Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
MT-CO2	0	genome.wustl.edu	36	MT	7920	7920	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	MT	7920	7920	G	A	SNP	MT-CO2	ENST00000361739	human	ensembl	54_36p	+1	known	missense	c.334	p.D112N	NULL	HMMPfam_COX2,superfamily_Cupredoxins	PatternScan_COX2,HMMPfam_COX2,superfamily_Cupredoxins,HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region	-	no_errors	7626	378	4.72	3790	1965	33.92	NA	NA	NA
FAM47A	0	genome.wustl.edu	36	X	34060095	34060095	+	Silent	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	X	34060095	34060095	G	A	SNP	FAM47A	NM_203408.2	human	genbank	54_36p	-1	predicted	silent	c.222	p.D74	0.004	NULL	NULL	-	no_errors	146	17	10.43	40	35	46.05	NA	NA	NA
KLHL4	0	genome.wustl.edu	36	X	86659948	86659948	+	Silent	SNP	T	T	C			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	X	86659948	86659948	T	C	SNP	KLHL4	NM_057162.4	human	genbank	54_36p	+1	reviewed	silent	c.396	p.D132	0.948	NULL	HMMSmart_SM00225,HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain,superfamily_POZ domain,HMMPfam_BACK,HMMPfam_BTB	-	no_errors	112	9	7.44	18	25	58.14	NA	NA	NA
TAS1R1	0	genome.wustl.edu	36	1	6559262	6559262	+	Silent	SNP	A	A	G			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	1	6559262	6559262	A	G	SNP	TAS1R1	NM_138697.2	human	genbank	54_36p	+1	reviewed	silent	c.1461	p.G487	0.016	superfamily_Periplasmic binding protein-like I	HMMPfam_ANF_receptor,HMMPfam_NCD3G,HMMPfam_7tm_3,PatternScan_G_PROTEIN_RECEP_F3_2,PatternScan_G_PROTEIN_RECEP_F3_3,superfamily_Periplasmic binding protein-like I	-	no_errors	175	9	4.89	31	25	43.86	NA	NA	NA
CHRNB2	0	genome.wustl.edu	36	1	152810583	152810583	+	Silent	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	1	152810583	152810583	G	A	SNP	CHRNB2	NM_000748.2	human	genbank	54_36p	+1	reviewed	silent	c.660	p.T220	0.999	HMMPfam_Neur_chan_LBD,superfamily_Nicotinic receptor ligand binding domain-like	HMMPfam_Neur_chan_memb,superfamily_Neurotransmitter-gated ion-channel transmembrane pore,HMMPfam_Neur_chan_LBD,superfamily_Nicotinic receptor ligand binding domain-like,PatternScan_NEUROTR_ION_CHANNEL	-	no_errors	255	24	8.57	17	17	48.57	NA	NA	NA
NBAS	0	genome.wustl.edu	36	2	15333344	15333344	+	Silent	SNP	T	T	C			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	2	15333344	15333344	T	C	SNP	NBAS	NM_015909.2	human	genbank	54_36p	-1	validated	silent	c.5439	p.A1813	0.222	NULL	superfamily_WD40 repeat-like,HMMPfam_Sec39,PatternScan_RIBOSOMAL_S14	-	no_errors	242	17	6.56	67	44	39.29	28	17	37.78
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	233	21	8.24	50	34	40.00	34	40	53.33
COL7A1	0	genome.wustl.edu	36	3	48583702	48583702	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	3	48583702	48583702	G	A	SNP	COL7A1	NM_000094.3	human	genbank	54_36p	-1	reviewed	missense	c.7082	p.A2361V	1.000	HMMPfam_Collagen	HMMPfam_VWA,HMMSmart_SM00327,HMMPfam_Kunitz_BPTI,PatternScan_BPTI_KUNITZ_1,superfamily_BPTI-like,HMMPfam_fn3,HMMSmart_SM00060,HMMPfam_Collagen,superfamily_Fibronectin type III,superfamily_vWA-like	-	no_errors	276	19	6.44	46	28	37.84	NA	NA	NA
GATA2	0	genome.wustl.edu	36	3	129685499	129685499	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	3	129685499	129685499	G	T	SNP	GATA2	NM_032638.1	human	genbank	54_36p	-1	reviewed	missense	c.911	p.P304H	1.000	HMMPfam_GATA,HMMSmart_ZnF_GATA,PatternScan_GATA_ZN_FINGER_1,superfamily_SSF57716	HMMPfam_GATA,HMMSmart_ZnF_GATA,PatternScan_GATA_ZN_FINGER_1,superfamily_SSF57716	-	no_errors	82	3	3.53	12	7	36.84	6	12	66.67
RPS3A	0	genome.wustl.edu	36	4	152243488	152243488	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	4	152243488	152243488	C	T	SNP	RPS3A	NM_001006.3	human	genbank	54_36p	+1	reviewed	missense	c.370	p.H124Y	1.000	HMMPfam_Ribosomal_S3Ae	HMMPfam_Ribosomal_S3Ae,PatternScan_RIBOSOMAL_S3AE	-	no_errors	405	32	7.32	83	60	41.96	173	174	50.00
PCDHA1	0	genome.wustl.edu	36	5	140147758	140147758	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	5	140147758	140147758	G	A	SNP	PCDHA1	NM_018900.2	human	genbank	54_36p	+1	reviewed	missense	c.1699	p.A567T	0.018	superfamily_Cadherin-like	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like	-	no_errors	128	13	9.22	16	10	37.04	NA	NA	NA
