Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HEG1	57493	broad.mit.edu	37	3	124748221	124748221	+	Missense_Mutation	SNP	A	A	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr3:124748221A>G	ENST00000311127.4	-	2	495	c.428T>C	c.(427-429)aTg>aCg	p.M143T		NM_020733.1	NP_065784.1	Q9ULI3	HEG1_HUMAN	heart development protein with EGF-like domains 1	143						extracellular region|integral to membrane	calcium ion binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(7)|lung(24)|ovary(2)|urinary_tract(4)	47						GGTCTGAACCATCACGCCCTC	0.488000													28	26					0	0	1	0	0
MCRS1	10445	broad.mit.edu	37	12	49959390	49959390	+	Silent	SNP	A	A	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:49959390A>G	ENST00000550165.1	-	5	476	c.210T>C	c.(208-210)tcT>tcC	p.S70S	MCRS1_ENST00000546244.1_5'UTR|MCRS1_ENST00000357123.4_Silent_p.S83S|MCRS1_ENST00000343810.4_Silent_p.S70S			Q96EZ8	MCRS1_HUMAN	microspherule protein 1	70	Ser-rich.				DNA recombination|DNA repair|protein modification process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|Ino80 complex|MLL1 complex|nucleolus	protein binding			breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(4)|lung(11)	23						TTGCCCGGGTAGAAGATTTTG	0.562000													65	154					0	0	1	0	0
DIS3	22894	broad.mit.edu	37	13	73345240	73345240	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr13:73345240G>A	ENST00000377767.4	-	12	1749	c.1649C>T	c.(1648-1650)tCc>tTc	p.S550F	DIS3_ENST00000377780.4_Missense_Mutation_p.S520F|DIS3_ENST00000545453.1_Missense_Mutation_p.S388F	NM_014953.3	NP_055768.3	Q9Y2L1	RRP44_HUMAN	DIS3 mitotic control homolog (S. cerevisiae)	550					CUT catabolic process|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|rRNA catabolic process|rRNA processing	cytosol|exosome (RNase complex)|nucleolus|nucleoplasm	3'-5'-exoribonuclease activity|endonuclease activity|guanyl-nucleotide exchange factor activity|protein binding|RNA binding			central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(7)|kidney(5)|large_intestine(10)|lung(6)|prostate(2)|skin(1)	35		Breast(118;0.0074)|Acute lymphoblastic leukemia(28;0.0195)		GBM - Glioblastoma multiforme(99;0.000181)		ACATTTTAAGGAACACAAGTT	0.348000										Multiple Myeloma(4;0.011)			6	36					0	0	1	0	0
C6orf211	79624	broad.mit.edu	37	6	151789765	151789765	+	Silent	SNP	A	A	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr6:151789765A>G	ENST00000367294.3	+	5	1105	c.846A>G	c.(844-846)ggA>ggG	p.G282G	C6orf211_ENST00000545879.1_Silent_p.G163G	NM_024573.1	NP_078849.1	Q9H993	CF211_HUMAN	chromosome 6 open reading frame 211	282							protein binding			breast(1)|cervix(1)|endometrium(1)|large_intestine(5)|lung(7)	15			BRCA - Breast invasive adenocarcinoma(37;0.183)	OV - Ovarian serous cystadenocarcinoma(155;5.27e-11)		ATTTTTATGGAAAAACAATTC	0.333000													6	90					0	0	1	0	0
EGFR	1956	broad.mit.edu	37	7	55240750	55240750	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr7:55240750G>A	ENST00000275493.2	+	17	2171	c.1994G>A	c.(1993-1995)gGc>gAc	p.G665D	EGFR_ENST00000442591.1_Intron|EGFR_ENST00000454757.2_Missense_Mutation_p.G612D|EGFR_ENST00000455089.1_Missense_Mutation_p.G620D	NM_005228.3	NP_005219.2	P00533	EGFR_HUMAN	epidermal growth factor receptor	665					activation of phospholipase A2 activity by calcium-mediated signaling|activation of phospholipase C activity|axon guidance|cell proliferation|cell-cell adhesion|negative regulation of apoptosis|negative regulation of epidermal growth factor receptor signaling pathway|ossification|positive regulation of catenin import into nucleus|positive regulation of cell migration|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|positive regulation of epithelial cell proliferation|positive regulation of MAP kinase activity|positive regulation of nitric oxide biosynthetic process|positive regulation of phosphorylation|positive regulation of protein kinase B signaling cascade|protein autophosphorylation|protein insertion into membrane|regulation of nitric-oxide synthase activity|regulation of peptidyl-tyrosine phosphorylation|response to stress|response to UV-A	basolateral plasma membrane|endoplasmic reticulum membrane|endosome|extracellular space|Golgi membrane|integral to membrane|nuclear membrane|Shc-EGFR complex	actin filament binding|ATP binding|double-stranded DNA binding|epidermal growth factor receptor activity|identical protein binding|MAP/ERK kinase kinase activity|protein heterodimerization activity|protein phosphatase binding|receptor signaling protein tyrosine kinase activity			NS(2)|adrenal_gland(5)|biliary_tract(8)|bone(3)|breast(18)|central_nervous_system(106)|endometrium(26)|eye(3)|haematopoietic_and_lymphoid_tissue(9)|kidney(11)|large_intestine(85)|liver(2)|lung(13575)|oesophagus(21)|ovary(38)|pancreas(3)|peritoneum(11)|pleura(2)|prostate(35)|salivary_gland(11)|skin(9)|small_intestine(1)|soft_tissue(4)|stomach(41)|thymus(2)|thyroid(14)|upper_aerodigestive_tract(59)|urinary_tract(6)	14110	all_cancers(1;1.57e-46)|all_epithelial(1;5.62e-37)|Lung NSC(1;9.29e-25)|all_lung(1;4.39e-23)|Esophageal squamous(2;7.55e-08)|Breast(14;0.0318)		GBM - Glioblastoma multiforme(1;0)|all cancers(1;2.19e-314)|Lung(13;4.65e-05)|LUSC - Lung squamous cell carcinoma(13;0.000168)|STAD - Stomach adenocarcinoma(5;0.00164)|Epithelial(13;0.0607)		Cetuximab(DB00002)|Erlotinib(DB00530)|Gefitinib(DB00317)|Lapatinib(DB01259)|Lidocaine(DB00281)|Panitumumab(DB01269)|Trastuzumab(DB00072)	CTGGGGATCGGCCTCTTCATG	0.652000		8	"""A, O, Mis"""		"""glioma, NSCLC"""	NSCLC			Lung Cancer, Familial Clustering of	TCGA GBM(3;<1E-08)|TSP Lung(4;<1E-08)			386	78					0	0	1	0	0
MYO15A	51168	broad.mit.edu	37	17	18023162	18023162	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr17:18023162G>A	ENST00000205890.5	+	2	1386	c.1048G>A	c.(1048-1050)Gac>Aac	p.D350N		NM_016239.3	NP_057323.3	Q9UKN7	MYO15_HUMAN	myosin XVA	350	Myosin head-like.				sensory perception of sound	cytoplasm|myosin complex|stereocilium	actin binding|ATP binding|calmodulin binding|motor activity			breast(5)|central_nervous_system(2)|endometrium(17)|kidney(3)|large_intestine(16)|lung(27)|ovary(3)|pancreas(1)|prostate(6)|skin(13)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	99	all_neural(463;0.228)					TGCGCCGTACGACGCGCCATA	0.602000													13	129					0	0	1	0	0
ZNF761	388561	broad.mit.edu	37	19	53945909	53945909	+	RNA	SNP	T	T	C	rs28727441	by1000genomes	TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr19:53945909T>C	ENST00000454407.1	+	0	55				TPM3P9_ENST00000424846.3_RNA			Q86XN6	ZN761_HUMAN	zinc finger protein 761						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(1)|kidney(2)|large_intestine(5)|lung(13)|ovary(1)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	30				GBM - Glioblastoma multiforme(134;0.00786)		ACCCTGACTCTGCCTGAGGCC	0.562000													4	59					0	0	1	0	0
VTI1A	143187	broad.mit.edu	37	10	114207166	114207166	+	Missense_Mutation	SNP	T	T	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr10:114207166T>C	ENST00000393077.2	+	1	151	c.35T>C	c.(34-36)tTc>tCc	p.F12S	VTI1A_ENST00000432306.1_Missense_Mutation_p.F12S|VTI1A_ENST00000483122.1_3'UTR	NM_145206.2	NP_660207.2	Q96AJ9	VTI1A_HUMAN	vesicle transport through interaction with t-SNAREs 1A	12					intracellular protein transport|retrograde transport, endosome to Golgi	SNARE complex	protein transporter activity|SNAP receptor activity		VTI1A/TCF7L2(8)	breast(1)|large_intestine(1)|lung(2)|ovary(1)|skin(1)	6		Colorectal(252;0.0314)|Breast(234;0.183)		Epithelial(162;0.0126)|all cancers(201;0.0487)		GAGCAGGACTTCGCGGTGCTC	0.647000			T	TCF7L2	colorectal								12	10					0	0	1	0	0
ZNF157	7712	broad.mit.edu	37	X	47270081	47270081	+	Missense_Mutation	SNP	C	C	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:47270081C>A	ENST00000377073.3	+	3	288	c.202C>A	c.(202-204)Ctc>Atc	p.L68I		NM_003446.3	NP_003437.2	P51786	ZN157_HUMAN	zinc finger protein 157	68	KRAB.				negative regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			central_nervous_system(1)|endometrium(2)|large_intestine(2)|lung(5)|upper_aerodigestive_tract(1)	11						ATTAACAGGCCTCTGCGTGGC	0.517000													3	16					0.00024832	0.000273152	1	1	0
AKAP13	11214	broad.mit.edu	37	15	86284361	86284361	+	Missense_Mutation	SNP	C	C	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr15:86284361C>A	ENST00000394518.2	+	35	7788	c.7693C>A	c.(7693-7695)Ccg>Acg	p.P2565T	AKAP13_ENST00000394510.2_Missense_Mutation_p.P810T|AKAP13_ENST00000361243.2_Missense_Mutation_p.P2569T|AKAP13_ENST00000560579.1_3'UTR	NM_001270546.1|NM_007200.3	NP_001257475.1|NP_009131.2	Q12802	AKP13_HUMAN	A kinase (PRKA) anchor protein 13	2565	Interaction with ESR1.				apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|membrane|membrane fraction|nucleus	cAMP-dependent protein kinase activity|metal ion binding|protein binding|Rho guanyl-nucleotide exchange factor activity|signal transducer activity			NS(1)|breast(2)|central_nervous_system(4)|endometrium(12)|haematopoietic_and_lymphoid_tissue(4)|kidney(13)|large_intestine(13)|liver(1)|lung(43)|ovary(1)|prostate(1)|skin(2)|urinary_tract(1)	98						CTTGTCCCGCCCGAGCTCCCT	0.627000													11	20					0.00136819	0.00144713	1	1	0
DCAF12L2	340578	broad.mit.edu	37	X	125299247	125299247	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:125299247G>A	ENST00000538699.1	-	2	741	c.661C>T	c.(661-663)Cgg>Tgg	p.R221W	DCAF12L2_ENST00000360028.2_Missense_Mutation_p.R221W	NM_001013628.2	NP_001013650.1	Q5VW00	DC122_HUMAN	DDB1 and CUL4 associated factor 12-like 2	221										NS(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(11)|lung(36)|ovary(2)|pancreas(1)|skin(2)|upper_aerodigestive_tract(3)	64						GGGTCCATCCGCCACAGAGCC	0.637000													5	76					0	0	1	0	0
ZNF557	79230	broad.mit.edu	37	19	7083503	7083503	+	Silent	SNP	C	C	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr19:7083503C>G	ENST00000414706.1	+	8	1514	c.1041C>G	c.(1039-1041)ccC>ccG	p.P347P	ZNF557_ENST00000439035.2_Silent_p.P340P|ZNF557_ENST00000252840.6_Silent_p.P347P	NM_001044387.1|NM_001044388.1|NM_024341.2	NP_001037852.1|NP_001037853.1|NP_077317.2	Q8N988	ZN557_HUMAN	zinc finger protein 557	340					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(6)|large_intestine(1)|lung(5)|ovary(1)|pancreas(1)|skin(1)|stomach(1)|urinary_tract(1)	17				Lung(535;0.179)		GAGAAAAACCCTACACATGTA	0.423000													29	52					0	0	1	0	0
