Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
PLOD1	0	genome.wustl.edu	36	1	11947397	11947397	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	1	11947397	11947397	G	A	SNP	PLOD1	NM_000302.2	human	genbank	54_36p	+1	reviewed	missense	c.1438	p.D480N	0.997	NULL	PatternScan_LYS_HYDROXYLASE,HMMPfam_2OG-FeII_Oxy,HMMSmart_P4Hc	-	no_errors	26	0	0.00	8	5	38.46	40	31	43.66
MNDA	0	genome.wustl.edu	36	1	157082073	157082073	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	1	157082073	157082073	G	A	SNP	MNDA	NM_002432.1	human	genbank	54_36p	+1	reviewed	missense	c.643	p.V215M	0.003	HMMPfam_HIN	HMMPfam_PAAD_DAPIN,HMMPfam_HIN	-	no_errors	76	0	0.00	73	30	29.13	124	130	51.18
LOC644456	0	genome.wustl.edu	36	2	58541604	58541604	+	RNA	SNP	C	C	T			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	2	58541604	58541604	C	T	SNP	LOC644456	XR_039438.1	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.005	-	-	-	pseudogene	75	2	2.60	162	50	23.36	18	0	0.00
VN2R1P	0	genome.wustl.edu	36	3	157237331	157237331	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	3	157237331	157237331	G	A	SNP	CASRL1	ENST00000312652	human	ensembl	54_36p	+1	known	missense	c.1430	p.R477K	0.173	HMMPfam_7tm_3	HMMPfam_ANF_receptor,HMMPfam_NCD3G,HMMPfam_7tm_3,PatternScan_G_PROTEIN_RECEP_F3_1,PatternScan_G_PROTEIN_RECEP_F3_2,PatternScan_G_PROTEIN_RECEP_F3_3,superfamily_SSF53822	-	no_errors	27	0	0.00	77	29	27.36	NA	NA	NA
HS3ST1	0	genome.wustl.edu	36	4	11010116	11010116	+	Silent	SNP	C	C	T			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	4	11010116	11010116	C	T	SNP	HS3ST1	NM_005114.2	human	genbank	54_36p	-1	reviewed	silent	c.612	p.L204	0.999	HMMPfam_Sulfotransfer_1,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_Sulfotransfer_1,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	23	0	0.00	31	19	38.00	13	8	38.10
FRAS1	0	genome.wustl.edu	36	4	79407574	79407574	+	Silent	SNP	C	C	T			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	4	79407574	79407574	C	T	SNP	FRAS1	ENST00000380674	human	ensembl	54_36p	+1	known	silent	c.945	p.C315	1.000	HMMPfam_VWC,HMMSmart_SM00214,PatternScan_VWFC_1	HMMPfam_VWC,HMMSmart_SM00214,PatternScan_VWFC_1,HMMPfam_Calx-beta,HMMSmart_SM00237,HMMSmart_SM00181,HMMSmart_SM00261,HMMSmart_SM00215,superfamily_Growth factor receptor domain	-	no_errors	49	1	2.00	141	44	23.78	NA	NA	NA
DCHS2	0	genome.wustl.edu	36	4	155473290	155473290	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	4	155473290	155473290	T	A	SNP	DCHS2	NM_017639.1	human	genbank	54_36p	-1	validated	missense	c.2023	p.S675C	1.000	HMMSmart_SM00112,superfamily_Cadherin-like	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,superfamily_Cadherin-like	-	no_errors	29	0	0.00	50	35	41.18	NA	NA	NA
LOC392008	0	genome.wustl.edu	36	7	27275629	27275629	+	RNA	SNP	C	C	T			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	7	27275629	27275629	C	T	SNP	LOC392008	XR_017366.1	human	genbank	54_36p	-1	model	rna	NULL	NULL	1.000	-	-	-	no_errors	38	0	0.00	48	28	36.84	NA	NA	NA
