Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
LAS1L	0	genome.wustl.edu	36	X	64666340	64666340	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	X	64666340	64666340	C	T	SNP	LAS1L	NM_031206.3	human	genbank	54_36p	-1	provisional	missense	c.658	p.D220N	0.442	NULL	HMMPfam_Las1	-	no_errors	185	7	3.63	147	106	41.73	68	0	0.00
LPPR4	0	genome.wustl.edu	36	1	99544957	99544957	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	1	99544957	99544957	G	A	SNP	LPPR4	NM_014839.3	human	genbank	54_36p	+1	reviewed	missense	c.2095	p.G699R	1.000	NULL	HMMPfam_PAP2,HMMSmart_SM00014,superfamily_Acid phosphatase/Vanadium-dependent haloperoxidase	-	no_errors	82	6	6.82	159	54	25.12	NA	NA	NA
HIST3H3	0	genome.wustl.edu	36	1	226679386	226679386	+	Silent	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	1	226679386	226679386	C	T	SNP	HIST3H3	NM_003493.2	human	genbank	54_36p	-1	reviewed	silent	c.264	p.S88	0.986	HMMSmart_SM00428,HMMPfam_Histone,superfamily_Histone-fold	HMMSmart_SM00428,PatternScan_HISTONE_H3_1,HMMPfam_Histone,superfamily_Histone-fold	-	no_errors	43	0	0.00	84	25	22.94	1	0	0.00
SYNGAP1	0	genome.wustl.edu	36	6	33499266	33499266	+	Silent	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	6	33499266	33499266	C	T	SNP	SYNGAP1	NM_006772.2	human	genbank	54_36p	+1	validated	silent	c.57	p.Y19	1.000	HMMSmart_SM00233	HMMPfam_C2,HMMSmart_SM00239,HMMSmart_SM00233,HMMPfam_RasGAP,HMMSmart_SM00323,PatternScan_RAS_GTPASE_ACTIV_1,superfamily_GTPase activation domain GAP,superfamily_C2 domain (Calcium/lipid-binding domain CaLB),superfamily_PH domain-like	-	no_errors	67	8	10.67	73	57	43.85	1	0	0.00
GRB10	0	genome.wustl.edu	36	7	50641535	50641535	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	7	50641535	50641535	G	A	SNP	GRB10	NM_005311.2	human	genbank	54_36p	-1	reviewed	missense	c.1265	p.T422M	0.292	NULL	HMMPfam_RA,HMMSmart_SM00314,HMMPfam_SH2,HMMSmart_SM00252,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_BPS,superfamily_PH domain-like,superfamily_SH2 domain	-	no_errors	84	5	5.62	131	91	40.81	15	11	42.31
DLC1	0	genome.wustl.edu	36	8	13401792	13401792	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	8	13401792	13401792	G	A	SNP	DLC1	NM_182643.3	human	genbank	54_36p	-1	reviewed	missense	c.160	p.R54C	0.992	NULL	HMMPfam_RhoGAP,HMMSmart_SM00324,HMMPfam_START,HMMSmart_SM00234,superfamily_GTPase activation domain GAP,HMMPfam_SAM_2,superfamily_Bet v1-like	-	no_errors	100	2	1.96	144	109	42.91	NA	NA	NA
SORCS3	0	genome.wustl.edu	36	10	106792824	106792824	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	10	106792824	106792824	G	C	SNP	SORCS3	NM_014978.1	human	genbank	54_36p	+1	reviewed	missense	c.976	p.G326R	1.000	HMMSmart_VPS10,superfamily_SSF110296	HMMPfam_PKD,superfamily_PKD,HMMSmart_VPS10,superfamily_SSF110296	-	no_errors	102	4	3.77	118	111	48.26	NA	NA	NA
OR52D1	0	genome.wustl.edu	36	11	5467416	5467416	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	11	5467416	5467416	G	T	SNP	OR52D1	NM_001005163.1	human	genbank	54_36p	+1	provisional	nonsense	c.904	p.E302*	0.986	superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	98	1	1.01	220	65	22.57	NA	NA	NA
PTPRJ	0	genome.wustl.edu	36	11	48115300	48115300	+	Silent	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	11	48115300	48115300	C	T	SNP	PTPRJ	NM_002843.1	human	genbank	54_36p	+1	reviewed	silent	c.2043	p.D681	0.000	HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like	HMMPfam_Y_phosphatase,HMMSmart_PTPc,HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like,PatternScan_TYR_PHOSPHATASE_1,superfamily_SSF52799	-	no_errors	55	1	1.79	108	80	42.55	22	9	29.03
DRD2	0	genome.wustl.edu	36	11	112792868	112792868	+	Silent	SNP	G	G	A			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	11	112792868	112792868	G	A	SNP	DRD2	NM_000795.3	human	genbank	54_36p	-1	reviewed	silent	c.459	p.T153	0.950	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like	-	no_errors	150	8	5.06	188	73	27.76	NA	NA	NA
CBL	0	genome.wustl.edu	36	11	118654085	118654085	+	Splice_Site	SNP	G	G	C			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	11	118654085	118654085	G	C	SNP	CBL	NM_005188.2	human	genbank	54_36p	+1	reviewed	splice_site	c.1096-1	e8-1	1.000	-	-	-	no_errors	95	2	2.06	168	43	19.91	1	28	96.55