MUC17	140453	broad.mit.edu	37	7	100685498	100685498	+	Missense_Mutation	SNP	G	G	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr7:100685498G>C	ENST00000306151.4	+	3	10865	c.10801G>C	c.(10801-10803)Gtt>Ctt	p.V3601L		NM_001040105.1	NP_001035194.1	Q685J3	MUC17_HUMAN	mucin 17, cell surface associated	3601	59 X approximate tandem repeats.|Ser-rich.					extracellular region|integral to membrane|plasma membrane	extracellular matrix constituent, lubricant activity			NS(3)|breast(14)|central_nervous_system(2)|cervix(2)|endometrium(27)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(28)|lung(179)|ovary(19)|pancreas(1)|prostate(13)|skin(26)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(4)	343	Lung NSC(181;0.136)|all_lung(186;0.182)					CACTCCTTCTGTTGACAGAAG	0.463000													21	149					0	0	1	0	0
BUB1	699	broad.mit.edu	37	2	111415208	111415208	+	Missense_Mutation	SNP	A	A	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr2:111415208A>T	ENST00000535254.1	-	13	1538	c.1471T>A	c.(1471-1473)Tct>Act	p.S491T	BUB1_ENST00000409311.1_Missense_Mutation_p.S511T|BUB1_ENST00000302759.6_Missense_Mutation_p.S511T	NM_001278616.1	NP_001265545.1	O43683	BUB1_HUMAN	BUB1 mitotic checkpoint serine/threonine kinase	511					apoptosis|cell division|chromosome segregation|interspecies interaction between organisms|mitotic cell cycle spindle assembly checkpoint|mitotic prometaphase|regulation of sister chromatid cohesion	condensed chromosome kinetochore|cytosol	ATP binding|protein binding|protein serine/threonine kinase activity			breast(3)|endometrium(8)|kidney(4)|large_intestine(9)|lung(18)|ovary(1)|prostate(1)|stomach(1)	45		Ovarian(717;0.0822)		BRCA - Breast invasive adenocarcinoma(221;0.0556)		CAAGCCCCAGATGACCTTACA	0.303000													8	34					0	0	1	0	0
TCN2	6948	broad.mit.edu	37	22	31018998	31018998	+	Missense_Mutation	SNP	G	G	A	rs144166182		TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr22:31018998G>A	ENST00000215838.3	+	8	1644	c.1150G>A	c.(1150-1152)Gtg>Atg	p.V384M	TCN2_ENST00000405742.3_Missense_Mutation_p.V380M|TCN2_ENST00000407817.3_Missense_Mutation_p.V357M			P20062	TCO2_HUMAN	transcobalamin II	384					cobalamin metabolic process|cobalamin transport|cobalt ion transport	extracellular space	cobalamin binding			central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(5)|lung(6)|prostate(2)|urinary_tract(1)	22					Cyanocobalamin(DB00115)|Hydroxocobalamin(DB00200)	CTTAACCTCCGTGATGGGGAA	0.557000													13	106					0	0	1	0	0
EGF	1950	broad.mit.edu	37	4	110932547	110932547	+	Nonsense_Mutation	SNP	C	C	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr4:110932547C>A	ENST00000265171.5	+	24	4005	c.3560C>A	c.(3559-3561)tCa>tAa	p.S1187*	EGF_ENST00000509793.1_Nonsense_Mutation_p.S1145*|EGF_ENST00000503392.1_Nonsense_Mutation_p.S1146*	NM_001178130.1|NM_001963.4	NP_001171601.1|NP_001954.2	P01133	EGF_HUMAN	epidermal growth factor	1187					angiogenesis|DNA replication|epidermal growth factor receptor signaling pathway|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of secretion|platelet activation|platelet degranulation|positive regulation of catenin import into nucleus|positive regulation of epidermal growth factor receptor activity|positive regulation of MAP kinase activity|positive regulation of mitosis|regulation of calcium ion import|regulation of protein localization at cell surface	integral to membrane|plasma membrane|platelet alpha granule lumen	calcium ion binding|epidermal growth factor receptor binding|growth factor activity|transmembrane receptor protein tyrosine kinase activator activity	p.S1187L(1)		breast(1)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(19)|ovary(1)|pancreas(1)|prostate(1)|skin(4)|soft_tissue(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	50		Hepatocellular(203;0.0893)		OV - Ovarian serous cystadenocarcinoma(123;9.87e-06)	Sulindac(DB00605)	TCTCTCCTATCAGCTAACCCA	0.502000													12	127					1.3612e-06	1.55971e-06	1	1	0
SYN3	8224	broad.mit.edu	37	22	32923909	32923909	+	Silent	SNP	C	C	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr22:32923909C>T	ENST00000358763.2	-	12	1556	c.1314G>A	c.(1312-1314)ccG>ccA	p.P438P	SYN3_ENST00000332840.5_Silent_p.P438P	NM_001135774.1	NP_001129246.1	O14994	SYN3_HUMAN	synapsin III	438	J; Pro-rich linker.				neurotransmitter secretion	cell junction|synaptic vesicle membrane	ATP binding|ligase activity			breast(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(15)|prostate(1)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	33						TCATACCTTGCGGAGGTGGGC	0.587000													4	12					0	0	1	0	0
IGKV5-2	0	broad.mit.edu	37	2	89197262	89197262	+	RNA	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr2:89197262G>A	ENST00000390244.2	+	0	370																											ATCTGAGGATGCTGCATATTA	0.438000													15	53					0	0	1	0	0
FAM47B	170062	broad.mit.edu	37	X	34961676	34961676	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:34961676G>A	ENST00000329357.5	+	1	764	c.728G>A	c.(727-729)cGc>cAc	p.R243H		NM_152631.2	NP_689844.2	Q8NA70	FA47B_HUMAN	family with sequence similarity 47, member B	243	Pro-rich.									breast(3)|central_nervous_system(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(13)|lung(28)|ovary(4)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)	71						CCAGAGACTCGCGCATCTCAT	0.642000													11	72					0	0	1	0	0
