Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RTEL1	51750	broad.mit.edu	37	20	62324513	62324513	+	Missense_Mutation	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr20:62324513C>T	ENST00000318100.4	+	30	3696	c.2869C>T	c.(2869-2871)Cgg>Tgg	p.R957W	RTEL1_ENST00000370003.1_Missense_Mutation_p.R202W|RTEL1_ENST00000370018.3_Missense_Mutation_p.R957W|RTEL1-TNFRSF6B_ENST00000482936.1_Missense_Mutation_p.R957W|RTEL1_ENST00000360203.5_Missense_Mutation_p.R957W|RTEL1_ENST00000508582.2_Missense_Mutation_p.R981W			Q9NZ71	RTEL1_HUMAN	regulator of telomere elongation helicase 1	957					DNA repair|regulation of double-strand break repair via homologous recombination|telomere maintenance	nucleus	ATP binding|ATP-dependent DNA helicase activity|DNA binding|iron-sulfur cluster binding|metal ion binding			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(3)|lung(12)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	24	all_cancers(38;6.47e-12)|all_epithelial(29;3.75e-13)		Epithelial(9;1.25e-09)|all cancers(9;5.13e-09)|BRCA - Breast invasive adenocarcinoma(10;7.26e-05)|OV - Ovarian serous cystadenocarcinoma(5;0.00223)|Colorectal(105;0.107)			CCAGTTTGTGCGGCCCCACCA	0.597000													4	246					0	0	1	0	0
MORC2	22880	broad.mit.edu	37	22	31328609	31328609	+	Silent	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr22:31328609T>C	ENST00000215862.4	-	24	3847	c.2484A>G	c.(2482-2484)gaA>gaG	p.E828E	MORC2_ENST00000397641.2_Silent_p.E890E	NM_014941.1	NP_055756.1	Q9Y6X9	MORC2_HUMAN	MORC family CW-type zinc finger 2	890							ATP binding|zinc ion binding			breast(2)|kidney(2)|large_intestine(5)|lung(4)|ovary(2)|pancreas(1)|skin(4)|upper_aerodigestive_tract(1)	21						TGCGGAGGCATTCGGAAGTGG	0.597000													19	66					0	0	1	0	0
SLC25A48	153328	broad.mit.edu	37	5	135188391	135188391	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr5:135188391G>A	ENST00000274513.5	+	4	474	c.302G>A	c.(301-303)cGc>cAc	p.R101H	SLC25A48_ENST00000425402.1_Intron|SLC25A48_ENST00000433282.2_Missense_Mutation_p.R47H|SLC25A48_ENST00000420621.1_Missense_Mutation_p.R101H|SLC25A48_ENST00000412661.2_Missense_Mutation_p.R101H			Q6ZT89	S2548_HUMAN	solute carrier family 25, member 48	101					transmembrane transport	integral to membrane|mitochondrial inner membrane	binding			NS(1)|breast(1)|central_nervous_system(1)|kidney(1)|large_intestine(2)|lung(3)|skin(1)	10						AGTCCTCCCCGCACGCTGTCA	0.647000													4	184					0	0	1	0	0
ACACA	31	broad.mit.edu	37	17	35549066	35549066	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr17:35549066G>A	ENST00000353139.5	-	37	4862	c.4381C>T	c.(4381-4383)Cgt>Tgt	p.R1461C	ACACA_ENST00000394406.2_Missense_Mutation_p.R1424C|ACACA_ENST00000360679.3_Missense_Mutation_p.R1366C|ACACA_ENST00000335166.5_Missense_Mutation_p.R1346C	NM_198834.1|NM_198839.1	NP_942131.1|NP_942136.1	Q13085	ACACA_HUMAN	acetyl-CoA carboxylase alpha	1424					acetyl-CoA metabolic process|energy reserve metabolic process|fatty acid biosynthetic process|long-chain fatty-acyl-CoA biosynthetic process|positive regulation of cellular metabolic process|protein homotetramerization|triglyceride biosynthetic process	cytosol	acetyl-CoA carboxylase activity|ATP binding|biotin carboxylase activity|metal ion binding|protein binding	p.R1461C(1)|p.R1366C(1)		NS(2)|breast(5)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(24)|lung(23)|ovary(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	83		Breast(25;0.00157)|Ovarian(249;0.15)			Biotin(DB00121)	ATGATTGCACGAACAAAGAAC	0.478000													43	40					0	0	1	0	0
NUP205	23165	broad.mit.edu	37	7	135272653	135272653	+	Silent	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr7:135272653A>G	ENST00000285968.6	+	10	1412	c.1386A>G	c.(1384-1386)gaA>gaG	p.E462E	NUP205_ENST00000440390.2_Intron	NM_015135.2	NP_055950.1	Q92621	NU205_HUMAN	nucleoporin 205kDa	462					carbohydrate metabolic process|glucose transport|mRNA transport|protein import into nucleus, docking|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear pore	protein binding			breast(4)|central_nervous_system(2)|endometrium(9)|kidney(7)|large_intestine(17)|liver(4)|lung(36)|ovary(5)|prostate(1)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	93						TTGCTCTAGAATATTGGTGTC	0.468000													4	74					0	0	1	0	0
MYOC	4653	broad.mit.edu	37	1	171605167	171605167	+	Nonsense_Mutation	SNP	A	A	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr1:171605167A>T	ENST00000037502.5	-	3	1472	c.1413T>A	c.(1411-1413)taT>taA	p.Y471*		NM_000261.1	NP_000252.1	Q99972	MYOC_HUMAN	myocilin, trabecular meshwork inducible glucocorticoid response	471	Olfactomedin-like.		Y -> C (in GLC1A; uncertain pathogenicity).		anatomical structure morphogenesis	cilium|extracellular space|rough endoplasmic reticulum	structural molecule activity			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(4)|lung(12)|ovary(2)|prostate(1)|urinary_tract(2)	28	all_cancers(6;5.47e-10)|all_hematologic(923;0.088)|Acute lymphoblastic leukemia(37;0.181)					TGCTGTACTTATAGCGGTTCT	0.488000													25	110					0	0	1	0	0