ZFC3H1	0	genome.wustl.edu	36	12	70316623	70316623	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	12	70316623	70316623	T	C	SNP	ZFC3H1	NM_144982.4	human	genbank	54_36p	-1	validated	missense	c.2014	p.I672V	0.832	NULL	HMMSmart_SM00386,HMMPfam_zf-C3H1,superfamily_Protein prenylyltransferase	-	no_errors	110	1	0.90	122	35	22.15	36	10	21.74
PTPN11	0	genome.wustl.edu	36	12	111372582	111372582	+	Missense_Mutation	SNP	C	C	T	rs121918454		TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	12	111372582	111372582	C	T	SNP	PTPN11	NM_002834.3	human	genbank	54_36p	+1	reviewed	missense	c.215	p.A72V	1.000	HMMPfam_SH2,HMMSmart_SM00252,superfamily_SH2 domain	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_SH2,HMMSmart_SM00252,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II,superfamily_SH2 domain	-	no_errors	37	3	7.50	103	37	26.24	31	5	13.89
ISLR	0	genome.wustl.edu	36	15	72254944	72254944	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	15	72254944	72254944	C	T	SNP	ISLR	NM_005545.3	human	genbank	54_36p	+1	validated	missense	c.692	p.A231V	0.299	superfamily_SSF48726,superfamily_SSF52058	HMMSmart_LRRNT,HMMPfam_LRRCT,HMMSmart_LRRCT,HMMPfam_LRR_1,HMMSmart_LRR_TYP,HMMSmart_IGc2,HMMPfam_I-set,superfamily_SSF48726,superfamily_SSF52058	-	no_errors	15	0	0.00	35	12	25.53	NA	NA	NA
KIF1C	0	genome.wustl.edu	36	17	4846516	4846516	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	17	4846516	4846516	C	T	SNP	KIF1C	NM_006612.4	human	genbank	54_36p	+1	provisional	nonsense	c.463	p.R155*	0.997	HMMPfam_Kinesin,HMMSmart_KISc,superfamily_SSF52540	HMMPfam_FHA,HMMSmart_FHA,HMMPfam_Kinesin,HMMSmart_KISc,superfamily_SMAD_FHA,PatternScan_KINESIN_MOTOR_DOMAIN1,superfamily_SSF52540	-	no_errors	118	9	7.09	78	59	42.75	4	1	20.00
SERPINB4	0	genome.wustl.edu	36	18	59456078	59456078	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	18	59456078	59456078	G	A	SNP	SERPINB4	NM_002974.2	human	genbank	54_36p	-1	validated	missense	c.1028	p.A343V	1.000	HMMPfam_Serpin,HMMSmart_SERPIN,superfamily_Prot_inh_serpin	HMMPfam_Serpin,HMMSmart_SERPIN,PatternScan_SERPIN,superfamily_Prot_inh_serpin	-	no_errors	84	2	2.33	139	37	20.90	NA	NA	NA
THOC5	0	genome.wustl.edu	36	22	28269470	28269470	+	Missense_Mutation	SNP	A	A	C			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	22	28269470	28269470	A	C	SNP	THOC5	NM_001002877.1	human	genbank	54_36p	-1	validated	missense	c.302	p.L101R	1.000	HMMPfam_FimP	HMMPfam_FimP	-	no_errors	231	19	7.57	200	150	42.74	20	20	50.00
STRN	0	genome.wustl.edu	36	2	36958647	36958649	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	AGA	AGA	AGA	-	AGA	AGA	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	2	36958647	36958649	AGA	-	DEL	STRN	NM_003162.2	human	genbank	54_36p	-1	validated	in_frame_del	c.1214_1212	p.S405in_frame_del	0.997:1.000:0.996	NULL	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_Striatin,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	0	0	0.00	0	0	0.00	0	0	0.00
CPXM2	0	genome.wustl.edu	36	10	125516574	125516574	+	Frame_Shift_Del	DEL	A	A	-			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	A	A	A	-	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	10	125516574	125516574	A	-	DEL	CPXM2	NM_198148.2	human	genbank	54_36p	-1	validated	frame_shift_del	c.1384	p.L462fs	0.596	HMMPfam_Peptidase_M14,HMMSmart_SM00631,superfamily_Zn-dependent exopeptidases	HMMPfam_F5_F8_type_C,HMMSmart_SM00231,PatternScan_FA58C_1,PatternScan_FA58C_2,HMMPfam_Peptidase_M14,HMMSmart_SM00631,PatternScan_CARBOXYPEPT_ZN_1,superfamily_Carboxypeptidase regulatory domain,superfamily_Galactose-binding domain-like,superfamily_Zn-dependent exopeptidases	-	no_errors	0	0	0.00	0	0	0.00	0	0	0.00
KANSL1	0	genome.wustl.edu	36	17	41604391	41604392	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2914-03A-01W-0732-08	TCGA-AB-2914-11A-01W-0732-08	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	2ae74530-0732-4031-bb63-3dbed2979f34	3c58db02-73a6-4c04-a358-121b95f364c2	17	41604391	41604392	-	G	INS	KIAA1267	NM_015443.2	human	genbank	54_36p	-1	validated	frame_shift_ins	c.896_895	p.R299fs	1.000:1.000	NULL	NULL	-	no_errors	113	0	0.00	176	47	21.08	77	11	12.50