KCNA5	3741	broad.mit.edu	37	12	5153998	5153998	+	Missense_Mutation	SNP	C	C	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:5153998C>T	ENST00000252321.3	+	1	914	c.685C>T	c.(685-687)Cgc>Tgc	p.R229C		NM_002234.3	NP_002225.2	P22460	KCNA5_HUMAN	potassium voltage-gated channel, shaker-related subfamily, member 5	229						Golgi apparatus|voltage-gated potassium channel complex	delayed rectifier potassium channel activity			NS(1)|breast(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(8)|liver(1)|lung(21)|ovary(5)|prostate(2)|upper_aerodigestive_tract(2)	52						GCCCCTGCCCCGCAACGAGTT	0.607000													14	94					0	0	1	0	0
DPY19L2P2	0	broad.mit.edu	37	7	102912190	102912190	+	RNA	SNP	T	T	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr7:102912190T>G	ENST00000312132.4	-	0	2389																											TCTGGATAAATATGGAAGCGT	0.343000													3	62					0	0	1	0	0
COL16A1	1307	broad.mit.edu	37	1	32157245	32157245	+	Splice_Site	SNP	T	T	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr1:32157245T>G	ENST00000373672.3	-	18	1774		c.e18-2		COL16A1_ENST00000373668.3_Splice_Site|COL16A1_ENST00000271069.6_Splice_Site	NM_001856.3	NP_001847.3	Q07092	COGA1_HUMAN	collagen, type XVI, alpha 1						cell adhesion|female pregnancy|integrin-mediated signaling pathway	collagen type XVI	integrin binding|structural molecule activity			breast(4)|central_nervous_system(2)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(7)|lung(15)|ovary(8)|prostate(4)	48		Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0423)|all_neural(195;0.0837)|Breast(348;0.116)		STAD - Stomach adenocarcinoma(196;0.059)		TGGCCGGCCCTGTGGGGGGAT	0.652000													5	40					0	0	1	0	0
KIF26B	55083	broad.mit.edu	37	1	245849237	245849237	+	Silent	SNP	C	C	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr1:245849237C>T	ENST00000366518.4	+	9	1913	c.1809C>T	c.(1807-1809)tcC>tcT	p.S603S	KIF26B_ENST00000407071.2_Silent_p.S984S			Q2KJY2	KI26B_HUMAN	kinesin family member 26B	984	Kinesin-motor.				microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity	p.S984S(2)		breast(1)|central_nervous_system(2)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(21)|ovary(4)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	51	all_cancers(71;3.86e-05)|all_epithelial(71;0.000121)|Ovarian(71;0.0412)|all_lung(81;0.0498)|Lung NSC(105;0.0708)|Breast(184;0.127)		OV - Ovarian serous cystadenocarcinoma(106;0.022)			ATAATGGGTCCGAAGGTCAGC	0.622000													5	30					0	0	1	0	0
DCDC1	341019	broad.mit.edu	37	11	30926645	30926645	+	Missense_Mutation	SNP	G	G	A	rs144668195		TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr11:30926645G>A	ENST00000597505.1	-	29	4170	c.4171C>T	c.(4171-4173)Cgg>Tgg	p.R1391W	DCDC1_ENST00000339794.5_Missense_Mutation_p.R470W|DCDC1_ENST00000406071.2_Missense_Mutation_p.R126W			P59894	DCDC1_HUMAN	doublecortin domain containing 1	153					intracellular signal transduction					central_nervous_system(1)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(4)|lung(17)|pancreas(2)|prostate(1)|skin(1)|stomach(1)	31	Lung SC(675;0.225)					GTCTTCATCCGTAAAGACAAT	0.403000													4	44					0	0	1	0	0
TLR7	51284	broad.mit.edu	37	X	12905054	12905054	+	Missense_Mutation	SNP	G	G	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:12905054G>C	ENST00000380659.3	+	3	1566	c.1427G>C	c.(1426-1428)aGa>aCa	p.R476T		NM_016562.3	NP_057646.1	Q9NYK1	TLR7_HUMAN	toll-like receptor 7	476					cellular response to mechanical stimulus|defense response to virus|I-kappaB phosphorylation|inflammatory response|innate immune response|positive regulation of chemokine production|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of interferon-gamma biosynthetic process|positive regulation of interleukin-8 biosynthetic process|positive regulation of interleukin-8 production|positive regulation of NF-kappaB import into nucleus	early phagosome|endoplasmic reticulum membrane|endosome membrane|integral to membrane|lysosome|plasma membrane	double-stranded RNA binding|single-stranded RNA binding|siRNA binding|transmembrane receptor activity			NS(1)|breast(4)|endometrium(5)|kidney(1)|large_intestine(8)|lung(18)|ovary(2)|pancreas(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	44					Imiquimod(DB00724)	AGGAGTTGCAGATTCAAAAAC	0.368000													39	101					0	0	1	0	0
CASP4	837	broad.mit.edu	37	11	104815486	104815486	+	Silent	SNP	G	G	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr11:104815486G>T	ENST00000444739.2	-	8	2038	c.1128C>A	c.(1126-1128)ggC>ggA	p.G376G	CASP4_ENST00000393150.3_Silent_p.G320G	NM_001225.3	NP_001216.1	P49662	CASP4_HUMAN	caspase 4, apoptosis-related cysteine peptidase	376					apoptosis|induction of apoptosis|proteolysis	intracellular	cysteine-type endopeptidase activity|protein binding			central_nervous_system(1)|endometrium(2)|large_intestine(5)|lung(11)|ovary(1)|skin(1)|urinary_tract(2)	23		Acute lymphoblastic leukemia(157;0.000967)|all_hematologic(158;0.0017)|Melanoma(852;0.0047)		BRCA - Breast invasive adenocarcinoma(274;0.000854)|Epithelial(105;0.00879)|all cancers(92;0.0357)		ATTTTCAATTGCCAGGAAAGA	0.383000													8	36					0.000978159	0.00105488	1	1	0