SLC6A10P	0	broad.mit.edu	37	16	32890950	32890950	+	RNA	SNP	A	A	G	rs151263854	by1000genomes	TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr16:32890950A>G	ENST00000330048.5	-	0	3016					NR_003083.2																						ATACACCCAGACCACCACCAC	0.637000													3	44					0	0	1	0	0
FGD1	2245	broad.mit.edu	37	X	54497147	54497147	+	Silent	SNP	T	T	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chrX:54497147T>G	ENST00000375135.3	-	3	1261	c.528A>C	c.(526-528)ccA>ccC	p.P176P		NM_004463.2	NP_004454.2	P98174	FGD1_HUMAN	FYVE, RhoGEF and PH domain containing 1	176	Pro-rich.				actin cytoskeleton organization|apoptosis|filopodium assembly|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|organ morphogenesis|regulation of Cdc42 GTPase activity|regulation of cell shape|small GTPase mediated signal transduction	cytoskeleton|cytosol|Golgi apparatus|lamellipodium|nucleus|plasma membrane|ruffle	metal ion binding|Rho guanyl-nucleotide exchange factor activity|small GTPase binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(10)|lung(8)|ovary(3)|pancreas(1)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	39						TGGGCTCCAGTGGGGGGGGCA	0.662000													4	13					0	0	1	0	0
U2SURP	23350	broad.mit.edu	37	3	142720480	142720480	+	Missense_Mutation	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr3:142720480A>G	ENST00000473835.2	+	1	100	c.10A>G	c.(10-12)Aaa>Gaa	p.K4E	U2SURP_ENST00000397933.2_5'UTR|U2SURP_ENST00000493598.2_Missense_Mutation_p.K4E	NM_001080415.1	NP_001073884.1	O15042	SR140_HUMAN	U2 snRNP-associated SURP domain containing	4					RNA processing	nucleus	nucleotide binding|RNA binding			NS(1)|breast(2)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(12)|ovary(2)|pancreas(1)|prostate(1)|skin(1)	31						GATGGCGGACAAAACGCCAGG	0.587000													21	30					0	0	1	0	0
KRT25	147183	broad.mit.edu	37	17	38906790	38906790	+	Silent	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr17:38906790C>T	ENST00000312150.4	-	6	1077	c.1017G>A	c.(1015-1017)gcG>gcA	p.A339A		NM_181534.3	NP_853512.1	Q7Z3Z0	K1C25_HUMAN	keratin 25	339	Coil 2.|Rod.					cytoplasm|intermediate filament	structural molecule activity	p.A339A(2)		endometrium(1)|large_intestine(4)|lung(5)|ovary(2)|prostate(4)	16		Breast(137;0.00526)				CCTGGATCTGCGCCAGCTGCG	0.562000													23	247					0	0	1	0	0
EBF3	253738	broad.mit.edu	37	10	131639180	131639180	+	Missense_Mutation	SNP	C	C	T	rs138447716		TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr10:131639180C>T	ENST00000368648.3	-	14	1534	c.1462G>A	c.(1462-1464)Gcc>Acc	p.A488T	EBF3_ENST00000355311.5_Missense_Mutation_p.A497T	NM_001005463.2	NP_001005463.1	Q9H4W6	COE3_HUMAN	early B-cell factor 3	497	Pro/Ser/Thr-rich.				multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|metal ion binding|protein binding			central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(8)|lung(23)|ovary(1)|pancreas(1)|prostate(1)|skin(1)	44		all_cancers(35;1.8e-08)|all_epithelial(44;8.26e-08)|Lung NSC(174;0.0091)|all_lung(145;0.0123)|Breast(234;0.039)|all_neural(114;0.0722)|Colorectal(57;0.0764)		OV - Ovarian serous cystadenocarcinoma(35;0.00513)		CTGGCCATGGCGCCACTTCCA	0.547000													12	177					0	0	1	0	0
CLIP1	6249	broad.mit.edu	37	12	122845629	122845629	+	Translation_Start_Site	SNP	G	G	A	rs111985493		TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr12:122845629G>A	ENST00000545889.1	-	0	134				CLIP1_ENST00000358808.2_Silent_p.N294N|CLIP1_ENST00000361654.4_Silent_p.N294N|CLIP1_ENST00000540338.1_Silent_p.N294N|CLIP1_ENST00000537178.1_Silent_p.N294N|CLIP1_ENST00000302528.7_Silent_p.N294N			P30622	CLIP1_HUMAN	CAP-GLY domain containing linker protein 1						mitotic prometaphase|positive regulation of microtubule polymerization	centrosome|cytosol|endosome|intermediate filament|kinetochore	nucleic acid binding|protein homodimerization activity|zinc ion binding			NS(1)|breast(5)|endometrium(4)|kidney(5)|large_intestine(16)|liver(1)|lung(21)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	60	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.81e-05)|Epithelial(86;6.85e-05)|BRCA - Breast invasive adenocarcinoma(302;0.226)		GCCTCACTGCGTTGGCCTTGG	0.562000													14	91					0	0	1	0	0
OR4A16	81327	broad.mit.edu	37	11	55111417	55111417	+	Silent	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr11:55111417C>T	ENST00000314721.2	+	1	791	c.741C>T	c.(739-741)ctC>ctT	p.L247L		NM_001005274.1	NP_001005274.1	Q8NH70	O4A16_HUMAN	olfactory receptor, family 4, subfamily A, member 16	247					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(28)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)	51						TGGTTGCCCTCGTTTTTGTTC	0.398000													30	48					0	0	1	0	0
