Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
ENSG00000211459	0	genome.wustl.edu	36	MT	913	913	+	RNA	SNP	T	T	C			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	MT	913	913	T	C	SNP	ENSG00000211459	ENST00000389680	human	ensembl	54_36p	+1	novel	rna	NULL	NULL	NULL	-	-	-	no_errors	1758	146	7.66	37	632	94.47	NA	NA	NA
HSPB7	0	genome.wustl.edu	36	1	16214717	16214717	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	1	16214717	16214717	C	T	SNP	HSPB7	NM_014424.4	human	genbank	54_36p	-1	validated	missense	c.458	p.R153H	0.906	HMMPfam_HSP20,superfamily_HSP20-like chaperones	HMMPfam_HSP20,superfamily_HSP20-like chaperones	-	no_errors	124	4	3.12	20	34	62.96	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25310747	25310747	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	2	25310747	25310747	G	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2644	p.R882C	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	106	4	3.64	23	20	46.51	41	50	54.95
ACTBL2	0	genome.wustl.edu	36	5	56813496	56813496	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	5	56813496	56813496	A	G	SNP	ACTBL2	NM_001017992.2	human	genbank	54_36p	-1	validated	missense	c.796	p.S266P	1.000	HMMPfam_Actin,HMMSmart_SM00268,superfamily_Actin-like ATPase domain	HMMPfam_Actin,HMMSmart_SM00268,PatternScan_ACTINS_ACT_LIKE,PatternScan_ACTINS_1,PatternScan_ACTINS_2,superfamily_Actin-like ATPase domain	-	no_errors	150	3	1.96	65	63	49.22	NA	NA	NA
SYNE1	0	genome.wustl.edu	36	6	152779761	152779761	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	6	152779761	152779761	C	T	SNP	SYNE1	NM_182961.2	human	genbank	54_36p	-1	reviewed	missense	c.5504	p.R1835H	0.024	superfamily_Spectrin repeat	PatternScan_ACTININ_1,PatternScan_ACTININ_2,HMMPfam_CH,HMMSmart_SM00033,HMMPfam_Spectrin,HMMPfam_KASH,superfamily_Calponin-homology domain CH-domain,HMMSmart_SM00150,superfamily_Spectrin repeat	-	no_errors	303	9	2.88	119	115	49.15	1	0	0.00
NRCAM	0	genome.wustl.edu	36	7	107618963	107618963	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	7	107618963	107618963	G	A	SNP	NRCAM	NM_001037132.1	human	genbank	54_36p	-1	reviewed	missense	c.1904	p.A635V	1.000	superfamily_Immunoglobulin	PatternScan_IG_MHC,HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,HMMPfam_I-set,HMMPfam_ig,superfamily_Immunoglobulin	-	no_errors	63	2	3.08	53	31	36.90	NA	NA	NA
GSTK1	0	genome.wustl.edu	36	7	142670742	142670742	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	7	142670742	142670742	C	T	SNP	GSTK1	NM_015917.1	human	genbank	54_36p	+1	reviewed	missense	c.14	p.P5L	0.419	superfamily_Thioredoxin-like	HMMPfam_DSBA,superfamily_Thioredoxin-like	-	no_errors	69	0	0.00	30	43	58.90	115	117	50.21
COL22A1	0	genome.wustl.edu	36	8	139766733	139766733	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	8	139766733	139766733	G	A	SNP	COL22A1	NM_152888.1	human	genbank	54_36p	-1	validated	missense	c.2867	p.A956V	0.108	HMMPfam_Collagen	HMMPfam_VWA,HMMSmart_SM00327,HMMSmart_SM00210,HMMPfam_Collagen,superfamily_Concanavalin A-like lectins/glucanases,superfamily_vWA-like	-	no_errors	48	0	0.00	29	4	12.12	NA	NA	NA
C3	0	genome.wustl.edu	36	19	6658203	6658203	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	19	6658203	6658203	C	T	SNP	C3	NM_000064.2	human	genbank	54_36p	-1	reviewed	missense	c.2129	p.R710Q	0.942	HMMPfam_ANATO,HMMSmart_SM00104,PatternScan_ANAPHYLATOXIN_1,superfamily_Anaphylotoxins (complement system)	HMMPfam_ANATO,HMMSmart_SM00104,PatternScan_ANAPHYLATOXIN_1,HMMPfam_A2M,HMMPfam_A2M_N,superfamily_Terpenoid cyclases/Protein prenyltransferases,superfamily_TIMP-like,HMMPfam_A2M_recep,superfamily_Alpha-macroglobulin receptor domain,HMMPfam_A2M_N_2,HMMPfam_A2M_comp,superfamily_Anaphylotoxins (complement system),HMMPfam_NTR,HMMSmart_SM00643,HMMPfam_Thiol-ester_cl,PatternScan_ALPHA_2_MACROGLOBULIN	-	no_errors	88	2	2.22	21	19	47.50	NA	NA	NA
NLRP11	0	genome.wustl.edu	36	19	61013186	61013186	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	19	61013186	61013186	T	G	SNP	NLRP11	NM_145007.3	human	genbank	54_36p	-1	validated	missense	c.602	p.E201A	0.072	HMMPfam_NACHT	PatternScan_CU2_MONOOXYGENASE_1,HMMSmart_SM00368,HMMPfam_PAAD_DAPIN,HMMPfam_NACHT,superfamily_DEATH domain,superfamily_RNI-like	-	no_errors	167	14	7.73	74	56	43.08	NA	NA	NA
KRTAP10-7	0	genome.wustl.edu	36	21	44845000	44845000	+	Silent	SNP	C	C	T			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	21	44845000	44845000	C	T	SNP	KRTAP10-7	NM_198689.2	human	genbank	54_36p	+1	validated	silent	c.51	p.S17	0.002	NULL	HMMPfam_Keratin_B2	-	no_errors	109	6	5.17	49	35	41.67	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506219	27506220	+	In_Frame_Ins	INS	-	-	AAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGCCCTG			TCGA-AB-2931-03A-01W-0745-08	TCGA-AB-2931-11A-01W-0745-08	-	-	-	AAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGCCCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	87ebd9e4-74d3-4314-85ea-86e6feacd628	af114bb0-997c-4288-ad46-547239566692	13	27506219	27506220	-	AAACTCTAAATTTTCTCTTGGAAACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGCCCTG	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1837_1836	p.612in_frame_insQGFYVDFREYEYDLKWEFPRENLEF	1.000:1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA