Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
USP24	0	genome.wustl.edu	36	1	55361707	55361707	+	Splice_Site	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	1	55361707	55361707	C	T	SNP	USP24	NM_015306.1	human	genbank	54_36p	-1	validated	splice_site	c.3796+1	e33+1	1.000	-	-	-	no_errors	97	2	2.02	170	136	44.16	1	96	96.00
DNMT3A	0	genome.wustl.edu	36	2	25313307	25313307	+	Splice_Site	SNP	A	A	C			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	2	25313307	25313307	A	C	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	splice_site	c.2478+2	e20+2	0.998	-	-	-	no_errors	27	0	0.00	14	13	46.43	6	5	45.45
DNMT3A	0	genome.wustl.edu	36	2	25315536	25315536	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	2	25315536	25315536	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2375	p.R792H	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	26	0	0.00	26	19	42.22	20	46	69.70
EPAS1	0	genome.wustl.edu	36	2	46456394	46456394	+	Silent	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	2	46456394	46456394	C	T	SNP	EPAS1	NM_001430.3	human	genbank	54_36p	+1	validated	silent	c.948	p.Y316	0.901	HMMSmart_PAC,HMMPfam_PAS_3,superfamily_SSF55785	HMMSmart_PAS,HMMPfam_HLH,HMMSmart_HLH,HMMSmart_PAC,superfamily_HLH_basic,HMMPfam_PAS_3,HMMPfam_HIF-1a_CTAD,superfamily_SSF55785	-	no_errors	126	2	1.56	64	58	47.54	8	0	0.00
PTPRN	0	genome.wustl.edu	36	2	219875113	219875113	+	Silent	SNP	A	A	C			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	A	A	A	C	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	2	219875113	219875113	A	C	SNP	PTPRN	NM_002846.2	human	genbank	54_36p	-1	reviewed	silent	c.984	p.A328	0.007	NULL	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	98	0	0.00	127	90	41.10	NA	NA	NA
ATP2C1	0	genome.wustl.edu	36	3	132197626	132197626	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	3	132197626	132197626	G	A	SNP	ATP2C1	NM_001001486.1	human	genbank	54_36p	+1	reviewed	missense	c.2107	p.V703I	1.000	superfamily_Calcium ATPase transmembrane domain M	HMMPfam_Cation_ATPase_N,HMMPfam_Hydrolase,HMMPfam_Cation_ATPase_C,HMMPfam_E1-E2_ATPase,PatternScan_ATPASE_E1_E2,superfamily_HAD-like,superfamily_Calcium ATPase transduction domain A,superfamily_Metal cation-transporting ATPase ATP-binding domain N,superfamily_Calcium ATPase transmembrane domain M	-	no_errors	76	0	0.00	56	50	47.17	66	39	37.14
FAM193A	0	genome.wustl.edu	36	4	2668082	2668082	+	Silent	SNP	G	G	A			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	4	2668082	2668082	G	A	SNP	C4orf8	NM_003704.3	human	genbank	54_36p	+1	validated	silent	c.2598	p.T866	0.983	NULL	NULL	-	no_errors	91	0	0.00	89	68	43.31	26	11	29.73
CRISPLD1	0	genome.wustl.edu	36	8	76092224	76092224	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	8	76092224	76092224	G	A	SNP	CRISPLD1	NM_031461.4	human	genbank	54_36p	+1	validated	missense	c.1111	p.G371S	1.000	HMMPfam_LCCL,HMMSmart_SM00603,superfamily_LCCL domain	HMMSmart_SM00198,HMMPfam_LCCL,HMMSmart_SM00603,superfamily_LCCL domain,HMMPfam_SCP,superfamily_PR-1-like,PatternScan_CRISP_2	-	no_errors	64	0	0.00	38	63	62.38	7	9	56.25
PCDH15	0	genome.wustl.edu	36	10	55257274	55257274	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	10	55257274	55257274	C	T	SNP	PCDH15	NM_033056.1	human	genbank	54_36p	-1	reviewed	missense	c.4252	p.A1418T	0.977	NULL	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like	-	no_errors	62	0	0.00	22	22	50.00	NA	NA	NA
TET1	0	genome.wustl.edu	36	10	70075610	70075610	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	10	70075610	70075610	C	T	SNP	TET1	NM_030625.2	human	genbank	54_36p	+1	validated	missense	c.3118	p.P1040S	0.000	NULL	HMMPfam_zf-CXXC	-	no_errors	152	0	0.00	78	62	43.66	3	1	25.00
