Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
IGSF21	0	genome.wustl.edu	36	1	18534084	18534084	+	Silent	SNP	C	C	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	1	18534084	18534084	C	T	SNP	IGSF21	NM_032880.2	human	genbank	54_36p	+1	provisional	silent	c.417	p.N139	0.998	HMMSmart_IG,HMMPfam_V-set,superfamily_SSF48726	HMMSmart_IG,HMMPfam_V-set,superfamily_SSF48726	-	no_errors	486	9	1.82	315	252	44.37	1	0	0.00
MPL	0	genome.wustl.edu	36	1	43590992	43590992	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	1	43590992	43590992	C	G	SNP	MPL	NM_005373.2	human	genbank	54_36p	+1	reviewed	missense	c.1870	p.H624D	0.996	NULL	PatternScan_HEMATOPO_REC_L_F1,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_EpoR_lig-bind	-	no_errors	342	8	2.29	148	145	49.49	42	40	48.19
LCE1B	0	genome.wustl.edu	36	1	151051691	151051691	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	1	151051691	151051691	G	T	SNP	LCE1B	NM_178349.1	human	genbank	54_36p	+1	validated	nonsense	c.145	p.G49*	0.991	NULL	NULL	-	no_errors	70	2	2.78	91	67	41.88	NA	NA	NA
LAMC1	0	genome.wustl.edu	36	1	181352534	181352534	+	Silent	SNP	T	T	C			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	1	181352534	181352534	T	C	SNP	LAMC1	NM_002293.3	human	genbank	54_36p	+1	reviewed	silent	c.1437	p.P479	1.000	HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,PatternScan_EGF_LAM_1,superfamily_Grow_fac_recept,superfamily_SSF57196	HMMPfam_Laminin_B,HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,PatternScan_EGF_LAM_1,HMMPfam_Laminin_N,HMMSmart_LamNT,superfamily_Grow_fac_recept,PatternScan_EGF_1,PatternScan_EGF_2,HMMSmart_LamB,superfamily_SSF57196	-	no_errors	196	0	0.00	195	167	46.13	1	0	0.00
STK36	0	genome.wustl.edu	36	2	219271843	219271843	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	2	219271843	219271843	A	G	SNP	STK36	NM_015690.3	human	genbank	54_36p	+1	validated	missense	c.3332	p.Y1111C	1.000	superfamily_ARM repeat	HMMPfam_HEAT,HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),superfamily_ARM repeat,PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase	-	no_errors	331	2	0.60	175	140	44.44	1	6	85.71
TET2	0	genome.wustl.edu	36	4	106416718	106416718	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	4	106416718	106416718	C	T	SNP	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	missense	c.2008	p.H670Y	1.000	NULL	NULL	-	no_start_codon	119	2	1.65	274	197	41.83	32	33	50.77
PCDHGA2	0	genome.wustl.edu	36	5	140699526	140699526	+	Silent	SNP	C	C	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	5	140699526	140699526	C	T	SNP	PCDHGA2	NM_018915.2	human	genbank	54_36p	+1	reviewed	silent	c.804	p.D268	0.635	HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like	-	no_errors	247	2	0.80	171	137	44.48	NA	NA	NA
KIAA0240	0	genome.wustl.edu	36	6	42940470	42940470	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	6	42940470	42940470	A	G	SNP	KIAA0240	NM_015349.1	human	genbank	54_36p	+1	validated	missense	c.2548	p.S850G	0.002	NULL	NULL	-	no_errors	234	6	2.50	184	181	49.59	20	16	44.44
LOC100130301	0	genome.wustl.edu	36	8	74316291	74316291	+	Silent	SNP	G	G	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	8	74316291	74316291	G	T	SNP	LOC100130301	XM_001721302.1	human	genbank	54_36p	-1	model	silent	c.441	p.T147	0.000	NULL	NULL	-	no_errors	93	6	6.06	125	102	44.93	NA	NA	NA
ADAMTSL1	0	genome.wustl.edu	36	9	18629381	18629381	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	9	18629381	18629381	G	T	SNP	ADAMTSL1	NM_001040272.4	human	genbank	54_36p	+1	validated	missense	c.806	p.G269V	1.000	NULL	HMMPfam_TSP_1,HMMSmart_SM00209,superfamily_TSP-1 type 1 repeat,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_PLAC,HMMPfam_I-set,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	167	8	4.57	278	256	47.85	NA	NA	NA
