_Missense_Mutation_p.H292N	NM_000441.1	NP_000432.1	O43511	S26A4_HUMAN	solute carrier family 26 (anion exchanger), member 4	723	STAS.		H -> R (in DFNB4 and PDS; common mutation in Korea and Japan).		regulation of pH|regulation of protein localization|sensory perception of sound	apical plasma membrane|integral to membrane	chloride transmembrane transporter activity|inorganic anion exchanger activity|iodide transmembrane transporter activity|secondary active sulfate transmembrane transporter activity			central_nervous_system(2)|endometrium(1)|kidney(5)|large_intestine(8)|lung(16)|ovary(3)|prostate(1)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(2)	46						TTTGACGGTCCATGATGCTAT	0.368000									Pendred syndrome				4	83					0.00909568	0.00909568	1	1	0
DENND3	22898	broad.mit.edu	37	8	142178542	142178542	+	Silent	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr8:142178542C>T	ENST00000519811.1	+	13	2263	c.2193C>T	c.(2191-2193)ggC>ggT	p.G731G	DENND3_ENST00000424248.1_Silent_p.G599G|DENND3_ENST00000262585.2_Silent_p.G651G			A2RUS2	DEND3_HUMAN	DENN/MADD domain containing 3	651										breast(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(19)|ovary(1)|prostate(3)|skin(4)|stomach(2)|urinary_tract(1)	55	all_cancers(97;7.36e-15)|all_epithelial(106;2.33e-13)|Lung NSC(106;1.23e-05)|all_lung(105;1.75e-05)|Ovarian(258;0.01)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.105)			TGCAGCTGGGCGACTTCATGA	0.587000													32	51					0	0	1	0	0
NIPBL	25836	broad.mit.edu	37	5	36972046	36972046	+	Splice_Site	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:36972046G>A	ENST00000282516.8	+	8	1270		c.e8-1		NIPBL_ENST00000504430.1_Splice_Site|NIPBL_ENST00000448238.2_Splice_Site	NM_015384.4|NM_133433.3	NP_056199.2|NP_597677.2	Q6KC79	NIPBL_HUMAN	Nipped-B homolog (Drosophila)						brain development|cellular protein localization|cellular response to X-ray|cognition|developmental growth|ear morphogenesis|embryonic arm morphogenesis|embryonic digestive tract morphogenesis|external genitalia morphogenesis|eye morphogenesis|face morphogenesis|gall bladder development|maintenance of mitotic sister chromatid cohesion|metanephros development|negative regulation of transcription from RNA polymerase II promoter|outflow tract morphogenesis|positive regulation of histone deacetylation|regulation of developmental growth|regulation of embryonic development|regulation of hair cycle|response to DNA damage stimulus|sensory perception of sound|uterus morphogenesis	SMC loading complex	chromo shadow domain binding|histone deacetylase binding|protein C-terminus binding|protein N-terminus binding			autonomic_ganglia(1)|breast(4)|endometrium(9)|kidney(22)|large_intestine(21)|liver(1)|lung(47)|ovary(7)|pancreas(1)|prostate(1)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(4)	128	all_lung(31;0.000447)|Hepatocellular(1;0.108)		Epithelial(62;0.072)|COAD - Colon adenocarcinoma(61;0.14)|all cancers(62;0.191)|Colorectal(62;0.202)			TCTATTTTTAGGATGGAGATT	0.378000													9	45					0	0	1	0	0
GINM1	116254	broad.mit.edu	37	6	149900982	149900982	+	Missense_Mutation	SNP	G	G	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr6:149900982G>T	ENST00000367419.5	+	5	563	c.442G>T	c.(442-444)Gat>Tat	p.D148Y		NM_138785.3	NP_620140.1			glycoprotein integral membrane 1																		TCAGCAAAAGGATGTCACTGA	0.333000													6	27					3.59834e-05	3.85536e-05	1	1	0
ZFHX3	463	broad.mit.edu	37	16	72821618	72821618	+	Silent	SNP	A	A	G	rs112443847		TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr16:72821618A>G	ENST00000268489.5	-	10	11229	c.10557T>C	c.(10555-10557)ggT>ggC	p.G3519G	ZFHX3_ENST00000397992.5_Silent_p.G2605G|AC004943.1_ENST00000584072.1_RNA	NM_006885.3	NP_008816.3	Q15911	ZFHX3_HUMAN	zinc finger homeobox 3	3519	Poly-Gly.				muscle organ development|negative regulation of myoblast differentiation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-dependent|positive regulation of myoblast differentiation	transcription factor complex	enzyme binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|transcription regulatory region DNA binding|zinc ion binding	p.G3519G(3)		NS(3)|breast(7)|cervix(2)|endometrium(18)|haematopoietic_and_lymphoid_tissue(5)|kidney(8)|large_intestine(22)|liver(1)|lung(46)|ovary(5)|pancreas(1)|prostate(15)|skin(6)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(11)	153		Ovarian(137;0.13)				cgccgccgccaccgccgccgc	0.716000													3	27					0	0	1	0	0
OBSCN	84033	broad.mit.edu	37	1	228481238	228481238	+	Silent	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr1:228481238C>T	ENST00000570156.2	+	46	12413	c.12339C>T	c.(12337-12339)cgC>cgT	p.R4113R	OBSCN_ENST00000284548.11_Silent_p.R3684R|OBSCN_ENST00000422127.1_Silent_p.R3684R|OBSCN_ENST00000366709.4_Silent_p.R803R|OBSCN_ENST00000366707.4_Silent_p.R803R|OBSCN_ENST00000359599.6_Silent_p.R2531R	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	3155	Ig-like 42.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				TGCAGATCCGCGGCCTCGTGG	0.637000													26	78					0	0	1	0	0
GPR133	283383	broad.mit.edu	37	12	131476803	131476803	+	Missense_Mutation	SNP	C	C	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr12:131476803C>A	ENST00000261654.5	+	8	1391	c.832C>A	c.(832-834)Ccc>Acc	p.P278T	RP11-76C10.5_ENST00000542980.1_lincRNA|GPR133_ENST00000535015.1_Missense_Mutation_p.P310T	NM_198827.3	NP_942122.2	Q6QNK2	GP133_HUMAN	G protein-coupled receptor 133	278					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(2)|breast(2)|endometrium(6)|kidney(1)|large_intestine(12)|lung(20)|ovary(3)|pancreas(6)|prostate(6)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(4)	67	all_neural(191;0.0982)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.68e-06)|all cancers(50;2.71e-06)|Epithelial(86;6.75e-06)		TGCCTACCATCCCATCATAAC	0.403000													15	237					4.14922e-12	4.55402e-12	1	1	0
OR2W3	343171	broad.mit.edu	37	1	248059036	248059036	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr1:248059036C>T	ENST00000537741.1	+	3	405	c.148C>T	c.(148-150)Cgg>Tgg	p.R50W	OR2W3_ENST00000360358.3_Missense_Mutation_p.R50W			Q7Z3T1	OR2W3_HUMAN	olfactory receptor, family 2, subfamily W, member 3	50					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|kidney(2)|large_intestine(2)|lung(33)|ovary(1)|pancreas(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(3)	49	all_cancers(71;0.000139)|all_epithelial(71;1.58e-05)|Breast(184;0.0117)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0319)			CCTGGTGTCCCGGCTGGACCC	0.587000													18	128					0	0	1	0	0
LAMA4	3910	broad.mit.edu	37	6	112496653	112496653	+	Missense_Mutation	SNP	C	C	T			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr6:112496653C>T	ENST00000230538.7	-	11	1616	c.1219G>A	c.(1219-1221)Gaa>Aaa	p.E407K	LAMA4_ENST00000389463.4_Missense_Mutation_p.E400K|LAMA4_ENST00000424408.2_Missense_Mutation_p.E400K|LAMA4_ENST00000522006.1_Missense_Mutation_p.E400K	NM_001105206.2	NP_001098676.2	Q16363	LAMA4_HUMAN	laminin, alpha 4	407	Domain II and I.				cell adhesion|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	laminin-1 complex	extracellular matrix structural constituent|receptor binding			NS(1)|breast(6)|central_nervous_system(2)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(18)|lung(42)|ovary(4)|pancreas(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(8)	100		all_cancers(87;0.000196)|all_hematologic(75;0.000114)|all_epithelial(87;0.00542)|Colorectal(196;0.0209)		all cancers(137;0.0335)|OV - Ovarian serous cystadenocarcinoma(136;0.0578)|Epithelial(106;0.0748)|BRCA - Breast invasive adenocarcinoma(108;0.242)		TCATGCTCTTCCCCATAATAG	0.468000													77	102					0	0	1	0	0
SNX6	58533	broad.mit.edu	37	14	35074873	35074873	+	Silent	SNP	T	T	C			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr14:35074873T>C	ENST00000362031.4	-	5	387	c.357A>G	c.(355-357)ctA>ctG	p.L119L	SNX6_ENST00000396534.3_5'UTR|SNX6_ENST00000396526.3_5'UTR|SNX6_ENST00000355110.5_5'UTR	NM_152233.2	NP_689419.2	Q9UNH7	SNX6_HUMAN	sorting nexin 6	107	PX.				cell communication|intracellular protein transport|negative regulation of epidermal growth factor receptor activity|negative regulation of transcription, DNA-dependent|negative regulation of transforming growth factor beta receptor signaling pathway|retrograde transport, endosome to Golgi	cytoplasmic vesicle membrane|early endosome membrane|nucleus	phosphatidylinositol binding|protein homodimerization activity			endometrium(4)|lung(1)|ovary(1)	6	Breast(36;0.0473)|Hepatocellular(127;0.158)		LUAD - Lung adenocarcinoma(48;0.00169)|Lung(238;0.00199)|Epithelial(34;0.187)	GBM - Glioblastoma multiforme(112;0.0245)		CAAGCTTCTGTAGTTTTTCCC	0.363000													6	56					0	0	1	0	0
ALDH1L1	10840	broad.mit.edu	37	3	125831672	125831672	+	Nonsense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr3:125831672G>A	ENST00000393434.2	-	19	2483	c.2134C>T	c.(2134-2136)Cga>Tga	p.R712*	ALDH1L1_ENST00000452905.2_Nonsense_Mutation_p.R611*|ALDH1L1_ENST00000273450.3_Nonsense_Mutation_p.R722*|ALDH1L1_ENST00000393431.2_3'UTR|ALDH1L1_ENST00000472186.1_Nonsense_Mutation_p.R712*	NM_012190.3	NP_036322.2	O75891	AL1L1_HUMAN	aldehyde dehydrogenase 1 family, member L1	712	Aldehyde dehydrogenase.				10-formyltetrahydrofolate catabolic process|biosynthetic process		acyl carrier activity|cofactor binding|formyltetrahydrofolate dehydrogenase activity|hydroxymethyl-, formyl- and related transferase activity|methyltransferase activity			NS(1)|breast(2)|central_nervous_system(3)|endometrium(2)|kidney(5)|large_intestine(10)|lung(22)|ovary(3)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	52				GBM - Glioblastoma multiforme(114;0.0462)	Tetrahydrofolic acid(DB00116)	ACAAAGAGTCGGCCTGCTGCA	0.557000													9	78					0	0	1	0	0
ZDBF2	57683	broad.mit.edu	37	2	207171695	207171695	+	Missense_Mutation	SNP	G	G	A			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:207171695G>A	ENST00000374423.3	+	5	2829	c.2443G>A	c.(2443-2445)Gtt>Att	p.V815I		NM_020923.1	NP_065974.1	Q9HCK1	ZDBF2_HUMAN	zinc finger, DBF-type containing 2	815							nucleic acid binding|zinc ion binding			endometrium(4)|kidney(5)|large_intestine(28)|lung(50)|ovary(4)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	95						GGAAGAAACTGTTGATCTGGA	0.348000													5	55					0	0	1	0	0
UTP15	84135	broad.mit.edu	37	5	72866466	72866466	+	Silent	SNP	C	C	G			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:72866466C>G	ENST00000296792.4	+	6	858	c.603C>G	c.(601-603)ctC>ctG	p.L201L	UTP15_ENST00000543251.1_Silent_p.L11L|UTP15_ENST00000508491.1_Silent_p.L182L	NM_032175.2	NP_115551.2	Q8TED0	UTP15_HUMAN	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	201					rRNA processing	cytoplasm|nucleolus				endometrium(1)|kidney(1)|large_intestine(3)|lung(7)|ovary(1)|skin(2)	15		Lung NSC(167;0.00405)|Ovarian(174;0.0129)		OV - Ovarian serous cystadenocarcinoma(47;7.76e-55)		AGAGTGTTCTCTCCGTTGAGC	0.398000													11	102					0	0	1	0	0
DBI	1622	broad.mit.edu	37	2	120128319	120128319	+	Frame_Shift_Del	DEL	G	G	-			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr2:120128319delG	ENST00000542275.1	+	3	398	c.314delG	c.(313-315)cgfs	p.R105fs	DBI_ENST00000535617.1_Frame_Shift_Del_p.R86fs|DBI_ENST00000535757.1_Frame_Shift_Del_p.R61fs|DBI_ENST00000460901.1_3'UTR|DBI_ENST00000393103.2_Frame_Shift_Del_p.R45fs|DBI_ENST00000409094.1_Frame_Shift_Del_p.R61fs|DBI_ENST00000355857.3_Frame_Shift_Del_p.R44fs|DBI_ENST00000311521.4_Frame_Shift_Del_p.R61fs	NM_001178017.1	NP_001171488.1	P07108	ACBP_HUMAN	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	44					transport		benzodiazepine receptor binding|fatty-acyl-CoA binding			kidney(1)|lung(4)|skin(1)	6						GTTTAAGAACGGCCCGGGATG	0.428													13	31	---	---	---	---					
CC2D2A	57545	broad.mit.edu	37	4	15513005	15513007	+	In_Frame_Del	DEL	GAA	GAA	-	rs112367037		TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr4:15513005_15513007delGAA	ENST00000424120.1	+	8	930_932	c.676_678delGAA	c.(676-678)del	p.E229del	CC2D2A_ENST00000413206.1_In_Frame_Del_p.E229del|CC2D2A_ENST00000389652.5_In_Frame_Del_p.E180del|CC2D2A_ENST00000513811.1_3'UTR|CC2D2A_ENST00000503292.1_In_Frame_Del_p.E229del			Q9P2K1	C2D2A_HUMAN	coiled-coil and C2 domain containing 2A	229	Poly-Glu.				cell projection organization	cilium|microtubule basal body				NS(1)|breast(2)|central_nervous_system(1)|endometrium(6)|kidney(1)|large_intestine(8)|lung(5)|ovary(1)|pancreas(2)|prostate(2)|skin(1)|urinary_tract(2)	32						GGAGGAAGGGGAAGAAGAAGAAC	0.443													8	13	---	---	---	---					