DUOX1	53905	broad.mit.edu	37	15	45442843	45442843	+	Silent	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr15:45442843T>C	ENST00000321429.4	+	23	3239	c.2832T>C	c.(2830-2832)ccT>ccC	p.P944P	DUOX1_ENST00000389037.3_Silent_p.P944P|DUOX1_ENST00000561166.1_Silent_p.P590P	NM_017434.3	NP_059130.2	Q9NRD9	DUOX1_HUMAN	dual oxidase 1	944					cuticle development|cytokine-mediated signaling pathway|hormone biosynthetic process|hydrogen peroxide biosynthetic process|hydrogen peroxide catabolic process|response to cAMP|superoxide anion generation	apical plasma membrane|integral to membrane	calcium ion binding|electron carrier activity|flavin adenine dinucleotide binding|heme binding|NAD(P)H oxidase activity|NADP binding|peroxidase activity			breast(2)|central_nervous_system(1)|endometrium(5)|kidney(5)|large_intestine(13)|lung(16)|ovary(6)|prostate(1)|skin(3)|stomach(4)|upper_aerodigestive_tract(1)	57		all_cancers(109;5.7e-11)|all_epithelial(112;4.65e-09)|Lung NSC(122;3.55e-06)|all_lung(180;2.56e-05)|Melanoma(134;0.027)		all cancers(107;5.77e-18)|GBM - Glioblastoma multiforme(94;5.11e-07)|COAD - Colon adenocarcinoma(120;0.071)|Colorectal(133;0.0717)		TGGAGGTGCCTGAAGTCATCA	0.602000													5	68					0	0	1	0	0
POF1B	79983	broad.mit.edu	37	X	84614572	84614572	+	Missense_Mutation	SNP	C	C	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chrX:84614572C>A	ENST00000262753.4	-	4	566	c.421G>T	c.(421-423)Gta>Tta	p.V141L	POF1B_ENST00000373145.3_Missense_Mutation_p.V141L	NM_024921.3	NP_079197.3	Q8WVV4	POF1B_HUMAN	premature ovarian failure, 1B	141							actin binding			central_nervous_system(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(3)|liver(2)|lung(17)|ovary(1)|prostate(1)	35						GGATTTTGTACTACATATTTC	0.328000													37	53					3.03874e-20	3.03874e-20	1	1	0
OR11H4	390442	broad.mit.edu	37	14	20711005	20711005	+	Missense_Mutation	SNP	G	G	A	rs142720326	byFrequency	TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr14:20711005G>A	ENST00000315409.2	+	1	108	c.55G>A	c.(55-57)Gtg>Atg	p.V19M		NM_001004479.1	NP_001004479.1	Q8NGC9	O11H4_HUMAN	olfactory receptor, family 11, subfamily H, member 4	19					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(11)|large_intestine(3)|lung(11)|ovary(1)|upper_aerodigestive_tract(1)	29	all_cancers(95;0.000888)		Epithelial(56;1.75e-06)|all cancers(55;1.22e-05)	GBM - Glioblastoma multiforme(265;0.0146)		AACACACATCGTGACAGAGTT	0.418000													6	64					0	0	1	0	0
HSF4	3299	broad.mit.edu	37	16	67203680	67203680	+	Missense_Mutation	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr16:67203680T>C	ENST00000264009.8	+	15	2436	c.1471T>C	c.(1471-1473)Tcc>Ccc	p.S491P	HSF4_ENST00000584272.1_Missense_Mutation_p.S461P|HSF4_ENST00000521374.1_Missense_Mutation_p.S491P|HSF4_ENST00000421453.1_Missense_Mutation_p.S461P	NM_001040667.2	NP_001035757.1	Q9ULV5	HSF4_HUMAN	heat shock transcription factor 4	491					response to stress	nucleus	sequence-specific DNA binding transcription factor activity|transcription corepressor activity			central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(3)|prostate(1)|skin(1)	12		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0143)|Epithelial(162;0.0335)|all cancers(182;0.184)		AGCCAGTCCCTCCCCCTAAGA	0.662000											OREG0023873	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	4	142					0	0	1	0	0
TRRAP	8295	broad.mit.edu	37	7	98547852	98547852	+	Silent	SNP	C	C	T	rs113411331		TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr7:98547852C>T	ENST00000359863.4	+	37	5489	c.5280C>T	c.(5278-5280)aaC>aaT	p.N1760N	TRRAP_ENST00000355540.3_Silent_p.N1742N|TRRAP_ENST00000446306.3_Silent_p.N1741N	NM_001244580.1	NP_001231509.1	Q9Y4A5	TRRAP_HUMAN	transformation/transcription domain-associated protein	1760					histone deubiquitination|histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	NuA4 histone acetyltransferase complex|PCAF complex|STAGA complex|transcription factor TFTC complex	phosphotransferase activity, alcohol group as acceptor|protein binding|transcription cofactor activity			NS(3)|breast(1)|central_nervous_system(10)|endometrium(16)|kidney(7)|large_intestine(36)|liver(1)|lung(54)|ovary(10)|pancreas(1)|prostate(8)|skin(16)|stomach(5)|upper_aerodigestive_tract(6)|urinary_tract(2)	176	all_cancers(62;6.96e-09)|all_epithelial(64;4.86e-09)|Lung NSC(181;0.01)|all_lung(186;0.016)|Esophageal squamous(72;0.0274)		STAD - Stomach adenocarcinoma(171;0.215)			TAGACTTCAACGACCCCAACT	0.428000													42	58					0	0	1	0	0
ZBTB20	26137	broad.mit.edu	37	3	114069124	114069124	+	Missense_Mutation	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr3:114069124T>C	ENST00000462705.1	-	11	2403	c.1582A>G	c.(1582-1584)Aca>Gca	p.T528A	ZBTB20_ENST00000464560.1_Missense_Mutation_p.T528A|ZBTB20_ENST00000474710.1_Missense_Mutation_p.T601A|ZBTB20_ENST00000393785.2_Missense_Mutation_p.T528A|ZBTB20_ENST00000357258.3_Missense_Mutation_p.T528A|ZBTB20_ENST00000471418.1_Missense_Mutation_p.T528A|ZBTB20_ENST00000481632.1_Missense_Mutation_p.T528A	NM_001164343.1	NP_001157815.1	Q9HC78	ZBT20_HUMAN	zinc finger and BTB domain containing 20	601					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|central_nervous_system(1)|endometrium(10)|kidney(2)|large_intestine(8)|lung(15)|ovary(4)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	48				LUSC - Lung squamous cell carcinoma(41;0.0581)|Lung(219;0.191)		CACTCACCTGTGTGTACGAAC	0.547000													18	165					0	0	1	0	0
CBLB	868	broad.mit.edu	37	3	105452941	105452941	+	Missense_Mutation	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr3:105452941A>G	ENST00000264122.4	-	9	1436	c.1115T>C	c.(1114-1116)cTc>cCc	p.L372P	CBLB_ENST00000394027.3_Missense_Mutation_p.L394P|CBLB_ENST00000545639.1_3'UTR|CBLB_ENST00000405772.1_Missense_Mutation_p.L372P|CBLB_ENST00000403724.1_Missense_Mutation_p.L372P	NM_170662.3	NP_733762.2	Q13191	CBLB_HUMAN	Cbl proto-oncogene B, E3 ubiquitin protein ligase	372	Linker.				cell surface receptor linked signaling pathway|NLS-bearing substrate import into nucleus	cytoplasm|nucleus	calcium ion binding|ligase activity|signal transducer activity|zinc ion binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(8)|liver(1)|lung(20)|ovary(3)|prostate(1)|skin(3)|stomach(2)|urinary_tract(2)	49						AATCTTACAGAGCTGAAAAGT	0.398000			Mis S		AML								20	52					0	0	1	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr2:209113112C>T	ENST00000415913.1	-	4	776	c.395G>A	c.(394-396)cGt>cAt	p.R132H	IDH1_ENST00000446179.1_Missense_Mutation_p.R132H|IDH1_ENST00000345146.2_Missense_Mutation_p.R132H			O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132			R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).|R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2774)|p.R132L(59)|p.R132V(1)|p.G131_R132>VL(1)		NS(1)|autonomic_ganglia(2)|biliary_tract(24)|bone(237)|central_nervous_system(3764)|endometrium(3)|haematopoietic_and_lymphoid_tissue(794)|kidney(2)|large_intestine(7)|lung(7)|prostate(6)|skin(5)|soft_tissue(12)|thyroid(22)|urinary_tract(1)	4887				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma								34	41					0	0	1	0	0
NBR1	4077	broad.mit.edu	37	17	41352482	41352482	+	Silent	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr17:41352482A>G	ENST00000422280.1	+	17	2784	c.2325A>G	c.(2323-2325)gaA>gaG	p.E775E	NBR1_ENST00000341165.6_Silent_p.E775E|NBR1_ENST00000389312.4_Silent_p.E775E|NBR1_ENST00000590996.1_Silent_p.E775E|NBR1_ENST00000589872.1_Silent_p.E775E|NBR1_ENST00000542611.1_Silent_p.E754E	NM_031858.2	NP_114064.1	Q14596	NBR1_HUMAN	neighbor of BRCA1 gene 1	775					macroautophagy|protein oligomerization	autophagic vacuole|cytoplasmic vesicle|cytosol|late endosome|lysosome|sarcomere	ubiquitin binding|zinc ion binding			NS(1)|breast(1)|cervix(1)|kidney(4)|large_intestine(1)|lung(7)|skin(2)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(3)	24		Breast(137;0.00086)		BRCA - Breast invasive adenocarcinoma(366;0.0934)		CTGGGCAGGAACCAGCTGAGG	0.617000													21	19					0	0	1	0	0
KIF1B	23095	broad.mit.edu	37	1	10386358	10386358	+	Silent	SNP	C	C	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr1:10386358C>G	ENST00000377086.1	+	27	3067	c.2865C>G	c.(2863-2865)ctC>ctG	p.L955L	KIF1B_ENST00000377081.1_Silent_p.L955L|KIF1B_ENST00000263934.6_Silent_p.L909L			O60333	KIF1B_HUMAN	kinesin family member 1B	955					anterograde axon cargo transport|apoptosis|neuromuscular synaptic transmission|neuron-neuron synaptic transmission	cytoplasmic vesicle membrane|microtubule|microtubule associated complex|mitochondrion	ATP binding|ATPase activity|kinesin binding|microtubule motor activity|protein binding			breast(2)|endometrium(7)|kidney(8)|large_intestine(9)|lung(29)|ovary(3)|prostate(3)|skin(5)|stomach(3)|upper_aerodigestive_tract(2)	71	Ovarian(185;0.203)	all_lung(284;1.31e-05)|Lung NSC(185;2.2e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.0228)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0259)|Colorectal(212;9.79e-07)|COAD - Colon adenocarcinoma(227;0.000143)|BRCA - Breast invasive adenocarcinoma(304;0.000413)|Kidney(185;0.00134)|KIRC - Kidney renal clear cell carcinoma(229;0.0037)|STAD - Stomach adenocarcinoma(132;0.0113)|READ - Rectum adenocarcinoma(331;0.0642)		GATCAGATCTCTTCAGTGACG	0.532000													56	16					0	0	1	0	0
UPK3B	80761	broad.mit.edu	37	7	76141108	76141108	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr7:76141108G>A	ENST00000419923.2	+	2	760	c.535G>A	c.(535-537)Gga>Aga	p.G179R	UPK3B_ENST00000443097.2_Missense_Mutation_p.G124R|UPK3B_ENST00000448265.3_Missense_Mutation_p.G179R|UPK3B_ENST00000334348.3_Missense_Mutation_p.G124R|UPK3B_ENST00000394849.1_Missense_Mutation_p.G124R|UPK3B_ENST00000257632.5_Missense_Mutation_p.G179R			Q9BT76	UPK3B_HUMAN	uroplakin 3B	179					negative regulation of gene expression	integral to membrane|plasma membrane				breast(1)|central_nervous_system(2)|kidney(1)|large_intestine(1)|lung(1)|skin(2)	8		Myeloproliferative disorder(862;0.204)				GGCGGGCAGCGGAGGCGCCCC	0.706000													5	8					0	0	1	0	0