FAM171A1	0	genome.wustl.edu	36	10	15330670	15330670	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	10	15330670	15330670	G	A	SNP	FAM171A1	NM_001010924.1	human	genbank	54_36p	-1	validated	missense	c.728	p.A243V	0.765	HMMPfam_UPF0560	HMMPfam_UPF0560	-	no_errors	246	0	0.00	267	212	44.26	3	7	70.00
ITGA8	0	genome.wustl.edu	36	10	15698530	15698530	+	Silent	SNP	G	G	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	10	15698530	15698530	G	A	SNP	ITGA8	NM_003638.1	human	genbank	54_36p	-1	provisional	silent	c.1434	p.V478	0.954	HMMSmart_Int_alpha,superfamily_SSF69318	HMMPfam_Integrin_alpha,HMMPfam_FG-GAP,HMMSmart_Int_alpha,HMMPfam_Integrin_alpha2,PatternScan_INTEGRIN_ALPHA,superfamily_SSF69179,superfamily_SSF69318	-	no_errors	270	3	1.10	258	219	45.82	6	0	0.00
MKX	0	genome.wustl.edu	36	10	28063581	28063581	+	Silent	SNP	G	G	C			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	10	28063581	28063581	G	C	SNP	MKX	NM_173576.2	human	genbank	54_36p	-1	validated	silent	c.648	p.P216	0.635	NULL	HMMPfam_Homeobox,HMMSmart_HOX,superfamily_Homeodomain_like,PatternScan_HOMEOBOX_1	-	no_errors	257	5	1.91	131	137	50.93	NA	NA	NA
LOC100131699	0	genome.wustl.edu	36	10	86310725	86310725	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	10	86310725	86310725	G	C	SNP	LOC100131699	XM_001723921.1	human	genbank	54_36p	-1	model	missense	c.176	p.S59W	1.000	NULL	NULL	-	no_errors	107	4	3.60	135	109	44.67	330	1	0.30
OR5M5P	0	genome.wustl.edu	36	11	56051119	56051119	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	11	56051119	56051119	C	A	SNP	OR5M5P	ENST00000341231	human	ensembl	54_36p	-1	known	missense	c.196	p.A66S	0.001	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	282	2	0.70	223	181	44.80	NA	NA	NA
GDPD5	0	genome.wustl.edu	36	11	74824213	74824213	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	11	74824213	74824213	C	T	SNP	GDPD5	NM_030792.6	human	genbank	54_36p	-1	validated	missense	c.1805	p.R602Q	0.235	NULL	HMMPfam_GDPD,superfamily_PLC-like phosphodiesterases	-	no_errors	474	13	2.67	90	74	45.12	14	8	36.36
NALCN	0	genome.wustl.edu	36	13	100845643	100845643	+	Silent	SNP	G	G	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	13	100845643	100845643	G	A	SNP	NALCN	NM_052867.2	human	genbank	54_36p	-1	validated	silent	c.183	p.F61	1.000	superfamily_Voltage-gated potassium channels	HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels	-	no_errors	131	4	2.96	228	186	44.93	NA	NA	NA
ZNF213	0	genome.wustl.edu	36	16	3128460	3128460	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	16	3128460	3128460	G	A	SNP	ZNF213	NM_004220.1	human	genbank	54_36p	+1	validated	missense	c.440	p.R147Q	0.001	NULL	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_SCAN,HMMSmart_SM00431,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	217	0	0.00	171	160	47.76	4	4	50.00
ZNF616	0	genome.wustl.edu	36	19	57310035	57310035	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	19	57310035	57310035	G	T	SNP	ZNF616	NM_178523.3	human	genbank	54_36p	-1	validated	missense	c.2194	p.L732I	0.066	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	234	3	1.27	116	109	48.44	4	2	33.33
U2AF1	0	genome.wustl.edu	36	21	43397525	43397525	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	21	43397525	43397525	G	A	SNP	U2AF1	NM_001025203.1	human	genbank	54_36p	-1	reviewed	missense	c.101	p.S34F	1.000	HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1	HMMPfam_RRM_1,HMMSmart_RRM,HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1,superfamily_SSF54928	-	no_errors	220	7	3.08	83	61	42.36	71	77	51.68
TET2	0	genome.wustl.edu	36	4	106410231	106410232	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-AB-2996-03A-01D-0739-09	TCGA-AB-2996-11A-01D-0739-09	AG	AG	AG	-	AG	AG	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	625950a0-f786-4158-90b7-89cb96e4a23b	2b2ba0f5-7ab3-4ae0-9828-097cc0e89a15	4	106410231	106410232	AG	-	DEL	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_del	c.466_467	p.R156fs	1.000:1.000	NULL	NULL	-	no_start_codon	0	7	3.95	0	189	35.33	0	0	0.00