CPEB4	80315	broad.mit.edu	37	5	173380262	173380265	+	Frame_Shift_Del	DEL	AGAT	AGAT	-			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr5:173380262_173380265delAGAT	ENST00000265085.5	+	9	3403_3406	c.1949_1952delAGAT	c.(1948-1953)gafs	p.EI650fs	CPEB4_ENST00000520867.1_Frame_Shift_Del_p.EI625fs|CPEB4_ENST00000522336.1_Frame_Shift_Del_p.EI260fs|CPEB4_ENST00000334035.5_Frame_Shift_Del_p.EI633fs|CPEB4_ENST00000519467.1_3'UTR|CPEB4_ENST00000517880.1_Frame_Shift_Del_p.EI243fs|CPEB4_ENST00000519835.1_Frame_Shift_Del_p.EI625fs	NM_030627.2	NP_085130.2	Q17RY0	CPEB4_HUMAN	cytoplasmic polyadenylation element binding protein 4	650	RRM 2.						nucleotide binding|RNA binding			NS(1)|endometrium(4)|kidney(2)|large_intestine(4)|lung(5)|prostate(1)|stomach(1)|upper_aerodigestive_tract(2)	20	Renal(175;0.000159)|Lung NSC(126;0.0128)|all_lung(126;0.0202)	Medulloblastoma(196;0.0399)|all_neural(177;0.0966)	Kidney(164;3.85e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000183)			CAGCATGGAGAGATAGATAAACGG	0.402													20	83	---	---	---	---					
SLC39A7	7922	broad.mit.edu	37	6	33169301	33169301	+	Frame_Shift_Del	DEL	C	C	-			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr6:33169301delC	ENST00000374677.3	+	1	652	c.279delC	c.(277-279)agfs	p.S93fs	SLC39A7_ENST00000374675.3_Frame_Shift_Del_p.S93fs	NM_006979.2	NP_008910.2	Q92504	S39A7_HUMAN	solute carrier family 39 (zinc transporter), member 7	93	His-rich.					endoplasmic reticulum membrane|integral to membrane|membrane fraction	protein binding|zinc ion transmembrane transporter activity			NS(1)|breast(3)|endometrium(2)|large_intestine(5)|lung(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	18						ATGGCCATAGCCATGGCTACT	0.552													35	44	---	---	---	---					
ROBO3	64221	broad.mit.edu	37	11	124750448	124750453	+	In_Frame_Del	DEL	CGGAGT	CGGAGT	-	rs55725290		TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr11:124750448_124750453delCGGAGT	ENST00000397801.1	+	27	4285_4290	c.4093_4098delCGGAGT	c.(4093-4098)del	p.RS1367del	ROBO3_ENST00000543966.1_In_Frame_Del_p.RS130del|ROBO3_ENST00000538940.1_In_Frame_Del_p.RS1345del|ROBO3_ENST00000525482.1_3'UTR	NM_022370.3	NP_071765.2	Q96MS0	ROBO3_HUMAN	roundabout, axon guidance receptor, homolog 3 (Drosophila)	1367					axon midline choice point recognition	integral to membrane	receptor activity			breast(2)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(17)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)	35	all_hematologic(175;0.215)	Lung NSC(97;0.0177)|all_lung(97;0.0179)|Medulloblastoma(222;0.0425)|Breast(109;0.0481)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;1.5e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0296)		TGgccggagccggagtcggagtcaga	0.660													6	3	---	---	---	---					
RP13-329D4.3	0	broad.mit.edu	37	20	26113543	26113543	+	RNA	DEL	A	A	-			TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr20:26113543delA	ENST00000416563.1	-	0	250																											TCTTTGCCTTAACAACATTAT	0.363													3	4	---	---	---	---					
RP5-1043L13.1	0	broad.mit.edu	37	20	58883399	58883400	+	RNA	INS	-	-	T	rs149794923	by1000genomes	TCGA-W9-A837-01A-11D-A36O-08	TCGA-W9-A837-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4cde89bf-7a49-4ec1-8cbb-505e17a13016	4c85a4ba-ea92-4b99-9c08-0b4943620dc9	g.chr20:58883399_58883400insT	ENST00000432910.1	+	0	332					NR_046099.1																						ggaccgggaaacagatgcttac	0.569													3	6	---	---	---	---