CLSTN3	9746	broad.mit.edu	37	12	7295599	7295599	+	Missense_Mutation	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:7295599G>A	ENST00000537408.1	+	10	2249	c.1711G>A	c.(1711-1713)Gag>Aag	p.E571K	CLSTN3_ENST00000266546.6_Missense_Mutation_p.E559K			Q9BQT9	CSTN3_HUMAN	calsyntenin 3	559					homophilic cell adhesion	endoplasmic reticulum membrane|Golgi membrane|integral to membrane|plasma membrane	calcium ion binding			NS(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(7)|prostate(1)|skin(1)	33						TAGGGATTTCGAGAGCCTGGG	0.612000													15	32					0	0	1	0	0
TMCO3	55002	broad.mit.edu	37	13	114149982	114149982	+	Missense_Mutation	SNP	C	C	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr13:114149982C>T	ENST00000434316.2	+	2	445	c.86C>T	c.(85-87)gCg>gTg	p.A29V	TMCO3_ENST00000375391.1_Missense_Mutation_p.A29V|TMCO3_ENST00000474393.1_3'UTR	NM_017905.4	NP_060375.4	Q6UWJ1	TMCO3_HUMAN	transmembrane and coiled-coil domains 3	29						integral to membrane	solute:hydrogen antiporter activity			NS(1)|endometrium(4)|large_intestine(9)|liver(1)|lung(8)|prostate(1)|stomach(1)	25	Lung NSC(43;0.0161)|all_neural(89;0.0337)|Hepatocellular(20;0.0877)|Medulloblastoma(90;0.163)|Lung SC(71;0.218)	all_cancers(25;0.0145)|all_epithelial(44;0.00286)|all_lung(25;0.0273)|Breast(118;0.0411)|Lung NSC(25;0.0983)	all cancers(43;0.0317)			GAGGAGGTGGCGCAGCGTGTG	0.647000													16	19					0	0	1	0	0
TVP23B	51030	broad.mit.edu	37	17	18692723	18692723	+	Missense_Mutation	SNP	A	A	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr17:18692723A>G	ENST00000307767.8	+	2	369	c.70A>G	c.(70-72)Aat>Gat	p.N24D	TVP23B_ENST00000581733.1_5'UTR|TVP23B_ENST00000476139.1_5'UTR|TVP23B_ENST00000574226.1_Missense_Mutation_p.N24D	NM_016078.4	NP_057162.4			trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)																		GGAGACGACTAATAGACCAAG	0.413000													19	69					0	0	1	0	0
GOLGA6C	653641	broad.mit.edu	37	15	75562493	75562493	+	Missense_Mutation	SNP	C	C	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr15:75562493C>A	ENST00000300576.5	+	18	2035	c.2035C>A	c.(2035-2037)Ccg>Acg	p.P679T		NM_001164404.1	NP_001157876.1	A6NDK9	GOG6C_HUMAN	golgin A6 family, member C	679										ovary(1)	1						TGACAACCCCCCGGTACAGCA	0.602000													6	142					3.59834e-05	4.03895e-05	1	1	0
CUX2	23316	broad.mit.edu	37	12	111758084	111758084	+	Silent	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:111758084G>A	ENST00000261726.6	+	17	2425	c.2271G>A	c.(2269-2271)gcG>gcA	p.A757A		NM_015267.3	NP_056082.2	O14529	CUX2_HUMAN	cut-like homeobox 2	757						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|large_intestine(9)|lung(24)|ovary(5)|prostate(4)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	55						CCGCGCAGGCGCCGCTCCCGG	0.736000													3	14					0	0	1	0	0
HHIPL1	84439	broad.mit.edu	37	14	100123456	100123456	+	Missense_Mutation	SNP	G	G	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr14:100123456G>T	ENST00000330710.5	+	3	1120	c.1022G>T	c.(1021-1023)gGg>gTg	p.G341V	HHIPL1_ENST00000357223.2_Missense_Mutation_p.G341V	NM_001127258.1	NP_001120730.1	Q96JK4	HIPL1_HUMAN	HHIP-like 1	341					carbohydrate metabolic process	extracellular region|membrane	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor|quinone binding|scavenger receptor activity			breast(1)|endometrium(2)|large_intestine(2)|lung(8)|skin(2)	15		Melanoma(154;0.128)				GACCCCTTTGGGACATTTGGA	0.532000													68	169					1.7488e-33	2.04646e-33	1	1	0
ARHGEF1	0	broad.mit.edu	37	19	42396888	42396888	+	Silent	SNP	G	G	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr19:42396888G>A	ENST00000599846.1	+	7	707	c.582G>A	c.(580-582)gcG>gcA	p.A194A	ARHGEF1_ENST00000337665.4_Silent_p.A209A|ARHGEF1_ENST00000347545.4_Silent_p.A161A|ARHGEF1_ENST00000354532.3_Silent_p.A194A|ARHGEF1_ENST00000378152.4_Silent_p.A176A			Q92888	ARHG1_HUMAN	Rho guanine nucleotide exchange factor (GEF) 1	194	RGSL.				cell proliferation|negative regulation of axonogenesis|nerve growth factor receptor signaling pathway|positive regulation of axonogenesis|regulation of Rho protein signal transduction|Rho protein signal transduction	cytosol|plasma membrane	GTPase activator activity|protein binding|Rho guanyl-nucleotide exchange factor activity			breast(2)|endometrium(8)|large_intestine(6)|lung(9)|ovary(3)|prostate(1)|skin(4)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	37		Renal(1328;0.000518)|Hepatocellular(1079;0.0046)|Medulloblastoma(540;0.0425)		Epithelial(262;5.89e-46)|GBM - Glioblastoma multiforme(1328;2.49e-12)|STAD - Stomach adenocarcinoma(1328;0.00644)		GGCACGTGGCGGAGCGGCTGC	0.706000													7	13					0	0	1	0	0
ZSCAN1	284312	broad.mit.edu	37	19	58549469	58549469	+	Missense_Mutation	SNP	G	G	A	rs148253808		TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr19:58549469G>A	ENST00000282326.1	+	3	512	c.265G>A	c.(265-267)Gcg>Acg	p.A89T	ZSCAN1_ENST00000601162.1_Missense_Mutation_p.A89T|ZSCAN1_ENST00000391700.1_Missense_Mutation_p.A89T	NM_182572.3	NP_872378.3	Q8NBB4	ZSCA1_HUMAN	zinc finger and SCAN domain containing 1	89	SCAN box.				viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.A89T(1)		NS(1)|breast(3)|central_nervous_system(2)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(5)|lung(25)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	48		Colorectal(82;5.46e-05)|all_neural(62;0.0182)|Breast(46;0.0389)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0152)		GTTCCTGGGCGCGCTGCCCAG	0.692000													11	13					0	0	1	0	0
SLC26A4	5172	broad.mit.edu	37	7	107355878	107355878	+	Missense_Mutation	SNP	C	C	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr7:107355878C>G	ENST00000265715.3	+	21	2554	c.2330C>G	c.(2329-2331)aCa>aGa	p.T777R	SLC26A4_ENST00000544569.1_Missense_Mutation_p.T364R|SLC26A4_ENST00000541474.1_Missense_Mutation_p.T338R|SLC26A4_ENST00000543100.1_Missense_Mutation_p.T346R	NM_000441.1	NP_000432.1	O43511	S26A4_HUMAN	solute carrier family 26 (anion exchanger), member 4	777					regulation of pH|regulation of protein localization|sensory perception of sound	apical plasma membrane|integral to membrane	chloride transmembrane transporter activity|inorganic anion exchanger activity|iodide transmembrane transporter activity|secondary active sulfate transmembrane transporter activity			central_nervous_system(2)|endometrium(1)|kidney(5)|large_intestine(8)|lung(16)|ovary(3)|prostate(1)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(2)	46						GCTATGCGTACACTTGCATCC	0.373000									Pendred syndrome				5	143					0	0	1	0	0
GOLGA6C	653641	broad.mit.edu	37	15	75562495	75562495	+	Silent	SNP	G	G	T	rs138154232	by1000genomes	TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr15:75562495G>T	ENST00000300576.5	+	18	2037	c.2037G>T	c.(2035-2037)ccG>ccT	p.P679P		NM_001164404.1	NP_001157876.1	A6NDK9	GOG6C_HUMAN	golgin A6 family, member C	679										ovary(1)	1						ACAACCCCCCGGTACAGCAGA	0.602000													6	144					0.0215528	0.0215528	1	1	0
KIFAP3	22920	broad.mit.edu	37	1	169985738	169985738	+	Missense_Mutation	SNP	C	C	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr1:169985738C>G	ENST00000367765.1	-	10	2429	c.928G>C	c.(928-930)Gtg>Ctg	p.V310L	KIFAP3_ENST00000361580.2_Missense_Mutation_p.V350L|KIFAP3_ENST00000367767.1_Missense_Mutation_p.V306L|KIFAP3_ENST00000540905.1_Missense_Mutation_p.V52L|KIFAP3_ENST00000538366.1_Missense_Mutation_p.V272L	NM_001204517.1	NP_001191446.1	Q92845	KIFA3_HUMAN	kinesin-associated protein 3	350					blood coagulation|plus-end-directed vesicle transport along microtubule|protein complex assembly|signal transduction	centrosome|condensed nuclear chromosome|cytosol|endoplasmic reticulum|kinesin II complex|spindle microtubule	kinesin binding			endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(18)|prostate(2)|skin(3)|urinary_tract(2)	35	all_hematologic(923;0.0922)|Acute lymphoblastic leukemia(37;0.181)					ATCATTTTCACCAGTTTTTCA	0.328000													7	106					0	0	1	0	0
SOWAHB	345079	broad.mit.edu	37	4	77817817	77817817	+	Missense_Mutation	SNP	C	C	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr4:77817817C>G	ENST00000334306.2	-	1	1185	c.1186G>C	c.(1186-1188)Gac>Cac	p.D396H		NM_001029870.1	NP_001025041.1	A6NEL2	ANR56_HUMAN	sosondowah ankyrin repeat domain family member B	396																	TCCACAAAGTCATCCAGATCT	0.572000													35	70					0	0	1	0	0
TACC2	10579	broad.mit.edu	37	10	124009064	124009064	+	Missense_Mutation	SNP	A	A	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr10:124009064A>G	ENST00000369005.1	+	22	9006	c.8666A>G	c.(8665-8667)aAt>aGt	p.N2889S	TACC2_ENST00000368999.1_Missense_Mutation_p.N979S|TACC2_ENST00000360561.3_Missense_Mutation_p.N937S|TACC2_ENST00000515603.1_Missense_Mutation_p.N2767S|TACC2_ENST00000453444.2_Missense_Mutation_p.N2816S|TACC2_ENST00000369001.1_Missense_Mutation_p.N516S|TACC2_ENST00000358010.1_Missense_Mutation_p.N1035S|TACC2_ENST00000513429.1_Missense_Mutation_p.N1035S|TACC2_ENST00000334433.3_Missense_Mutation_p.N2889S|TACC2_ENST00000369004.3_Missense_Mutation_p.N949S|TACC2_ENST00000260733.3_Missense_Mutation_p.N967S|TACC2_ENST00000515273.1_Missense_Mutation_p.N2816S|TACC2_ENST00000369000.1_Missense_Mutation_p.N512S	NM_206862.2	NP_996744.2	O95359	TACC2_HUMAN	transforming, acidic coiled-coil containing protein 2	2889						microtubule organizing center|nucleus	nuclear hormone receptor binding			NS(1)|breast(5)|central_nervous_system(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(15)|lung(27)|ovary(6)|prostate(3)|skin(8)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(3)	83		all_neural(114;0.0656)|Lung NSC(174;0.136)|all_lung(145;0.17)|Breast(234;0.197)				CGCAGGGCCAATGCTGAGATT	0.612000													13	13					0	0	1	0	0
PCDH19	57526	broad.mit.edu	37	X	99661865	99661865	+	Missense_Mutation	SNP	T	T	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:99661865T>C	ENST00000373034.4	-	1	3406	c.1731A>G	c.(1729-1731)atA>atG	p.I577M	PCDH19_ENST00000255531.7_Missense_Mutation_p.I577M|PCDH19_ENST00000420881.2_Missense_Mutation_p.I577M	NM_001184880.1	NP_001171809.1	Q8TAB3	PCD19_HUMAN	protocadherin 19	577	Cadherin 6.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			breast(5)|endometrium(11)|kidney(1)|large_intestine(14)|liver(1)|lung(23)|ovary(3)|prostate(2)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(2)	68						AGTTGCGGGGTATGTAGACCT	0.572000													4	87					0	0	1	0	0
