Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU TET2 0 genome.wustl.edu 36 4 106384227 106384227 + Nonsense_Mutation SNP C C T TCGA-AB-2879-03A-01W-0732-08 TCGA-AB-2879-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq f8e05d5a-f2b4-4023-b0d5-548df03a1921 d48634c4-b8d4-4fe7-b5a1-428c3682337f 4 106384227 106384227 C T SNP TET2 ENST00000265149 human ensembl 54_36p +1 known nonsense c.52 p.R18* 1.000 NULL NULL - no_start_codon 130 19 12.58 96 86 46.74 24 24 50.00 TRPM3 0 genome.wustl.edu 36 9 72408131 72408131 + Missense_Mutation SNP C C T TCGA-AB-2879-03A-01W-0732-08 TCGA-AB-2879-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq f8e05d5a-f2b4-4023-b0d5-548df03a1921 d48634c4-b8d4-4fe7-b5a1-428c3682337f 9 72408131 72408131 C T SNP TRPM3 NM_001007471.1 human genbank 54_36p -1 reviewed missense c.2707 p.E903K 1.000 NULL HMMPfam_Ion_trans - no_errors 228 23 9.09 219 162 41.86 NA NA NA TET2 0 genome.wustl.edu 36 4 106375370 106375370 + Frame_Shift_Del DEL C C - TCGA-AB-2879-03A-01W-0732-08 TCGA-AB-2879-11A-01W-0732-08 C C C - C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq f8e05d5a-f2b4-4023-b0d5-548df03a1921 d48634c4-b8d4-4fe7-b5a1-428c3682337f 4 106375370 106375370 C - DEL TET2 NM_017628.1 human genbank 54_36p +1 validated frame_shift_del c.822 p.N275fs 0.379 NULL NULL - no_errors 217 40 15.09 167 113 38.05 27 30 49.18 NPM1 0 genome.wustl.edu 36 5 170770152 170770153 + Frame_Shift_Ins INS - - TCTG TCGA-AB-2879-03A-01W-0732-08 TCGA-AB-2879-11A-01W-0732-08 - - - TCTG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq f8e05d5a-f2b4-4023-b0d5-548df03a1921 d48634c4-b8d4-4fe7-b5a1-428c3682337f 5 170770152 170770153 - TCTG INS NPM1 NM_002520.1 human genbank 54_36p +1 validated frame_shift_ins c.863_864 p.W288fs 1.000:1.000 NULL HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain - no_errors NA NA NA NA NA NA NA NA NA FLT3 0 genome.wustl.edu 36 13 27506250 27506251 + In_Frame_Ins INS - - TTGAGATCATATTCATATTCTCTGAAATCAACG TCGA-AB-2879-03A-01W-0732-08 TCGA-AB-2879-11A-01W-0732-08 - - - TTGAGATCATATTCATATTCTCTGAAATCAACG - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq f8e05d5a-f2b4-4023-b0d5-548df03a1921 d48634c4-b8d4-4fe7-b5a1-428c3682337f 13 27506250 27506251 - TTGAGATCATATTCATATTCTCTGAAATCAACG INS FLT3 NM_004119.2 human genbank 54_36p -1 reviewed in_frame_ins c.1806_1805 p.602in_frame_insNVDFREYEYDL 0.998:1.000 superfamily_Kinase_like HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726 - no_errors NA NA NA NA NA NA NA NA NA