FBXO15	201456	broad.mit.edu	37	18	71740936	71740936	+	Silent	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr18:71740936C>T	ENST00000269500.5	-	10	1400	c.1065G>A	c.(1063-1065)ttG>ttA	p.L355L	FBXO15_ENST00000580806.1_5'UTR|FBXO15_ENST00000419743.2_Silent_p.L431L	NM_152676.2	NP_689889.1	Q8NCQ5	FBX15_HUMAN	F-box protein 15	355										autonomic_ganglia(1)|endometrium(3)|kidney(1)|large_intestine(7)|lung(8)|ovary(2)|pancreas(1)|skin(2)|upper_aerodigestive_tract(2)	27		Esophageal squamous(42;0.103)|Prostate(75;0.173)		BRCA - Breast invasive adenocarcinoma(31;0.143)		CATGTTCATCCAAAAGAGTTA	0.453000													22	199					0	0	1	0	0
PURB	5814	broad.mit.edu	37	7	44924342	44924342	+	Silent	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr7:44924342G>A	ENST00000395699.2	-	1	618	c.606C>T	c.(604-606)ggC>ggT	p.G202G		NM_033224.3	NP_150093.1	Q96QR8	PURB_HUMAN	purine-rich element binding protein B	202	Gly-rich.				regulation of myeloid cell differentiation	DNA replication factor A complex	mRNA binding|single-stranded DNA binding|transcription factor binding	p.G202G(1)		large_intestine(2)|lung(3)|prostate(1)|skin(1)	7						ctcccgggccgccTGCCAGCT	0.701000													11	54					0	0	1	0	0
THRA	7067	broad.mit.edu	37	17	38240101	38240101	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr17:38240101G>A	ENST00000450525.2	+	5	727	c.236G>A	c.(235-237)cGc>cAc	p.R79H	THRA_ENST00000264637.4_Missense_Mutation_p.R79H|THRA_ENST00000394121.4_Missense_Mutation_p.R79H|THRA_ENST00000584985.1_Missense_Mutation_p.R79H|THRA_ENST00000546243.1_Missense_Mutation_p.R79H	NM_199334.3	NP_955366.1	P10827	THA_HUMAN	thyroid hormone receptor, alpha	79					negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of transcription initiation, DNA-dependent|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|transcription from RNA polymerase II promoter	cytosol|nucleoplasm	protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|TBP-class protein binding|thyroid hormone binding|thyroid hormone receptor activity|transcription regulatory region DNA binding|zinc ion binding	p.R79H(2)		endometrium(1)|kidney(3)|large_intestine(2)|lung(4)|prostate(1)	11	Colorectal(19;0.000442)	Myeloproliferative disorder(1115;0.0255)			Levothyroxine(DB00451)|Liothyronine(DB00279)	TTCTTTCGCCGCACAATCCAG	0.547000													5	139					0	0	1	0	0
FUT8	2530	broad.mit.edu	37	14	66083061	66083061	+	Missense_Mutation	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr14:66083061A>G	ENST00000360689.5	+	5	2179	c.452A>G	c.(451-453)gAa>gGa	p.E151G	FUT8_ENST00000394586.2_Missense_Mutation_p.E151G|FUT8_ENST00000394585.1_Missense_Mutation_p.E151G|FUT8_ENST00000557164.1_5'UTR|FUT8_ENST00000358307.2_5'UTR	NM_004480.4|NM_178155.2	NP_004471.4|NP_835368.1	Q9BYC5	FUT8_HUMAN	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	151					in utero embryonic development|L-fucose catabolic process|N-glycan processing|oligosaccharide biosynthetic process|post-translational protein modification|protein glycosylation in Golgi|protein N-linked glycosylation via asparagine	Golgi cisterna membrane|integral to membrane	glycoprotein 6-alpha-L-fucosyltransferase activity|SH3 domain binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(12)|ovary(1)|prostate(2)|stomach(1)|upper_aerodigestive_tract(2)	22				all cancers(60;0.00109)|OV - Ovarian serous cystadenocarcinoma(108;0.00242)|BRCA - Breast invasive adenocarcinoma(234;0.0114)		CATGCAGATGAATTTCTTTTG	0.323000													5	113					0	0	1	0	0
MEF2B	100271849	broad.mit.edu	37	19	19260143	19260143	+	Silent	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:19260143G>A	ENST00000602424.2	-	5	876	c.150C>T	c.(148-150)agC>agT	p.S50S	MEF2BNB-MEF2B_ENST00000602276.1_5'UTR|MEF2B_ENST00000409224.1_Silent_p.S50S|MEF2BNB-MEF2B_ENST00000444486.3_Silent_p.S50S|MEF2B_ENST00000410050.1_Silent_p.S50S|MEF2B_ENST00000162023.5_Silent_p.S50S|MEF2B_ENST00000424583.2_Silent_p.S50S|MEF2BNB-MEF2B_ENST00000514819.3_Silent_p.S67S|MEF2B_ENST00000409447.2_Silent_p.S50S	NM_005919.3	NP_005910.1			myocyte enhancer factor 2B											breast(1)|haematopoietic_and_lymphoid_tissue(21)|large_intestine(1)|lung(2)|skin(1)|upper_aerodigestive_tract(2)	28			OV - Ovarian serous cystadenocarcinoma(5;0.00011)|Epithelial(12;0.00412)			GGCGGTTGGCGCTGTTGAAGA	0.567000													21	35					0	0	1	0	0
ELAVL1	1994	broad.mit.edu	37	19	8038658	8038658	+	Silent	SNP	A	A	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:8038658A>G	ENST00000407627.2	-	4	510	c.381T>C	c.(379-381)tcT>tcC	p.S127S	ELAVL1_ENST00000596459.1_Silent_p.S127S|ELAVL1_ENST00000351593.5_Silent_p.S154S|ELAVL1_ENST00000593807.1_Silent_p.S127S	NM_001419.2	NP_001410.2	Q15717	ELAV1_HUMAN	ELAV like RNA binding protein 1	127	RRM 2.				3'-UTR-mediated mRNA stabilization|multicellular organismal development	cytoplasm|nucleoplasm	identical protein binding|mRNA binding|nucleotide binding			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(5)|lung(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	20						GCCCAAACCGAGAGAACATGT	0.602000													12	69					0	0	1	0	0
RYR2	6262	broad.mit.edu	37	1	237863644	237863644	+	Missense_Mutation	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr1:237863644C>T	ENST00000366574.2	+	65	9561	c.9244C>T	c.(9244-9246)Cac>Tac	p.H3082Y	RYR2_ENST00000360064.6_Missense_Mutation_p.H3080Y|RYR2_ENST00000542537.1_Missense_Mutation_p.H3066Y	NM_001035.2	NP_001026.2	Q92736	RYR2_HUMAN	ryanodine receptor 2 (cardiac)	3082					cardiac muscle contraction|detection of calcium ion|induction of apoptosis by ionic changes|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|response to caffeine|response to hypoxia|response to redox state	calcium channel complex|cytosol|plasma membrane|plasma membrane enriched fraction|sarcoplasmic reticulum membrane	calcium ion binding|calmodulin binding|identical protein binding|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|receptor activity|ryanodine-sensitive calcium-release channel activity|suramin binding	p.H3080N(1)		NS(4)|breast(8)|central_nervous_system(11)|cervix(2)|endometrium(39)|haematopoietic_and_lymphoid_tissue(5)|kidney(17)|large_intestine(83)|liver(4)|lung(353)|ovary(18)|pancreas(5)|prostate(12)|skin(8)|stomach(1)|upper_aerodigestive_tract(12)|urinary_tract(4)	586	Ovarian(103;0.103)	all_cancers(173;0.000368)|Melanoma(53;0.0179)|all_epithelial(177;0.0225)	OV - Ovarian serous cystadenocarcinoma(106;0.00606)			CCAGTTCACTCACACCCGAAA	0.493000													6	3					0	0	1	0	0
USP11	8237	broad.mit.edu	37	X	47107222	47107222	+	Missense_Mutation	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chrX:47107222C>T	ENST00000377107.2	+	21	3010	c.2656C>T	c.(2656-2658)Cgc>Tgc	p.R886C	USP11_ENST00000218348.3_Missense_Mutation_p.R929C			P51784	UBP11_HUMAN	ubiquitin specific peptidase 11	929					protein deubiquitination|ubiquitin-dependent protein catabolic process	cytoplasm|nucleus	cysteine-type endopeptidase activity|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			breast(2)|central_nervous_system(2)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(9)|lung(14)|ovary(3)|pancreas(1)|stomach(1)	40						CTTCTACCAACGCCAGGACGT	0.637000													33	61					0	0	1	0	0
ZNF662	389114	broad.mit.edu	37	3	42956752	42956752	+	Missense_Mutation	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr3:42956752C>T	ENST00000541208.1	+	5	1556	c.1187C>T	c.(1186-1188)gCc>gTc	p.A396V	ZNF662_ENST00000440367.2_Missense_Mutation_p.A396V|ZNF662_ENST00000422021.1_Intron|ZNF662_ENST00000328199.6_Missense_Mutation_p.A422V|KRBOX1_ENST00000426937.1_Intron			Q6ZS27	ZN662_HUMAN	zinc finger protein 662	396					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|endometrium(1)|large_intestine(6)|lung(5)|upper_aerodigestive_tract(1)	15				KIRC - Kidney renal clear cell carcinoma(284;0.217)		TGTGGGAAGGCCTTCAGTCAG	0.428000													6	66					0	0	1	0	0
NBEAL1	65065	broad.mit.edu	37	2	204001498	204001498	+	Splice_Site	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr2:204001498G>A	ENST00000449802.1	+	28	4811		c.e28+1			NM_001114132.1	NP_001107604.1	Q6ZS30	NBEL1_HUMAN	neurobeachin-like 1								binding			NS(1)|breast(3)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(8)|liver(1)|lung(8)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	37						TAAAACTAACGTAAGCATTTA	0.348000													5	95					0	0	1	0	0
OR1D5	8386	broad.mit.edu	37	17	2966516	2966516	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr17:2966516G>A	ENST00000575751.1	-	1	385	c.386C>T	c.(385-387)cCc>cTc	p.P129L		NM_014566.1	NP_055381.1	P58170	OR1D5_HUMAN	olfactory receptor, family 1, subfamily D, member 5	129					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			kidney(1)|lung(10)	11						ATAGTGGAGGGGGCAGCAGGT	0.587000													9	49					0	0	1	0	0
DCST1	149095	broad.mit.edu	37	1	155014235	155014235	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr1:155014235G>A	ENST00000295542.1	+	8	890	c.794G>A	c.(793-795)cGc>cAc	p.R265H	DCST1_ENST00000392480.1_Missense_Mutation_p.R265H|DCST1_ENST00000368419.2_Missense_Mutation_p.R265H|DCST1_ENST00000423025.2_Missense_Mutation_p.R240H	NM_152494.3	NP_689707.2	Q5T197	DCST1_HUMAN	DC-STAMP domain containing 1	265						integral to membrane	zinc ion binding			breast(2)|endometrium(4)|kidney(2)|large_intestine(3)|lung(8)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	27	all_epithelial(22;1.43e-30)|all_lung(78;6.64e-28)|all_hematologic(923;0.0359)|Hepatocellular(266;0.0877)		BRCA - Breast invasive adenocarcinoma(34;0.000434)			TGGTTTGACCGCAAGCATGAA	0.537000													4	147					0	0	1	0	0
OBSCN	84033	broad.mit.edu	37	1	228557667	228557667	+	Silent	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr1:228557667C>T	ENST00000570156.2	+	102	22937	c.22863C>T	c.(22861-22863)gcC>gcT	p.A7621A	OBSCN_ENST00000422127.1_Silent_p.A6664A|OBSCN_ENST00000366707.4_Silent_p.A4298A	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	6664	Fibronectin type-III 4.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				CCCCATTTGCCGGCGAGAGTG	0.627000													4	103					0	0	1	0	0
