Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU ETV3 0 genome.wustl.edu 36 1 155371935 155371935 + Missense_Mutation SNP C C T TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 1 155371935 155371935 C T SNP ETV3 NM_005240.1 human genbank 54_36p -1 validated missense c.236 p.R79K 1.000 HMMPfam_Ets,HMMSmart_ETS,superfamily_SSF46785 HMMPfam_Ets,HMMSmart_ETS,PatternScan_ETS_DOMAIN_1,PatternScan_ETS_DOMAIN_2,superfamily_SSF46785 - no_errors 317 14 4.23 177 128 41.16 6 6 50.00 GREM2 0 genome.wustl.edu 36 1 238723327 238723327 + Missense_Mutation SNP G G T TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 1 238723327 238723327 G T SNP GREM2 NM_022469.3 human genbank 54_36p -1 reviewed missense c.72 p.N24K 1.000 NULL HMMPfam_DAN,HMMSmart_CT - no_errors 47 1 2.08 66 40 37.38 NA NA NA OR6B2 0 genome.wustl.edu 36 2 240617625 240617625 + Missense_Mutation SNP C C A TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 2 240617625 240617625 C A SNP OR6B2 NM_001005853.1 human genbank 54_36p -1 provisional missense c.895 p.D299Y 0.046 superfamily_Family A G protein-coupled receptor-like HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like - no_errors 78 0 0.00 81 71 45.81 NA NA NA ARMC3 0 genome.wustl.edu 36 10 23359678 23359678 + Silent SNP C C A TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C A C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 10 23359678 23359678 C A SNP ARMC3 NM_173081.3 human genbank 54_36p +1 validated silent c.2193 p.T731 1.000 NULL HMMPfam_Arm,HMMSmart_SM00185,superfamily_ARM repeat - no_errors 332 7 2.05 168 142 45.08 NA NA NA WT1 0 genome.wustl.edu 36 11 32370142 32370142 + Missense_Mutation SNP G G A rs121907900 TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 11 32370142 32370142 G A SNP WT1 NM_024426.3 human genbank 54_36p -1 reviewed missense c.1384 p.R462W 1.000 HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers HMMPfam_WT1,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers - no_errors 142 1 0.69 124 46 26.90 16 7 30.43 CCDC60 0 genome.wustl.edu 36 12 118453114 118453114 + Missense_Mutation SNP G G A TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 12 118453114 118453114 G A SNP CCDC60 NM_178499.3 human genbank 54_36p +1 validated missense c.1414 p.A472T 0.954 NULL NULL - no_errors 161 3 1.83 123 112 46.86 NA NA NA SLITRK1 0 genome.wustl.edu 36 13 83352095 83352095 + Missense_Mutation SNP G G T TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 13 83352095 83352095 G T SNP SLITRK1 NM_052910.1 human genbank 54_36p -1 validated missense c.1549 p.Q517K 1.000 superfamily_SSF52058 HMMSmart_LRRNT,HMMSmart_LRRCT,HMMPfam_LRR_1,HMMSmart_LRR_TYP,superfamily_SSF52058 - no_errors 161 7 4.17 70 61 46.21 NA NA NA IDH2 0 genome.wustl.edu 36 15 88432938 88432938 + Missense_Mutation SNP C C T rs121913502 TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 15 88432938 88432938 C T SNP IDH2 NM_002168.2 human genbank 54_36p -1 reviewed missense c.419 p.R140Q 1.000 HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like - no_errors 116 6 4.92 91 79 46.20 137 106 43.62 MEFV 0 genome.wustl.edu 36 16 3239463 3239463 + Missense_Mutation SNP C C T TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 16 3239463 3239463 C T SNP MEFV NM_000243.2 human genbank 54_36p -1 reviewed missense c.1229 p.R410H 0.025 