Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
ENSG00000169164	0	genome.wustl.edu	36	X	55700094	55700094	+	Silent	SNP	G	G	A			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	X	55700094	55700094	G	A	SNP	ENSG00000169164	ENST00000347911	human	ensembl	54_36p	-1	known	silent	c.28	p.L10	0.000	HMMPfam_GAGE	HMMPfam_GAGE	-	no_start_codon:no_stop_codon	498	59	10.57	404	355	46.77	NA	NA	NA
ACVR2B	0	genome.wustl.edu	36	3	38494675	38494675	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	3	38494675	38494675	C	T	SNP	ACVR2B	NM_001106.3	human	genbank	54_36p	+1	reviewed	missense	c.410	p.T137M	1.000	NULL	HMMPfam_Activin_recp,HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase,superfamily_Snake toxin-like	-	no_errors	331	62	15.78	240	183	43.26	NA	NA	NA
COL19A1	0	genome.wustl.edu	36	6	70909420	70909420	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	6	70909420	70909420	C	T	SNP	COL19A1	NM_001858.4	human	genbank	54_36p	+1	reviewed	missense	c.1613	p.P538L	1.000	HMMPfam_Collagen	HMMSmart_TSPN,HMMPfam_Collagen,superfamily_ConA_like_lec_gl	-	no_errors	542	68	11.1475409836066	376	253	40.2225755166932	4	0	0.00
RET	0	genome.wustl.edu	36	10	42920506	42920506	+	Silent	SNP	G	G	T			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	10	42920506	42920506	G	T	SNP	RET	NM_020975.4	human	genbank	54_36p	+1	reviewed	silent	c.726	p.V242	0.006	HMMPfam_Cadherin,HMMSmart_CA,superfamily_Cadherin	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,HMMPfam_Cadherin,HMMSmart_CA,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,superfamily_Cadherin,PatternScan_PROTEIN_KINASE_ATP	-	no_errors	262	53	16.8253968253968	174	132	43.1372549019608	1	0	0.00
ACTA2	0	genome.wustl.edu	36	10	90685089	90685089	+	Silent	SNP	C	C	T			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	10	90685089	90685089	C	T	SNP	ACTA2	NM_001613.1	human	genbank	54_36p	-1	reviewed	silent	c.1005	p.P335	1.000	HMMPfam_Actin,HMMSmart_SM00268,superfamily_Actin-like ATPase domain	HMMPfam_Actin,HMMSmart_SM00268,PatternScan_ACTINS_ACT_LIKE,PatternScan_ACTINS_1,PatternScan_ACTINS_2,superfamily_Actin-like ATPase domain	-	no_errors	486	0	0	496	1	0.201207243460765	23	0	0.00
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	367	49	11.78	136	18	11.69	82	54	39.42
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2973-03A-01D-0739-09	TCGA-AB-2973-11A-01D-0739-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	74dfde23-debb-4c0c-80cb-e06928350b5d	cf1f73e2-147b-42f5-8797-004eb789f776	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	166	27	13.9896373056995	129	67	34.1836734693878	NA	NA	NA