Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	1018	175	14.67	459	387	45.64	6	16	72.73
IDH1	0	genome.wustl.edu	36	2	208821357	208821357	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	2	208821357	208821357	C	T	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.395	p.R132H	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	811	129	13.71	865	412	32.24	142	90	38.63
FOXP1	0	genome.wustl.edu	36	3	71109483	71109483	+	Splice_Site	SNP	C	C	G			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	3	71109483	71109483	C	G	SNP	FOXP1	NM_032682.1	human	genbank	54_36p	-1	reviewed	splice_site	c.1428+1	e11+1	1.000	-	-	-	no_errors	671	30	4.27	973	157	13.88	20	0	0.00
SOHLH1	0	genome.wustl.edu	36	9	137726092	137726092	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	9	137726092	137726092	G	A	SNP	SOHLH1	NM_001101677.2	human	genbank	54_36p	-1	validated	missense	c.908	p.T303M	0.000	NULL	HMMPfam_HLH,HMMSmart_SM00353,superfamily_HLH helix-loop-helix DNA-binding domain	-	no_errors	451	7	1.52838427947598	91	5	5.20833333333333	0	0	0.00
KCNT1	0	genome.wustl.edu	36	9	137816463	137816463	+	Silent	SNP	G	G	A			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	9	137816463	137816463	G	A	SNP	KCNT1	NM_020822.1	human	genbank	54_36p	+1	provisional	silent	c.3063	p.T1021	0.991	NULL	HMMPfam_BK_channel_a,HMMPfam_Ion_trans_2,superfamily_NAD(P)-bd,superfamily_SSF81324	-	no_errors	55	0	0	224	15	6.27615062761506	0	0	0.00
LOC374443	0	genome.wustl.edu	36	12	9702101	9702101	+	RNA	SNP	A	A	G			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	12	9702101	9702101	A	G	SNP	LOC374443	NR_002814.1	human	genbank	54_36p	+1	provisional	rna	NULL	NULL	0.000	-	-	-	pseudogene	450	0	0	663	1	0.150602409638554	20	0	0.00
GLI1	0	genome.wustl.edu	36	12	56144791	56144791	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	12	56144791	56144791	C	A	SNP	GLI1	NM_005269.2	human	genbank	54_36p	+1	reviewed	missense	c.262	p.L88M	1.000	NULL	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	1538	337	17.95	656	591	47.39	1	0	0.00
FLT3	0	genome.wustl.edu	36	13	27490642	27490642	+	Missense_Mutation	SNP	C	C	G	rs121913488		TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	13	27490642	27490642	C	G	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2503	p.D835H	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	1256	159	11.22	866	429	33.08	222	95	29.78
ZNF276	0	genome.wustl.edu	36	16	88321243	88321243	+	Silent	SNP	C	C	T			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	16	88321243	88321243	C	T	SNP	ZNF276	NM_152287.1	human	genbank	54_36p	+1	validated	silent	c.837	p.D279	1.000	NULL	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMPfam_zf-AD,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	230	0	0	520	58	10.0346020761246	26	0	0.00
ELANE	0	genome.wustl.edu	36	19	806779	806779	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	19	806779	806779	G	T	SNP	ELA2	NM_001972.2	human	genbank	54_36p	+1	reviewed	missense	c.582	p.Q194H	0.937	HMMPfam_Trypsin,HMMSmart_Tryp_SPc,superfamily_Pept_Ser_Cys	HMMPfam_Trypsin,HMMSmart_Tryp_SPc,superfamily_Pept_Ser_Cys,PatternScan_TRYPSIN_HIS,PatternScan_TRYPSIN_SER	-	no_errors	363	91	20.0440528634361	15	23	60.5263157894737	88	54	37.76
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2969-03A-01D-0739-09	TCGA-AB-2969-11A-01D-0739-09	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	c2942501-aebc-4dc5-b31d-52d624f2f163	9f76ea23-0923-4b22-99ba-791ee8931003	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	169	34	16.7487684729064	87	70	44.5859872611465	NA	NA	NA