AQP7	364	broad.mit.edu	37	9	33385614	33385614	+	Missense_Mutation	SNP	A	A	T	rs140995428	by1000genomes	TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr9:33385614A>T	ENST00000541274.1	-	5	830	c.381T>A	c.(379-381)agT>agA	p.S127R	AQP7_ENST00000537089.1_3'UTR|AQP7_ENST00000377425.4_Intron|AQP7_ENST00000539936.1_3'UTR			O14520	AQP7_HUMAN	aquaporin 7	0					excretion|generation of precursor metabolites and energy	cell-cell junction|cytoplasm|integral to plasma membrane	glycerol channel activity|water channel activity			NS(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(4)|skin(2)|stomach(1)	17			LUSC - Lung squamous cell carcinoma(29;0.00788)	GBM - Glioblastoma multiforme(74;0.191)		CCACAGAAAAACTCAAAGGAA	0.632000													5	128					0	0	1	0	0
TBC1D4	9882	broad.mit.edu	37	13	75887015	75887015	+	Missense_Mutation	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr13:75887015T>C	ENST00000377636.3	-	13	2588	c.2242A>G	c.(2242-2244)Agg>Ggg	p.R748G	TBC1D4_ENST00000431480.2_Missense_Mutation_p.R740G|TBC1D4_ENST00000425511.1_5'UTR|TBC1D4_ENST00000377625.2_Missense_Mutation_p.R685G	NM_014832.2	NP_055647.2	O60343	TBCD4_HUMAN	TBC1 domain family, member 4	748	Ser-rich.					cytoplasm	Rab GTPase activator activity			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|large_intestine(12)|lung(18)|ovary(4)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	50		Prostate(6;0.014)|Breast(118;0.0982)		GBM - Glioblastoma multiforme(99;0.0116)		GATGAGGTCCTTTTTCTCCCT	0.502000													3	58					0	0	1	0	0
PDGFRA	5156	broad.mit.edu	37	4	55141093	55141093	+	Missense_Mutation	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr4:55141093T>C	ENST00000257290.5	+	12	2070	c.1739T>C	c.(1738-1740)cTg>cCg	p.L580P	FIP1L1_ENST00000507166.1_Splice_Site_p.L340_splice	NM_006206.4	NP_006197.1	P16234	PGFRA_HUMAN	platelet-derived growth factor receptor, alpha polypeptide	580					cardiac myofibril assembly|cell activation|luteinization|metanephric glomerular capillary formation|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|positive regulation of DNA replication|positive regulation of fibroblast proliferation|protein autophosphorylation|retina vasculature development in camera-type eye	cytoplasm|integral to plasma membrane|nucleus	ATP binding|platelet-derived growth factor alpha-receptor activity|platelet-derived growth factor binding|platelet-derived growth factor receptor binding|protein homodimerization activity|vascular endothelial growth factor receptor activity			NS(1)|autonomic_ganglia(1)|bone(1)|breast(4)|central_nervous_system(17)|cervix(1)|endometrium(4)|eye(1)|gastrointestinal_tract_(site_indeterminate)(1)|haematopoietic_and_lymphoid_tissue(22)|kidney(6)|large_intestine(26)|liver(4)|lung(48)|ovary(4)|prostate(6)|skin(11)|small_intestine(49)|soft_tissue(727)|stomach(32)|urinary_tract(1)	967	all_cancers(7;0.000425)|all_lung(4;0.000343)|Lung NSC(11;0.000467)|all_epithelial(27;0.0131)|all_neural(26;0.0209)|Glioma(25;0.08)		GBM - Glioblastoma multiforme(1;4.18e-71)|all cancers(1;4.76e-45)|LUSC - Lung squamous cell carcinoma(32;0.00256)		Becaplermin(DB00102)|Imatinib(DB00619)|Sunitinib(DB01268)	CCGATGCAGCTGCCTTATGAC	0.458000			"""Mis, O, T"""	FIP1L1	"""GIST, idiopathic hypereosinophilic syndrome, paediatric GBM"""				Gastrointestinal Stromal Tumors, Sporadic Multiple Primary;Familial Intestinal Neurofibromatosis	TSP Lung(21;0.16)			5	72					0	0	1	0	0
ITGAD	3681	broad.mit.edu	37	16	31422117	31422117	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr16:31422117G>A	ENST00000389202.2	+	12	1323	c.1274G>A	c.(1273-1275)cGc>cAc	p.R425H		NM_005353.2	NP_005344.2	Q13349	ITAD_HUMAN	integrin, alpha D	425					cell-cell adhesion|cell-matrix adhesion|immune response|integrin-mediated signaling pathway	integrin complex	receptor activity			breast(1)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(10)|liver(2)|lung(43)|ovary(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	71						GGGGCCCCCCGCTACCAGCAT	0.642000													6	112					0	0	1	0	0
MYO18B	84700	broad.mit.edu	37	22	26423239	26423239	+	Silent	SNP	C	C	T			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr22:26423239C>T	ENST00000335473.7	+	43	7549	c.7299C>T	c.(7297-7299)taC>taT	p.Y2433Y	MYO18B_ENST00000407587.2_Silent_p.Y2434Y|MYO18B_ENST00000536101.1_Silent_p.Y2433Y	NM_032608.5	NP_115997.5	Q8IUG5	MY18B_HUMAN	myosin XVIIIB	2433						nucleus|sarcomere|unconventional myosin complex	actin binding|ATP binding|motor activity			NS(2)|breast(6)|central_nervous_system(3)|endometrium(12)|haematopoietic_and_lymphoid_tissue(4)|kidney(5)|large_intestine(27)|liver(2)|lung(60)|ovary(7)|prostate(8)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(2)	146						GCCTCGACTACGAACGCAAGA	0.562000													52	125					0	0	1	0	0