HMMPfam_zf-B_box,HMMSmart_SM00336,superfamily_B-box zinc-binding domain HMMPfam_zf-B_box,HMMSmart_SM00336,HMMPfam_SPRY,HMMPfam_PAAD_DAPIN,HMMSmart_SM00589,superfamily_DEATH domain,HMMSmart_SM00449,superfamily_B-box zinc-binding domain - no_errors 140 2 1.40 61 75 54.74 NA NA NA SMG1 0 genome.wustl.edu 36 16 18760441 18760441 + Missense_Mutation SNP A A G TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 A A A G A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 16 18760441 18760441 A G SNP SMG1 NM_015092.4 human genbank 54_36p -1 reviewed missense c.6643 p.F2215L 1.000 HMMPfam_PI3_PI4_kinase,HMMSmart_SM00146,superfamily_Protein kinase-like (PK-like) HMMPfam_HEAT,HMMPfam_PI3_PI4_kinase,HMMSmart_SM00146,HMMPfam_FATC,superfamily_Protein kinase-like (PK-like),superfamily_ARM repeat,PatternScan_PI3_4_KINASE_2 - no_errors 469 12 2.49 168 145 45.45 51 49 49.00 GPATCH8 0 genome.wustl.edu 36 17 39831216 39831216 + Missense_Mutation SNP G G A TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 17 39831216 39831216 G A SNP GPATCH8 NM_001002909.1 human genbank 54_36p -1 validated missense c.3755 p.T1252I 1.000 NULL HMMPfam_G-patch,HMMSmart_SM00443,PatternScan_ZINC_FINGER_C2H2_1 - no_errors 394 10 2.44 157 154 49.36 33 24 41.38 CEBPA 0 genome.wustl.edu 36 19 38484263 38484263 + Missense_Mutation SNP G G A TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 19 38484263 38484263 G A SNP CEBPA NM_004364.3 human genbank 54_36p -1 reviewed missense c.898 p.R300C 1.000 HMMSmart_BRLZ,HMMPfam_bZIP_2 HMMSmart_BRLZ,PatternScan_BZIP_BASIC,HMMPfam_bZIP_2 - no_errors 0 0 0.00 65 47 41.96 260 212 44.82 PDCD2L 0 genome.wustl.edu 36 19 39596586 39596586 + Missense_Mutation SNP T T C TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 19 39596586 39596586 T C SNP PDCD2L NM_032346.1 human genbank 54_36p +1 provisional missense c.791 p.I264T 1.000 HMMPfam_PDCD2_C HMMPfam_PDCD2_C - no_errors 206 6 2.82 86 71 44.94 3 3 50.00 FCGBP 0 genome.wustl.edu 36 19 45075959 45075959 + Missense_Mutation SNP C C G TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C G C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 19 45075959 45075959 C G SNP FCGBP NM_003890.2 human genbank 54_36p -1 validated missense c.9491 p.C3164S 1.000 superfamily_Cysrich_TIL,HMMPfam_TIL HMMSmart_VWC,HMMPfam_VWD,HMMSmart_VWD,superfamily_Cysrich_TIL,HMMPfam_TIL_assoc,HMMSmart_FOLN,HMMPfam_C8,HMMPfam_TIL - no_errors 375 3 0.79 193 45 18.83 NA NA NA AURKC 0 genome.wustl.edu 36 19 62435849 62435849 + Missense_Mutation SNP C C T TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 19 62435849 62435849 C T SNP AURKC NM_001015878.1 human genbank 54_36p +1 reviewed missense c.424 p.R142C 0.983 HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),PatternScan_PROTEIN_KINASE_ATP,HMMPfam_Pkinase - no_errors 250 1 0.40 156 27 14.67 1 0 0.00 LOC257039 0 genome.wustl.edu 36 3 145057398 145057398 + Frame_Shift_Del DEL T T - TCGA-AB-2874-03A-01W-0732-08 TCGA-AB-2874-11A-01W-0732-08 T T T - T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 0f1fb2e2-2463-4e1d-af0b-069bc0144e88 69a5771e-80a6-4c0e-af50-c10f51c985f6 3 145057398 145057398 T - DEL LOC257039 XM_172230.1 human genbank 54_36p -1 model frame_shift_del c.542 p.E181fs 1.000 HMMPfam_Ribosomal_S17e HMMPfam_Ribosomal_S17e - no_errors 110 0 0.00 70 70 47.95 0 0 0.00