DCAF8L1	139425	broad.mit.edu	37	X	27998163	27998163	+	Missense_Mutation	SNP	C	C	G			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:27998163C>G	ENST00000441525.1	-	1	1403	c.1289G>C	c.(1288-1290)aGa>aCa	p.R430T		NM_001017930.1	NP_001017930.1	A6NGE4	DC8L1_HUMAN	DDB1 and CUL4 associated factor 8-like 1	430										NS(1)|breast(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(10)|lung(24)|ovary(3)|prostate(1)|skin(4)|stomach(1)|urinary_tract(1)	56						CCCCTTATATCTCTTAACATA	0.458000													9	39					0	0	1	0	0
C4BPA	722	broad.mit.edu	37	1	207297295	207297295	+	Missense_Mutation	SNP	C	C	T			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr1:207297295C>T	ENST00000367070.3	+	5	651	c.457C>T	c.(457-459)Cgt>Tgt	p.R153C		NM_000715.3	NP_000706.1	P04003	C4BPA_HUMAN	complement component 4 binding protein, alpha	153	Sushi 2.				complement activation, classical pathway|innate immune response	extracellular region	protein binding			breast(1)|central_nervous_system(2)|endometrium(1)|kidney(2)|large_intestine(10)|lung(7)|ovary(2)|skin(1)|urinary_tract(2)	28						AACCACTAGTCGTTGTGAAGT	0.363000													4	39					0	0	1	0	0
RAI2	10742	broad.mit.edu	37	X	17819635	17819635	+	Missense_Mutation	SNP	G	G	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:17819635G>C	ENST00000545871.1	-	3	956	c.496C>G	c.(496-498)Ccc>Gcc	p.P166A	RAI2_ENST00000360011.1_Missense_Mutation_p.P166A|RAI2_ENST00000331511.1_Missense_Mutation_p.P166A|RAI2_ENST00000415486.3_Missense_Mutation_p.P116A|RAI2_ENST00000451717.1_Missense_Mutation_p.P166A	NM_001172739.1|NM_001172743.1	NP_001166210.1|NP_001166214.1	Q9Y5P3	RAI2_HUMAN	retinoic acid induced 2	166					embryo development					breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(7)|ovary(1)|pancreas(1)|prostate(1)	22	Hepatocellular(33;0.183)					AGGAGCTGGGGCTGGGCCTCG	0.637000													4	76					0	0	1	0	0
CACNB3	784	broad.mit.edu	37	12	49219447	49219447	+	Missense_Mutation	SNP	T	T	C			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:49219447T>C	ENST00000301050.2	+	9	836	c.637T>C	c.(637-639)Tcc>Ccc	p.S213P	CACNB3_ENST00000547392.1_Missense_Mutation_p.S186P|CACNB3_ENST00000536187.2_Missense_Mutation_p.S212P|CACNB3_ENST00000547230.1_Missense_Mutation_p.S172P|CACNB3_ENST00000540990.1_Missense_Mutation_p.S200P	NM_000725.3	NP_000716.2	P54284	CACB3_HUMAN	calcium channel, voltage-dependent, beta 3 subunit	213					axon guidance|membrane depolarization|synaptic transmission	cytosol|voltage-gated calcium channel complex	protein binding|voltage-gated calcium channel activity			autonomic_ganglia(1)|breast(1)|large_intestine(5)|lung(4)|prostate(1)	12					Verapamil(DB00661)	CCCCAGGATCTCCATCACCCG	0.562000													16	93					0	0	1	0	0
SCN9A	6335	broad.mit.edu	37	2	167056037	167056037	+	Frame_Shift_Del	DEL	T	T	-			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr2:167056037delT	ENST00000375387.4	-	27	5455	c.5115delA	c.(5113-5115)ctfs	p.L1705fs	AC010127.3_ENST00000447809.2_RNA|SCN9A_ENST00000409672.1_Frame_Shift_Del_p.L1693fs|SCN9A_ENST00000409435.1_Frame_Shift_Del_p.L1704fs|SCN9A_ENST00000303354.6_Frame_Shift_Del_p.L1705fs			Q15858	SCN9A_HUMAN	sodium channel, voltage-gated, type IX, alpha subunit	1704						voltage-gated sodium channel complex	voltage-gated sodium channel activity			NS(1)|breast(5)|central_nervous_system(6)|endometrium(6)|kidney(3)|large_intestine(27)|lung(38)|ovary(6)|prostate(8)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(2)	108					Lamotrigine(DB00555)|Lidocaine(DB00281)	GAATAGGTGCTAGCAATCCAT	0.423													12	214	---	---	---	---					
PBRM1	55193	broad.mit.edu	37	3	52610666	52610666	+	Frame_Shift_Del	DEL	G	G	-			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr3:52610666delG	ENST00000356770.4	-	21	3488	c.3486delC	c.(3484-3486)ccfs	p.P1162fs	PBRM1_ENST00000410007.1_Frame_Shift_Del_p.P1169fs|SMIM4_ENST00000476842.1_Intron|PBRM1_ENST00000394830.3_Frame_Shift_Del_p.P1169fs|PBRM1_ENST00000409767.1_Frame_Shift_Del_p.P1209fs|PBRM1_ENST00000409057.1_Frame_Shift_Del_p.P1194fs|PBRM1_ENST00000296302.7_Frame_Shift_Del_p.P1194fs|PBRM1_ENST00000409114.3_Frame_Shift_Del_p.P1209fs|PBRM1_ENST00000337303.4_Frame_Shift_Del_p.P1194fs			Q86U86	PB1_HUMAN	polybromo 1	1194	BAH 2.				chromatin remodeling|mitosis|negative regulation of cell proliferation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nuclear chromosome	chromatin binding|DNA binding|protein binding			breast(5)|endometrium(5)|kidney(301)|liver(1)|lung(22)|pancreas(1)	335				BRCA - Breast invasive adenocarcinoma(193;1.8e-05)|Kidney(197;0.00105)|KIRC - Kidney renal clear cell carcinoma(197;0.00122)|OV - Ovarian serous cystadenocarcinoma(275;0.0613)		GAATGAAGATGGGGCCATAAA	0.368			"""Mis, N, F, S, D, O"""		"""clear cell renal carcinoma, breast"""								32	40	---	---	---	---					
AC092661.1	0	broad.mit.edu	37	4	118496039	118496040	+	RNA	INS	-	-	A			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr4:118496039_118496040insA	ENST00000422145.3	+	0	159				NT5C3AP1_ENST00000441170.1_RNA																							TCTTTTTTTTTAATGGGTTAGA	0.342													4	3	---	---	---	---					
RP11-1252I4.2	0	broad.mit.edu	37	5	177398373	177398396	+	RNA	DEL	AGGACGAAGAGCTGGAGAGCGCCA	AGGACGAAGAGCTGGAGAGCGCCA	-	rs70994948		TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr5:177398373_177398396delAGGACGAAGAGCTGGAGAGCGCCA	ENST00000511650.1	+	0	145																											GTCCCCGGGGAGGACGAAGAGCTGGAGAGCGCCAAGGACGACGA	0.683													3	4	---	---	---	---					
LTB	4050	broad.mit.edu	37	6	31548718	31548718	+	Frame_Shift_Del	DEL	C	C	-			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr6:31548718delC	ENST00000429299.2	-	4	510	c.503delG	c.(502-504)gcfs	p.G168fs	LTB_ENST00000483972.1_5'UTR|LTB_ENST00000446745.2_3'UTR	NM_002341.1	NP_002332.1	Q06643	TNFC_HUMAN	lymphotoxin beta (TNF superfamily, member 3)	168					cell-cell signaling|immune response|positive regulation of interleukin-12 biosynthetic process|signal transduction	extracellular space|integral to membrane	cytokine activity|tumor necrosis factor receptor binding			haematopoietic_and_lymphoid_tissue(3)|large_intestine(2)|lung(2)|prostate(1)|upper_aerodigestive_tract(1)	9					Infliximab(DB00065)|Simvastatin(DB00641)	CCCGTAGGCGCCCCCCGCCCG	0.751													2	4	---	---	---	---					
C9orf3	84909	broad.mit.edu	37	9	97535395	97535397	+	In_Frame_Del	DEL	TTT	TTT	-	rs151071633	by1000genomes	TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr9:97535395_97535397delTTT	ENST00000375315.2	+	2	909_911	c.909_911delTTT	c.(907-912)tct>tc	p.SF303del	C9orf3_ENST00000297979.5_In_Frame_Del_p.SF303del|C9orf3_ENST00000277198.2_In_Frame_Del_p.SF303del	NM_001193329.1	NP_001180258.1	Q8N6M6	AMPO_HUMAN	chromosome 9 open reading frame 3	303					leukotriene biosynthetic process|proteolysis	cytoplasm	aminopeptidase activity|metallopeptidase activity|zinc ion binding			cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(12)|ovary(1)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	23				OV - Ovarian serous cystadenocarcinoma(323;0.000275)		CAGCTGCATCTTTTGTTGTTTTA	0.463													71	84	---	---	---	---					
MUC6	4588	broad.mit.edu	37	11	1031058	1031059	+	Splice_Site	INS	-	-	G	rs140721287	by1000genomes	TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr11:1031058_1031059insG	ENST00000421673.2	-	6	625		c.e6-2			NM_005961.2	NP_005952.2	Q6W4X9	MUC6_HUMAN	mucin 6, oligomeric mucus/gel-forming						maintenance of gastrointestinal epithelium	extracellular region	extracellular matrix structural constituent			breast(1)|central_nervous_system(1)|cervix(2)|endometrium(8)|kidney(10)|large_intestine(6)|lung(43)|ovary(4)|prostate(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	80		all_cancers(49;3.3e-08)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		all cancers(45;1.24e-24)|BRCA - Breast invasive adenocarcinoma(625;0.00031)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)		GGAACTTGCCTGGGGTGCAGAA	0.703													4	5	---	---	---	---					
CCNT1	904	broad.mit.edu	37	12	49087434	49087436	+	In_Frame_Del	DEL	ATG	ATG	-			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr12:49087434_49087436delATG	ENST00000261900.3	-	9	1783_1785	c.1561_1563delCAT	c.(1561-1563)del	p.H521del		NM_001240.3	NP_001231.2	O60563	CCNT1_HUMAN	cyclin T1	521	His-rich.				cell cycle|cell division|interspecies interaction between organisms|positive regulation of viral transcription|protein phosphorylation|regulation of cyclin-dependent protein kinase activity|regulation of transcription, DNA-dependent|transcription elongation from RNA polymerase II promoter|viral reproduction	nucleoplasm	DNA binding|protein kinase binding			breast(3)|endometrium(1)|kidney(1)|large_intestine(4)|lung(13)|ovary(3)|skin(2)	27						AGTGGTGATTATGATGATGATGA	0.443													10	404	---	---	---	---					
SOGA2	23255	broad.mit.edu	37	18	8784233	8784243	+	Frame_Shift_Del	DEL	CTGGGGCTGCG	CTGGGGCTGCG	-			TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chr18:8784233_8784243delCTGGGGCTGCG	ENST00000359865.3	+	6	1265_1275	c.1123_1133delCTGGGGCTGCG	c.(1123-1134)tfs	p.LGLR375fs	SOGA2_ENST00000517570.1_Frame_Shift_Del_p.LGLR375fs|SOGA2_ENST00000400050.3_Frame_Shift_Del_p.LGLR375fs|SOGA2_ENST00000306285.7_5'UTR|SOGA2_ENST00000306329.11_Frame_Shift_Del_p.LGLR735fs	NM_015210.3	NP_056025.2	Q9Y4B5	CC165_HUMAN	SOGA family member 2	726																	GGCAGCCCACCTGGGGCTGCGTGCCCCCAGT	0.673													7	43	---	---	---	---					
SRPX	8406	broad.mit.edu	37	X	38079976	38079978	+	In_Frame_Del	DEL	GCA	GCA	-	rs72445954		TCGA-E1-A7YQ-01A-11D-A34J-08	TCGA-E1-A7YQ-10A-01D-A34M-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a958293-774d-4cb9-ba11-59ac163cfd03	df861df9-ee5c-4f51-8f5b-cefb65965693	g.chrX:38079976_38079978delGCA	ENST00000378533.3	-	1	174_176	c.68_70delTGC	c.(67-72)cgc>c	p.LR23del	SRPX_ENST00000544439.1_In_Frame_Del_p.LR23del|SRPX_ENST00000343800.6_Intron|TM4SF2_ENST00000465127.1_Intron|SRPX_ENST00000432886.2_In_Frame_Del_p.LR23del|SRPX_ENST00000538295.1_In_Frame_Del_p.LR23del	NM_006307.4	NP_006298.1	P78539	SRPX_HUMAN	sushi-repeat containing protein, X-linked	23			Missing.		cell adhesion	cell surface|membrane		p.L23delL(2)		autonomic_ganglia(1)|breast(2)|endometrium(5)|large_intestine(5)|lung(10)|prostate(2)	25						GGCGGGACGCgcagcagcagcag	0.729											OREG0019726	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	4	---	---	---	---