OTOL1	131149	broad.mit.edu	37	3	161221128	161221128	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr3:161221128G>A	ENST00000327928.4	+	4	832	c.832G>A	c.(832-834)Ggc>Agc	p.G278S		NM_001080440.1	NP_001073909.1	A6NHN0	OTOL1_HUMAN	otolin 1	278	Collagen-like 3.					collagen				central_nervous_system(2)|kidney(2)|large_intestine(8)|lung(11)|ovary(1)|prostate(2)|skin(1)	27						AGGCAAAAGCGGCCGTAATGG	0.542000													4	20					0	0	1	0	0
SH2D3A	10045	broad.mit.edu	37	19	6755032	6755032	+	Missense_Mutation	SNP	T	T	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:6755032T>C	ENST00000245908.6	-	5	1060	c.791A>G	c.(790-792)gAg>gGg	p.E264G	SH2D3A_ENST00000599563.1_5'UTR|SH2D3A_ENST00000437152.3_Missense_Mutation_p.E142G	NM_005490.2	NP_005481.2	Q9BRG2	SH23A_HUMAN	SH2 domain containing 3A	264	Poly-Glu.				JNK cascade|small GTPase mediated signal transduction	intracellular	guanyl-nucleotide exchange factor activity|SH3/SH2 adaptor activity			breast(3)|endometrium(3)|kidney(1)|large_intestine(4)|lung(9)|skin(3)|urinary_tract(1)	24						CTCTTCCTCCTCATCCTCCTC	0.622000													8	463					0	0	1	0	0
DFNA5	1687	broad.mit.edu	37	7	24747789	24747789	+	Missense_Mutation	SNP	G	G	A			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr7:24747789G>A	ENST00000545231.1	-	9	1605	c.455C>T	c.(454-456)gCg>gTg	p.A152V	DFNA5_ENST00000419307.1_Missense_Mutation_p.A152V|DFNA5_ENST00000342947.3_Missense_Mutation_p.A316V|DFNA5_ENST00000409970.1_Missense_Mutation_p.A152V|DFNA5_ENST00000409775.3_Missense_Mutation_p.A316V			O60443	DFNA5_HUMAN	deafness, autosomal dominant 5	316					sensory perception of sound					endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(6)|ovary(1)|prostate(3)|stomach(1)	19						AAATAGGACCGCCTGGAAGAT	0.512000													3	39					0	0	1	0	0
ASH2L	9070	broad.mit.edu	37	8	37976813	37976813	+	Frame_Shift_Del	DEL	A	A	-			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr8:37976813delA	ENST00000343823.6	+	9	1188	c.879delA	c.(877-879)ggfs	p.G293fs	ASH2L_ENST00000428278.2_Frame_Shift_Del_p.G199fs|ASH2L_ENST00000545394.1_Frame_Shift_Del_p.G154fs|ASH2L_ENST00000250635.7_Frame_Shift_Del_p.G199fs|ASH2L_ENST00000521652.1_Frame_Shift_Del_p.G199fs	NM_004674.4	NP_004665.2	Q9UBL3	ASH2L_HUMAN	ash2 (absent, small, or homeotic)-like (Drosophila)	293					hemopoiesis|histone H3-K4 methylation|positive regulation of cell proliferation|regulation of transcription, DNA-dependent|response to estrogen stimulus|transcription from RNA polymerase II promoter	Set1C/COMPASS complex	metal ion binding|protein binding|transcription regulatory region DNA binding			NS(1)|endometrium(5)|kidney(2)|large_intestine(3)|lung(6)|ovary(1)|stomach(1)	19	Colorectal(12;0.000501)	Lung NSC(58;0.0295)|all_lung(54;0.0413)				GAAGCAGCGGAAAAGGACGAG	0.567													2	4	---	---	---	---					
RP11-166B2.1	0	broad.mit.edu	37	16	12027545	12027545	+	Frame_Shift_Del	DEL	G	G	-			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr16:12027545delG	ENST00000399147.4	-	4	316	c.317delC	c.(316-318)aafs	p.T106fs	RP11-166B2.1_ENST00000532936.1_Intron																lung(2)	2						TCTTTTCTTTGTGTGCATACA	0.448													7	178	---	---	---	---					
CIC	23152	broad.mit.edu	37	19	42796882	42796883	+	Frame_Shift_Ins	INS	-	-	C			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:42796882_42796883insC	ENST00000572681.2	+	15	6132_6133	c.6064_6065insC	c.(6064-6066)cccfs	p.P2022fs	CIC_ENST00000575354.2_Frame_Shift_Ins_p.P1114fs|CIC_ENST00000160740.3_Frame_Shift_Ins_p.P1113fs			Q96RK0	CIC_HUMAN	capicua transcriptional repressor	1114					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding	p.S1117fs*34(1)		autonomic_ganglia(1)|breast(5)|central_nervous_system(32)|endometrium(10)|kidney(2)|large_intestine(7)|lung(9)|ovary(7)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	82		Prostate(69;0.00682)				GCCATCCCAGGCCCCCCCAAGC	0.683			"""Mis, F, S"""		oligodendroglioma								53	41	---	---	---	---					
LIPE-AS1	0	broad.mit.edu	37	19	43057701	43057701	+	RNA	DEL	A	A	-	rs71336818		TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:43057701delA	ENST00000594688.1	+	0	1450				LIPE-AS1_ENST00000594624.2_RNA	NR_073179.1																						CAATTCCTGCaaaaaaaaaaa	0.468													2	4	---	---	---	---					
NOVA2	4858	broad.mit.edu	37	19	46476609	46476610	+	Translation_Start_Site	INS	-	-	G			TCGA-FG-A6J1-01A-11D-A31L-08	TCGA-FG-A6J1-10A-01D-A31J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	81c3188d-0dd0-4959-b16e-ff7a3f07e4a9	e6228344-5da9-4635-a757-db83c5c7939c	g.chr19:46476609_46476610insG	ENST00000263257.5	-	0	194_195					NM_002516.2	NP_002507.1	Q9UNW9	NOVA2_HUMAN	neuro-oncological ventral antigen 2							nucleus	RNA binding			endometrium(3)|large_intestine(5)|lung(13)	21		all_neural(266;0.113)|Ovarian(192;0.127)		OV - Ovarian serous cystadenocarcinoma(262;0.00245)|GBM - Glioblastoma multiforme(486;0.0782)|Epithelial(262;0.179)		TCGGGCTCCATGGGGGGGGCCT	0.762													3	3	---	---	---	---