MYO16	0	genome.wustl.edu	36	13	108177890	108177890	+	Silent	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	13	108177890	108177890	C	T	SNP	MYO16	NM_015011.1	human	genbank	54_36p	+1	validated	silent	c.399	p.A133	1.000	HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat	HMMPfam_IQ,HMMPfam_Myosin_head,HMMSmart_SM00242,HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	284	0	0.00	84	67	43.79	NA	NA	NA
ACAN	0	genome.wustl.edu	36	15	87202088	87202088	+	Silent	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	15	87202088	87202088	C	T	SNP	ACAN	NM_013227.2	human	genbank	54_36p	+1	reviewed	silent	c.4926	p.S1642	0.969	NULL	HMMPfam_Sushi,HMMSmart_SM00032,HMMPfam_Xlink,HMMSmart_SM00445,PatternScan_LINK_1,HMMPfam_Lectin_C,HMMSmart_SM00034,PatternScan_IG_MHC,HMMSmart_SM00406,HMMSmart_SM00409,HMMPfam_EGF,HMMSmart_SM00181,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_V-set,superfamily_Complement control module/SCR domain,superfamily_C-type lectin-like,PatternScan_C_TYPE_LECTIN_1,superfamily_Immunoglobulin,superfamily_EGF/Laminin	-	no_errors	36	1	2.70	29	18	38.30	NA	NA	NA
IDH2	0	genome.wustl.edu	36	15	88432842	88432842	+	Missense_Mutation	SNP	C	C	T	rs121913503		TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	15	88432842	88432842	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.515	p.R172K	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	78	0	0.00	43	32	42.11	80	81	50.31
CUEDC1	0	genome.wustl.edu	36	17	53317592	53317592	+	Silent	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	17	53317592	53317592	C	T	SNP	CUEDC1	NM_017949.1	human	genbank	54_36p	-1	provisional	silent	c.333	p.P111	0.274	NULL	HMMPfam_CUE,HMMSmart_SM00546,superfamily_UBA-like	-	no_errors	18	0	0.00	32	17	34.69	7	3	30.00
MEGF8	0	genome.wustl.edu	36	19	47564893	47564893	+	Silent	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	19	47564893	47564893	C	T	SNP	MEGF8	NM_001410.2	human	genbank	54_36p	+1	validated	silent	c.6339	p.D2113	1.000	NULL	PatternScan_ASX_HYDROXYL,HMMPfam_CUB,HMMSmart_CUB,superfamily_CUB,HMMSmart_EGF_CA,HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,PatternScan_EGF_LAM_1,HMMPfam_PSI,HMMSmart_PSI,HMMSmart_EGF,HMMPfam_Kelch_1,superfamily_Gal_oxid_central,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,PatternScan_C_TYPE_LECTIN_1,superfamily_SSF57196	-	no_errors	84	0	0.00	15	14	48.28	12	6	33.33
SEL1L2	0	genome.wustl.edu	36	20	13806170	13806170	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	20	13806170	13806170	C	T	SNP	SEL1L2	NM_025229.1	human	genbank	54_36p	-1	validated	missense	c.1022	p.G341E	1.000	HMMPfam_Sel1,HMMSmart_SEL1,superfamily_SSF81901	HMMPfam_Sel1,HMMSmart_SEL1,superfamily_SSF81901	-	no_errors	143	0	0.00	81	79	49.38	NA	NA	NA
DOPEY2	0	genome.wustl.edu	36	21	36522005	36522005	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	21	36522005	36522005	C	A	SNP	DOPEY2	NM_005128.2	human	genbank	54_36p	+1	validated	missense	c.1625	p.P542H	1.000	NULL	HMMPfam_Dopey_N	-	no_errors	126	0	0.00	40	28	41.18	18	15	45.45
ASXL2	0	genome.wustl.edu	36	2	25820737	25820738	+	Frame_Shift_Ins	INS	-	-	CT			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	-	-	-	CT	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	2	25820737	25820738	-	CT	INS	ASXL2	NM_018263.4	human	genbank	54_36p	-1	validated	frame_shift_ins	c.1973_1972	p.A658fs	1.000:1.000	NULL	NULL	-	no_errors	319	0	0.00	68	39	36.45	13	4	23.53
MPI	0	genome.wustl.edu	36	15	72972172	72972174	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-AB-2898-03A-01W-0733-08	TCGA-AB-2898-11A-01W-0732-08	GAG	GAG	GAG	-	GAG	GAG	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	cebc6078-57bf-4866-a96d-a9e4fdaaf44d	e0e506a6-aeda-49ac-9ce5-46792b9b8c25	15	72972172	72972174	GAG	-	DEL	MPI	NM_002435.1	human	genbank	54_36p	+1	reviewed	in_frame_del	c.463_465	p.E156in_frame_del	0.983:0.998:1.000	HMMPfam_PMI_typeI,superfamily_RmlC-like cupins	HMMPfam_PMI_typeI,superfamily_RmlC-like cupins,PatternScan_PMI_I_1,PatternScan_PMI_I_2	-	no_errors	0	0	0.00	0	13	20.63	0	3	15.00