PCDHB18	0	genome.wustl.edu	36	5	140595772	140595772	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	5	140595772	140595772	T	C	SNP	PCDHB18	ENST00000274705	human	ensembl	54_36p	+1	known	missense	c.1303	p.Y435H	0.998	HMMPfam_Cadherin,HMMSmart_CA,superfamily_Cadherin	HMMPfam_Cadherin,HMMSmart_CA,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin	-	no_errors	83	6	6.74	9	7	43.75	NA	NA	NA
PRPF4B	0	genome.wustl.edu	36	6	4002321	4002321	+	Silent	SNP	C	C	G			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	6	4002321	4002321	C	G	SNP	PRPF4B	NM_003913.4	human	genbank	54_36p	+1	reviewed	silent	c.2634	p.T878	0.859	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase	HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase	-	no_errors	164	15	8.38	42	35	45.45	38	45	53.57
LOC100129218	0	genome.wustl.edu	36	12	51171752	51171752	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	12	51171752	51171752	T	C	SNP	LOC100129218	XM_001718439.1	human	genbank	54_36p	+1	model	missense	c.997	p.F333L	1.000	NULL	NULL	-	no_errors	217	19	8.05	21	26	55.32	NA	NA	NA
MYH6	0	genome.wustl.edu	36	14	22944694	22944694	+	Nonsense_Mutation	SNP	G	G	C			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	14	22944694	22944694	G	C	SNP	MYH6	NM_002471.2	human	genbank	54_36p	-1	validated	nonsense	c.327	p.Y109*	1.000	HMMPfam_Myosin_head,HMMSmart_SM00242,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_Myosin_head,HMMSmart_SM00242,HMMPfam_Myosin_tail_1,HMMPfam_Myosin_N,superfamily_Prefoldin,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	668	52	7.21	71	67	48.20	NA	NA	NA
ENSG00000103832	0	genome.wustl.edu	36	15	28880384	28880384	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	15	28880384	28880384	G	T	SNP	ENSG00000103832	ENST00000220188	human	ensembl	54_36p	+1	known	missense	c.790	p.A264S	0.951	NULL	NULL	-	no_stop_codon	368	27	6.84	33	33	50.00	2	0	0.00
PLA2G4D	0	genome.wustl.edu	36	15	40160574	40160574	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	15	40160574	40160574	G	A	SNP	PLA2G4D	NM_178034.3	human	genbank	54_36p	-1	validated	missense	c.1007	p.T336I	0.864	HMMPfam_PLA2_B,HMMSmart_SM00022,superfamily_FabD/lysophospholipase-like	HMMPfam_C2,HMMSmart_SM00239,HMMPfam_PLA2_B,HMMSmart_SM00022,superfamily_C2 domain (Calcium/lipid-binding domain CaLB),superfamily_FabD/lysophospholipase-like	-	no_errors	170	7	3.95	21	17	44.74	NA	NA	NA
CCL16	0	genome.wustl.edu	36	17	31332517	31332517	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	17	31332517	31332517	G	A	SNP	CCL16	NM_004590.2	human	genbank	54_36p	-1	reviewed	missense	c.53	p.T18I	0.001	NULL	PatternScan_SMALL_CYTOKINES_CC,HMMPfam_IL8,HMMSmart_SCY,superfamily_Chemokine_IL8	-	no_errors	931	89	8.72	95	95	49.48	NA	NA	NA
DNAJC7	0	genome.wustl.edu	36	17	37387413	37387413	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	17	37387413	37387413	C	T	SNP	DNAJC7	NM_003315.1	human	genbank	54_36p	-1	provisional	missense	c.1340	p.G447D	1.000	superfamily_Chaperone J-domain	HMMPfam_TPR_1,HMMPfam_DnaJ,HMMSmart_SM00271,superfamily_Chaperone J-domain,HMMSmart_SM00028,superfamily_TPR-like	-	no_errors	340	16	4.48	50	29	36.25	41	23	35.94
ZNF254	0	genome.wustl.edu	36	19	24080696	24080696	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	19	24080696	24080696	C	G	SNP	ZNF254	NM_203282.2	human	genbank	54_36p	+1	validated	missense	c.145	p.L49V	0.994	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352)	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	108	4	3.57	30	18	37.50	10	6	35.29
CEBPA	0	genome.wustl.edu	36	19	38484244	38484245	+	In_Frame_Ins	INS	-	-	GCT			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	-	-	-	GCT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	19	38484244	38484245	-	GCT	INS	CEBPA	NM_004364.3	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.917_916	p.306in_frame_insQ	1.000:1.000	HMMSmart_BRLZ,HMMPfam_bZIP_2	HMMSmart_BRLZ,PatternScan_BZIP_BASIC,HMMPfam_bZIP_2	-	no_errors	31	3	8.82	3	3	50.00	58	24	29.27
CEBPA	0	genome.wustl.edu	36	19	38485024	38485024	+	Frame_Shift_Del	DEL	G	G	-			TCGA-AB-2955-03A-01W-0733-08	TCGA-AB-2955-11A-01W-0732-08	G	G	G	-	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	4e3241c5-adeb-4a0e-8e27-147ee63f32fd	c11cf123-f8e8-4777-b45f-d3498d8d38fa	19	38485024	38485024	G	-	DEL	CEBPA	NM_004364.3	human	genbank	54_36p	-1	reviewed	frame_shift_del	c.137	p.P46fs	1.000	NULL	HMMSmart_BRLZ,PatternScan_BZIP_BASIC,HMMPfam_bZIP_2	-	no_errors	0	0	0.00	0	0	0.00	14	9	37.50