Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DLGAP3	0	genome.wustl.edu	36	1	35142783	35142783	+	Silent	SNP	G	G	A			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	1	35142783	35142783	G	A	SNP	DLGAP3	NM_001080418.1	human	genbank	54_36p	-1	provisional	silent	c.789	p.S263	0.929	NULL	HMMPfam_GKAP	-	no_errors	1820	1	0.05	1242	884	41.58	NA	NA	NA
NES	0	genome.wustl.edu	36	1	154909179	154909179	+	Silent	SNP	G	G	A			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	1	154909179	154909179	G	A	SNP	NES	NM_006617.1	human	genbank	54_36p	-1	reviewed	silent	c.1425	p.S475	0.000	NULL	HMMPfam_Filament,PatternScan_IF	-	no_errors	178	2	1.11	170	145	46.03	NA	NA	NA
IL17RD	0	genome.wustl.edu	36	3	57106759	57106759	+	Nonsense_Mutation	SNP	G	G	C			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	3	57106759	57106759	G	C	SNP	IL17RD	NM_017563.3	human	genbank	54_36p	-1	validated	nonsense	c.1916	p.S639*	0.998	NULL	HMMPfam_SEFIR	-	no_errors	452	0	0.00	354	242	40.60	NA	NA	NA
PTPRG	0	genome.wustl.edu	36	3	61709633	61709633	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	3	61709633	61709633	C	G	SNP	PTPRG	NM_002841.3	human	genbank	54_36p	+1	reviewed	missense	c.127	p.H43D	1.000	NULL	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_Carb_anhydrase,superfamily_Carbonic anhydrase,HMMSmart_SM00404,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	941	0	0.00	464	352	43.03	NA	NA	NA
EPHB1	0	genome.wustl.edu	36	3	136355761	136355761	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	3	136355761	136355761	C	T	SNP	EPHB1	NM_004441.3	human	genbank	54_36p	+1	reviewed	nonsense	c.1375	p.Q459*	1.000	HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III	HMMPfam_Ephrin_lbd,HMMSmart_SM00615,HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,PatternScan_RECEPTOR_TYR_KIN_V_1,PatternScan_RECEPTOR_TYR_KIN_V_2,HMMPfam_SAM_1,HMMSmart_SM00454,HMMSmart_SM00220,HMMPfam_fn3,HMMSmart_SM00060,PatternScan_PROTEIN_KINASE_TYR,superfamily_Fibronectin type III,superfamily_Galactose-binding domain-like,superfamily_SAM/Pointed domain,superfamily_Protein kinase-like (PK-like),PatternScan_EGF_2,PatternScan_PROTEIN_KINASE_ATP	-	no_errors	1302	0	0.00	698	600	46.08	NA	NA	NA
MASP1	0	genome.wustl.edu	36	3	188420628	188420628	+	Silent	SNP	C	C	T			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	3	188420628	188420628	C	T	SNP	MASP1	NM_001879.1	human	genbank	54_36p	-1	reviewed	silent	c.2025	p.K675	0.930	HMMPfam_Trypsin,HMMSmart_SM00020,superfamily_Trypsin-like serine proteases	PatternScan_ASX_HYDROXYL,HMMPfam_Sushi,HMMSmart_SM00032,HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain,HMMPfam_Trypsin,HMMSmart_SM00020,HMMSmart_SM00179,superfamily_Trypsin-like serine proteases,PatternScan_EGF_2,superfamily_Complement control module/SCR domain,PatternScan_EGF_CA,PatternScan_TRYPSIN_HIS,PatternScan_TRYPSIN_SER,superfamily_EGF/Laminin	-	no_errors	1566	0	0.00	993	770	43.68	NA	NA	NA
LOC100133292	0	genome.wustl.edu	36	5	2645059	2645059	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	5	2645059	2645059	G	C	SNP	LOC100133292	XM_001715713.1	human	genbank	54_36p	-1	model	missense	c.227	p.T76R	0.065	NULL	NULL	-	no_errors	1188	0	0.00	517	374	41.93	NA	NA	NA
COL9A1	0	genome.wustl.edu	36	6	71041165	71041165	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	6	71041165	71041165	G	A	SNP	COL9A1	NM_001851.4	human	genbank	54_36p	-1	reviewed	missense	c.1007	p.S336F	0.948	HMMPfam_Collagen	HMMSmart_TSPN,HMMPfam_Collagen,superfamily_ConA_like_lec_gl	-	no_errors	1091	0	0.00	622	321	34.04	NA	NA	NA
