Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
RIPPLY1	0	genome.wustl.edu	36	X	106032037	106032037	+	Silent	SNP	G	G	A			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	X	106032037	106032037	G	A	SNP	RIPPLY1	NM_138382.1	human	genbank	54_36p	-1	provisional	silent	c.220	p.L74	0.000	NULL	NULL	-	no_errors	124	6	4.62	40	98	69.50	NA	NA	NA
EPHA10	0	genome.wustl.edu	36	1	37959089	37959089	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	1	37959089	37959089	T	C	SNP	EPHA10	NM_001099439.1	human	genbank	54_36p	-1	validated	missense	c.2161	p.I721V	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like)	HMMPfam_Ephrin_lbd,HMMSmart_SM00615,HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,PatternScan_RECEPTOR_TYR_KIN_V_1,PatternScan_RECEPTOR_TYR_KIN_V_2,HMMPfam_SAM_1,HMMSmart_SM00454,HMMSmart_SM00220,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,superfamily_Galactose-binding domain-like,superfamily_SAM/Pointed domain,superfamily_Protein kinase-like (PK-like),PatternScan_EGF_2	-	no_errors	164	3	1.79	61	43	41.35	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25316811	25316811	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	2	25316811	25316811	C	T	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2186	p.R729Q	1.000	HMMPfam_DNA_methylase,superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	77	2	2.53	34	32	48.48	19	15	44.12
DNMT3A	0	genome.wustl.edu	36	2	25320526	25320526	+	Splice_Site	SNP	A	A	G			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	2	25320526	25320526	A	G	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	splice_site	c.1851+2	e14+2	1.000	-	-	-	no_errors	55	3	5.17	44	24	34.78	0	7	100.00
BSN	0	genome.wustl.edu	36	3	49676911	49676911	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	3	49676911	49676911	A	G	SNP	BSN	NM_003458.3	human	genbank	54_36p	+1	validated	missense	c.11660	p.Q3887R	1.000	NULL	HMMPfam_zf-piccolo,superfamily_FYVE_PHD_ZnF	-	no_errors	52	2	3.70	43	19	30.16	NA	NA	NA
GABRB1	0	genome.wustl.edu	36	4	47100206	47100206	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	4	47100206	47100206	C	T	SNP	GABRB1	NM_000812.3	human	genbank	54_36p	+1	reviewed	missense	c.659	p.S220F	1.000	HMMPfam_Neur_chan_LBD,superfamily_Neur_chan_LBD	HMMPfam_Neur_chan_memb,superfamily_Neu_channel_TM,HMMPfam_Neur_chan_LBD,superfamily_Neur_chan_LBD,PatternScan_NEUROTR_ION_CHANNEL	-	no_errors	447	16	3.40	146	69	31.36	0	1	100.00
CUL9	0	genome.wustl.edu	36	6	43274427	43274427	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	6	43274427	43274427	G	A	SNP	CUL9	NM_015089.2	human	genbank	54_36p	+1	validated	missense	c.2906	p.R969H	0.201	superfamily_ARM repeat	"HMMPfam_Cullin,HMMPfam_IBR,HMMSmart_SM00647,HMMPfam_APC10,superfamily_Galactose-binding domain-like,superfamily_ARM repeat,PatternScan_CULLIN_1,superfamily_Cullin homology domain,PatternScan_ZF_RING_1,PatternScan_CYTOCHROME_P450,superfamily_""Winged helix"" DNA-binding domain,superfamily_RING/U-box"	-	no_errors	361	11	2.96	116	93	44.50	31	21	40.38
CCL21	0	genome.wustl.edu	36	9	34700059	34700059	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	9	34700059	34700059	G	A	SNP	CCL21	NM_002989.2	human	genbank	54_36p	-1	reviewed	missense	c.5	p.A2V	0.983	NULL	HMMPfam_IL8,HMMSmart_SM00199,superfamily_Interleukin 8-like chemokines	-	no_errors	293	9	2.96	231	148	38.44	NA	NA	NA
FANCC	0	genome.wustl.edu	36	9	97051267	97051267	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	9	97051267	97051267	T	C	SNP	FANCC	NM_000136.2	human	genbank	54_36p	-1	reviewed	missense	c.128	p.E43G	0.998	HMMPfam_Fanconi_C	HMMPfam_Fanconi_C	-	no_errors	263	6	2.21	167	93	35.63	9	4	30.77
AK8	0	genome.wustl.edu	36	9	134688504	134688504	+	Silent	SNP	C	C	T			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	9	134688504	134688504	C	T	SNP	C9orf98	NM_152572.2	human	genbank	54_36p	-1	validated	silent	c.798	p.P266	0.982	superfamily_P-loop containing nucleoside triphosphate hydrolases	"HMMPfam_ADK,superfamily_Microbial and mitochondrial ADK insert ""zinc finger"" domain,superfamily_P-loop containing nucleoside triphosphate hydrolases"	-	no_errors	189	6	3.00	144	64	30.48	NA	NA	NA
MAP6	0	genome.wustl.edu	36	11	74994526	74994526	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	11	74994526	74994526	T	A	SNP	MAP6	NM_033063.1	human	genbank	54_36p	-1	reviewed	missense	c.1291	p.N431Y	1.000	HMMPfam_STOP	HMMPfam_STOP	-	no_errors	382	13	3.27	106	70	39.77	NA	NA	NA
C11orf70	0	genome.wustl.edu	36	11	101459121	101459121	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	11	101459121	101459121	G	A	SNP	C11orf70	NM_032930.1	human	genbank	54_36p	+1	predicted	missense	c.671	p.G224D	1.000	NULL	NULL	-	no_errors	243	6	2.39	65	41	38.68	NA	NA	NA
ETV6	0	genome.wustl.edu	36	12	11930226	11930226	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	12	11930226	11930226	A	G	SNP	ETV6	NM_001987.4	human	genbank	54_36p	+1	reviewed	missense	c.1252	p.R418G	1.000	"HMMPfam_Ets,HMMSmart_SM00413,superfamily_""Winged helix"" DNA-binding domain"	"HMMPfam_Ets,HMMSmart_SM00413,PatternScan_ETS_DOMAIN_2,HMMPfam_SAM_PNT,HMMSmart_SM00251,superfamily_SAM/Pointed domain,superfamily_""Winged helix"" DNA-binding domain"	-	no_errors	255	16	5.84	55	67	54.47	2	40	95.24
CLPX	0	genome.wustl.edu	36	15	63243500	63243500	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	15	63243500	63243500	T	C	SNP	CLPX	NM_006660.3	human	genbank	54_36p	-1	provisional	missense	c.593	p.Y198C	1.000	superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00382,HMMPfam_AAA_2,HMMPfam_ClpB_D2-small,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	172	6	3.33	77	41	34.75	23	36	61.02
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	180	8	4.23	78	61	43.88	220	203	47.99
PDCD2L	0	genome.wustl.edu	36	19	39592210	39592210	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2891-03A-01W-0733-08	TCGA-AB-2891-11A-01W-0732-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	28b7dbc1-ed11-48c8-965f-460700b005d3	c23c8e94-494f-402f-a61e-c38bb20ec809	19	39592210	39592210	A	G	SNP	PDCD2L	NM_032346.1	human	genbank	54_36p	+1	provisional	missense	c.641	p.Y214C	0.998	HMMPfam_PDCD2_C	HMMPfam_PDCD2_C	-	no_errors	549	23	3.97	107	85	44.04	2	0	0.00