Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
NRAS	0	genome.wustl.edu	36	1	115060267	115060267	+	Missense_Mutation	SNP	C	C	T	rs121434596		TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	1	115060267	115060267	C	T	SNP	NRAS	NM_002524.3	human	genbank	54_36p	-1	reviewed	missense	c.38	p.G13D	1.000	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	99	8	7.41	68	35	33.98	27	7	20.59
XIRP1	0	genome.wustl.edu	36	3	39203923	39203923	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	3	39203923	39203923	C	T	SNP	XIRP1	NM_194293.2	human	genbank	54_36p	-1	provisional	missense	c.2018	p.R673H	0.000	NULL	HMMPfam_Xin	-	no_errors	53	3	5.36	21	7	25.00	NA	NA	NA
LARS	0	genome.wustl.edu	36	5	145524130	145524130	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	5	145524130	145524130	G	C	SNP	LARS	NM_020117.9	human	genbank	54_36p	-1	reviewed	missense	c.530	p.A177G	1.000	superfamily_Nucleotidylyl transferase	PatternScan_AA_TRNA_LIGASE_I,superfamily_ValRS/IleRS/LeuRS editing domain,superfamily_Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases,HMMPfam_Anticodon_1,HMMPfam_tRNA-synt_1g,superfamily_Nucleotidylyl transferase	-	no_errors	92	8	8.00	67	45	40.18	21	23	52.27
NELL1	0	genome.wustl.edu	36	11	20915949	20915949	+	Silent	SNP	C	C	A			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	11	20915949	20915949	C	A	SNP	NELL1	NM_006157.3	human	genbank	54_36p	+1	reviewed	silent	c.1039	p.R347	0.995	HMMSmart_SM00214	PatternScan_ASX_HYDROXYL,HMMPfam_VWC,HMMSmart_SM00214,PatternScan_VWFC_1,HMMSmart_SM00282,HMMSmart_SM00179,HMMSmart_SM00210,HMMSmart_SM00181,HMMSmart_SM00215,superfamily_Concanavalin A-like lectins/glucanases,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,superfamily_EGF/Laminin	-	no_errors	220	11	4.76	201	60	22.99	NA	NA	NA
DSG2	0	genome.wustl.edu	36	18	27354841	27354841	+	Silent	SNP	T	T	G			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	18	27354841	27354841	T	G	SNP	DSG2	NM_001943.3	human	genbank	54_36p	+1	reviewed	silent	c.294	p.P98	0.573	HMMPfam_Cadherin,HMMSmart_CA,superfamily_Cadherin	HMMPfam_Cadherin,HMMSmart_CA,PatternScan_CADHERIN_1,superfamily_Cadherin	-	no_errors	68	2	2.78	33	32	49.23	NA	NA	NA
SETD2	0	genome.wustl.edu	36	3	47140156	47140157	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	-	-	-	C	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	3	47140156	47140157	-	C	INS	SETD2	ENST00000409792	human	ensembl	54_36p	-1	known	frame_shift_ins	c.974_973	p.E325fs	1.000:1.000	NULL	HMMPfam_WW,HMMSmart_SM00456,PatternScan_WW_DOMAIN_1,superfamily_WW domain,HMMPfam_SET,HMMSmart_SM00317,HMMSmart_SM00508,HMMSmart_SM00570,superfamily_Ferritin-like,HMMPfam_SRI_2,PatternScan_ADH_IRON_1,superfamily_SET domain	-	no_errors	0	0	0.00	0	0	0.00	18	16	47.06
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
UBE2R2	0	genome.wustl.edu	36	9	33907176	33907178	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-AB-2932-03A-01W-0745-08	TCGA-AB-2932-11A-01W-0745-08	GAG	GAG	GAG	-	GAG	GAG	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0e9732b4-5a84-4965-94d7-c73f5ad0c980	03f36e64-f07d-4c2d-b00f-d92b54742594	9	33907176	33907178	GAG	-	DEL	UBE2R2	NM_017811.3	human	genbank	54_36p	+1	reviewed	in_frame_del	c.658_660	p.E223in_frame_del	1.000:1.000:1.000	NULL	HMMPfam_UQ_con,HMMSmart_SM00212,PatternScan_UBIQUITIN_CONJUGAT_1,superfamily_UBC-like	-	no_errors	0	15	8.24	0	60	29.85	0	101	28.86