IKZF1	0	genome.wustl.edu	36	7	50411953	50411953	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	7	50411953	50411953	A	G	SNP	IKZF1	ENST00000331340	human	ensembl	54_36p	+1	known	missense	c.389	p.N130S	1.000	PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	533	0	0.00	346	235	40.38	NA	NA	NA
LONRF1	0	genome.wustl.edu	36	8	12627703	12627703	+	Silent	SNP	A	A	G			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	8	12627703	12627703	A	G	SNP	LONRF1	NM_152271.3	human	genbank	54_36p	-1	provisional	silent	c.2067	p.S689	0.951	HMMPfam_LON,HMMSmart_SM00464	HMMSmart_SM00184,HMMPfam_LON,HMMSmart_SM00464,PatternScan_ZF_RING_1,HMMPfam_zf-C3HC4,HMMSmart_SM00028,superfamily_TPR-like,superfamily_RING/U-box	-	no_errors	988	2	0.20	640	469	42.25	NA	NA	NA
CUBN	0	genome.wustl.edu	36	10	16910969	16910969	+	Silent	SNP	C	C	T			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	10	16910969	16910969	C	T	SNP	CUBN	NM_001081.3	human	genbank	54_36p	-1	reviewed	silent	c.10605	p.T3535	0.938	HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain	PatternScan_ASX_HYDROXYL,HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain,HMMSmart_SM00179,HMMPfam_EGF,HMMSmart_SM00181,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin	-	no_errors	1390	5	0.36	747	596	44.35	NA	NA	NA
AURKB	0	genome.wustl.edu	36	17	8050891	8050891	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	17	8050891	8050891	G	A	SNP	AURKB	NM_004217.2	human	genbank	54_36p	-1	validated	missense	c.439	p.R147W	0.999	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase	HMMSmart_SM00219,PatternScan_N6_MTASE,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase	-	no_errors	806	1	0.12	319	278	46.33	NA	NA	NA
ADAM11	0	genome.wustl.edu	36	17	40192768	40192768	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	17	40192768	40192768	C	T	SNP	ADAM11	NM_002390.4	human	genbank	54_36p	+1	reviewed	missense	c.214	p.R72C	1.000	HMMPfam_Pep_M12B_propep	"HMMPfam_Reprolysin,HMMPfam_Disintegrin,HMMSmart_SM00050,superfamily_Blood coagulation inhibitor (disintegrin),HMMPfam_Pep_M12B_propep,HMMPfam_ADAM_CR,HMMSmart_SM00608,PatternScan_EGF_1,HMMPfam_EGF_2,PatternScan_DISINTEGRIN_1,superfamily_Metalloproteases (""zincins"") catalytic domain,superfamily_EGF/Laminin"	-	no_errors	78	0	0.00	74	53	41.41	NA	NA	NA
CCDC57	0	genome.wustl.edu	36	17	77652999	77652999	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	17	77652999	77652999	G	A	SNP	CCDC57	NM_198082.2	human	genbank	54_36p	-1	validated	missense	c.2596	p.P866S	0.000	NULL	NULL	-	no_errors	154	0	0.00	109	84	43.30	NA	NA	NA
THEG	0	genome.wustl.edu	36	19	324949	324949	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	19	324949	324949	C	G	SNP	THEG	NM_016585.3	human	genbank	54_36p	-1	reviewed	missense	c.494	p.C165S	0.051	NULL	HMMSmart_SM00705	-	no_errors	373	0	0.00	166	99	37.36	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27506255	27506256	+	In_Frame_Ins	INS	-	-	ATCATATTCATATTCTCTGAA			TCGA-AB-2906-03A-01D-0739-09	TCGA-AB-2906-11A-01D-0739-09	-	-	-	ATCATATTCATATTCTCTGAA	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1ab4740e-e48f-4d5f-8b48-1b249e12b164	b5561c6c-eece-4ac3-969b-094285b5e3ff	13	27506255	27506256	-	ATCATATTCATATTCTCTGAA	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1801_1800	p.600in_frame_insFREYEYD	1.000:0.998	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA