Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU DNMT3A 0 genome.wustl.edu 36 2 25310746 25310746 + Missense_Mutation SNP C C T TCGA-AB-2975-03A-01D-0739-09 TCGA-AB-2975-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 46b127f4-a3de-486c-8b90-d300ee13b182 07925c7f-550a-4728-908a-1ed34112da56 2 25310746 25310746 C T SNP DNMT3A NM_022552.3 human genbank 54_36p -1 reviewed missense c.2645 p.R882H 1.000 superfamily_S-adenosyl-L-methionine-dependent methyltransferases HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT - no_errors 28 16 36.36 10 21 65.62 25 28 52.83 RAD21 0 genome.wustl.edu 36 8 117938116 117938116 + Nonsense_Mutation SNP A A T TCGA-AB-2975-03A-01D-0739-09 TCGA-AB-2975-11A-01D-0739-09 A A A T A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 46b127f4-a3de-486c-8b90-d300ee13b182 07925c7f-550a-4728-908a-1ed34112da56 8 117938116 117938116 A T SNP RAD21 NM_006265.2 human genbank 54_36p -1 reviewed nonsense c.764 p.L255* 1.000 NULL HMMPfam_Rad21_Rec8,HMMPfam_Rad21_Rec8_N - no_errors 24 4 14.29 12 10 45.45 27 9 25.00