CLIP2	0	genome.wustl.edu	36	7	73428914	73428914	+	Silent	SNP	C	C	T			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	7	73428914	73428914	C	T	SNP	CLIP2	NM_003388.4	human	genbank	54_36p	+1	reviewed	silent	c.2247	p.I749	0.992	NULL	HMMPfam_CAP_GLY,PatternScan_CAP_GLY_1,superfamily_Cap-Gly domain	-	no_errors	35	0	0.00	46	13	22.03	17	13	43.33
ENTPD1	0	genome.wustl.edu	36	10	97597217	97597217	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	10	97597217	97597217	G	A	SNP	ENTPD1	NM_001098175.1	human	genbank	54_36p	+1	validated	missense	c.859	p.D287N	0.005	HMMPfam_GDA1_CD39	HMMPfam_GDA1_CD39,PatternScan_GDA1_CD39_NTPASE	-	no_errors	36	0	0.00	71	17	19.10	20	8	28.57
NPAS4	0	genome.wustl.edu	36	11	65948991	65948991	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	11	65948991	65948991	A	G	SNP	NPAS4	NM_178864.3	human	genbank	54_36p	+1	validated	missense	c.2054	p.D685G	0.874	NULL	HMMSmart_PAS,HMMPfam_PAS_3,superfamily_SSF55785	-	no_errors	57	2	3.39	13	9	40.91	NA	NA	NA
MUC16	0	genome.wustl.edu	36	19	8921849	8921849	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	19	8921849	8921849	G	A	SNP	MUC16	NM_024690.2	human	genbank	54_36p	-1	validated	missense	c.26597	p.S8866L	0.000	NULL	HMMPfam_SEA,HMMSmart_SM00200,PatternScan_ATPASE_ALPHA_BETA,superfamily_SEA domain	-	no_errors	176	3	1.64	110	37	24.83	NA	NA	NA
RYR1	0	genome.wustl.edu	36	19	43679015	43679015	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	19	43679015	43679015	G	A	SNP	RYR1	NM_000540.2	human	genbank	54_36p	+1	reviewed	missense	c.6790	p.G2264S	1.000	HMMPfam_RYDR_ITPR	HMMPfam_RYDR_ITPR,HMMPfam_RyR,HMMPfam_MIR,superfamily_MIR domain (Pfam 02815),HMMPfam_SPRY,HMMPfam_Ion_trans,HMMPfam_RR_TM4-6,HMMPfam_RIH_assoc,HMMPfam_Ins145_P3_rec,HMMSmart_SM00472,HMMSmart_SM00449,superfamily_EF-hand	-	no_errors	18	0	0.00	10	6	37.50	NA	NA	NA
TP53	0	genome.wustl.edu	36	17	7520294	7520295	+	Frame_Shift_Ins	INS	-	-	CCATCCAG			TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	-	-	-	CCATCCAG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	17	7520294	7520295	-	CCATCCAG	INS	TP53	NM_000546.4	human	genbank	54_36p	-1	reviewed	frame_shift_ins	c.118_117	p.M39fs	0.000:0.000	NULL	PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53_tetramer,superfamily_p53 tetramerization domain,HMMPfam_P53,HMMPfam_P53_TAD	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA
ZNF681	0	genome.wustl.edu	36	19	23719583	23719584	+	Frame_Shift_Del	DEL	CA	CA	-	rs61397759		TCGA-AB-2860-03B-01W-0728-08	TCGA-AB-2860-11B-01W-0729-08	CA	CA	CA	-	CA	CA	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	3b8b7cea-9e19-426f-9e58-d40de477ce12	a9f714a7-2581-4ce0-b077-3db990730b27	19	23719583	23719584	CA	-	DEL	ZNF681	NM_138286.2	human	genbank	54_36p	-1	validated	frame_shift_del	c.609_608	p.C203fs	1.000:0.998	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	0	0	0.00	0	0	0.00	0	0	0.00