Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
KPRP	0	genome.wustl.edu	36	1	151000425	151000425	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	1	151000425	151000425	T	G	SNP	KPRP	NM_001025231.1	human	genbank	54_36p	+1	provisional	missense	c.1737	p.F579L	0.976	NULL	NULL	-	no_errors	47	0	0.00	76	40	34.48	NA	NA	NA
CFHR2	0	genome.wustl.edu	36	1	195185236	195185236	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	1	195185236	195185236	C	G	SNP	CFHR2	NM_005666.2	human	genbank	54_36p	+1	validated	missense	c.87	p.N29K	0.059	HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain	HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain	-	no_errors	107	3	2.73	97	46	32.17	0	0	0.00
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	2	25310746	25310746	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	41	1	2.38	64	47	42.34	14	20	58.82
BMP10	0	genome.wustl.edu	36	2	68946310	68946310	+	Missense_Mutation	SNP	A	A	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	2	68946310	68946310	A	T	SNP	BMP10	NM_014482.1	human	genbank	54_36p	-1	reviewed	missense	c.1232	p.F411Y	1.000	HMMPfam_TGF_beta,HMMSmart_TGFB,superfamily_SSF57501	HMMPfam_TGFb_propeptide,HMMPfam_TGF_beta,HMMSmart_TGFB,PatternScan_TGF_BETA_1,superfamily_SSF57501	-	no_errors	91	1	1.09	101	62	38.04	NA	NA	NA
TTN	0	genome.wustl.edu	36	2	179224470	179224470	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	2	179224470	179224470	C	T	SNP	TTN	ENST00000342992	human	ensembl	54_36p	-1	known	missense	c.2653	p.V885M	0.999	superfamily_DH-domain,HMMPfam_PPAK	superfamily_DH-domain,HMMSmart_IGc2,HMMSmart_IG,HMMPfam_fn3,HMMSmart_FN3,HMMPfam_PPAK,superfamily_FN_III-like,superfamily_ConA_like_lec_gl,superfamily_Man6php_recept,HMMPfam_I-set,HMMPfam_ig,PatternScan_FGGY_KINASES_1,superfamily_SSF48726	-	no_stop_codon	54	1	1.82	38	27	41.54	NA	NA	NA
GATA2	0	genome.wustl.edu	36	3	129682841	129682841	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	3	129682841	129682841	G	A	SNP	GATA2	NM_032638.1	human	genbank	54_36p	-1	reviewed	missense	c.1154	p.P385L	1.000	HMMSmart_ZnF_GATA,superfamily_SSF57716	HMMPfam_GATA,HMMSmart_ZnF_GATA,PatternScan_GATA_ZN_FINGER_1,superfamily_SSF57716	-	no_errors	54	0	0.00	54	41	43.16	11	93	89.42
SLC27A6	0	genome.wustl.edu	36	5	128379505	128379505	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	5	128379505	128379505	G	A	SNP	SLC27A6	NM_001017372.1	human	genbank	54_36p	+1	reviewed	missense	c.998	p.R333H	0.465	HMMPfam_AMP-binding,superfamily_SSF56801	HMMPfam_AMP-binding,PatternScan_AMP_BINDING,superfamily_SSF56801	-	no_errors	171	3	1.71	89	56	38.62	0	2	100.00
GABBR1	0	genome.wustl.edu	36	6	29689157	29689157	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	6	29689157	29689157	C	A	SNP	GABBR1	NM_001470.2	human	genbank	54_36p	-1	reviewed	missense	c.1408	p.A470S	1.000	HMMPfam_ANF_receptor,superfamily_Periplasmic binding protein-like I	HMMPfam_Sushi,HMMSmart_SM00032,HMMPfam_ANF_receptor,superfamily_Complement control module/SCR domain,HMMPfam_7tm_3,superfamily_Periplasmic binding protein-like I	-	no_errors	82	2	2.38	100	75	42.86	35	39	52.70
HECW1	0	genome.wustl.edu	36	7	43567983	43567983	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	7	43567983	43567983	C	T	SNP	HECW1	NM_015052.3	human	genbank	54_36p	+1	validated	missense	c.4754	p.S1585L	0.985	HMMPfam_HECT,HMMSmart_HECTc,superfamily_HECT	HMMPfam_C2,HMMSmart_C2,HMMPfam_HECT,HMMSmart_HECTc,superfamily_HECT,HMMPfam_WW,HMMSmart_WW,PatternScan_WW_DOMAIN_1,superfamily_WW_Rsp5_WWP,superfamily_C2_CaLB	-	no_errors	61	2	3.12	87	53	37.86	NA	NA	NA
GRM3	0	genome.wustl.edu	36	7	86253906	86253906	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	7	86253906	86253906	G	A	SNP	GRM3	NM_000840.2	human	genbank	54_36p	+1	reviewed	missense	c.862	p.A288T	0.999	HMMPfam_ANF_receptor,superfamily_Periplasmic binding protein-like I	HMMPfam_ANF_receptor,HMMPfam_NCD3G,HMMPfam_7tm_3,PatternScan_G_PROTEIN_RECEP_F3_1,PatternScan_G_PROTEIN_RECEP_F3_2,PatternScan_G_PROTEIN_RECEP_F3_3,superfamily_Periplasmic binding protein-like I	-	no_errors	7	0	0.00	13	19	59.38	NA	NA	NA
CSMD1	0	genome.wustl.edu	36	8	3068744	3068744	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	8	3068744	3068744	G	T	SNP	CSMD1	NM_033225.4	human	genbank	54_36p	-1	validated	missense	c.4402	p.L1468I	1.000	NULL	HMMPfam_Sushi,HMMSmart_SM00032,HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain,superfamily_Complement control module/SCR domain	-	pseudogene:no_stop_codon:bad_bp_length_for_coding_region	74	2	2.63	37	33	47.14	NA	NA	NA
CACNA1B	0	genome.wustl.edu	36	9	140135748	140135748	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	9	140135748	140135748	G	T	SNP	CACNA1B	NM_000718.2	human	genbank	54_36p	+1	validated	missense	c.6496	p.G2166C	1.000	NULL	HMMPfam_Ion_trans,HMMPfam_Ca_chan_IQ,superfamily_Voltage-gated potassium channels	-	no_errors	10	0	0.00	9	26	74.29	NA	NA	NA
RFC3	0	genome.wustl.edu	36	13	33302083	33302083	+	Missense_Mutation	SNP	A	A	C			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	13	33302083	33302083	A	C	SNP	RFC3	NM_002915.3	human	genbank	54_36p	+1	reviewed	missense	c.502	p.T168P	1.000	HMMSmart_SM00382,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00382,superfamily_DNA polymerase III clamp loader subunits C-terminal domain,HMMPfam_RFC-E_C,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	60	0	0.00	64	22	25.58	43	3	6.52
FAM154B	0	genome.wustl.edu	36	15	80361580	80361580	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	15	80361580	80361580	C	T	SNP	FAM154B	NM_001008226.1	human	genbank	54_36p	+1	predicted	missense	c.319	p.P107S	0.990	NULL	NULL	-	no_errors	58	1	1.67	57	46	44.66	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506255	27506256	+	In_Frame_Ins	INS	-	-	ATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATT			TCGA-AB-2925-03A-01W-0732-08	TCGA-AB-2925-11A-01W-0732-08	-	-	-	ATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	daa3c116-e029-483c-b07b-201a76a9519b	1ce4cb83-af5a-440a-a61a-b4b9d1fd81b6	13	27506255	27506256	-	ATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATT	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1801_1800	p.600in_frame_insNEYFYVDFREYEYD	1.000:0.998	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA