Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
SMC1A	0	genome.wustl.edu	36	X	53425957	53425957	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	X	53425957	53425957	T	C	SNP	SMC1A	NM_006306.2	human	genbank	54_36p	-1	reviewed	missense	c.3358	p.K1120E	1.000	HMMPfam_SMC_N,superfamily_SSF52540	HMMPfam_SMC_N,HMMPfam_SMC_hinge,superfamily_SMC_hinge,superfamily_SSF52540	-	no_errors	117	4	3.31	87	42	32.56	34	62	64.58
GBP4	0	genome.wustl.edu	36	1	89425289	89425289	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	1	89425289	89425289	C	T	SNP	GBP4	NM_052941.4	human	genbank	54_36p	-1	validated	missense	c.1495	p.G499R	0.001	HMMPfam_GBP_C,superfamily_GBP	HMMPfam_GBP_C,HMMPfam_GBP,superfamily_GBP,superfamily_SSF52540	-	no_errors	194	8	3.96	161	78	32.64	19	21	52.50
CORIN	0	genome.wustl.edu	36	4	47361825	47361825	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	4	47361825	47361825	C	T	SNP	CORIN	NM_006587.2	human	genbank	54_36p	-1	reviewed	missense	c.1570	p.E524K	0.119	superfamily_Frizzled cysteine-rich domain,HMMPfam_Fz,HMMSmart_SM00063	superfamily_Frizzled cysteine-rich domain,PatternScan_SRCR_1,HMMPfam_Trypsin,HMMSmart_SM00020,HMMPfam_Ldl_recept_a,HMMSmart_SM00192,PatternScan_LDLRA_1,superfamily_LDL receptor-like module,superfamily_Trypsin-like serine proteases,HMMSmart_SM00202,superfamily_SRCR-like,PatternScan_TRYPSIN_SER,HMMPfam_Fz,HMMSmart_SM00063	-	no_errors	148	5	3.25	72	37	33.94	NA	NA	NA
RAPGEF2	0	genome.wustl.edu	36	4	160463047	160463047	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	4	160463047	160463047	G	T	SNP	RAPGEF2	NM_014247.2	human	genbank	54_36p	+1	validated	nonsense	c.469	p.E157*	1.000	HMMPfam_cNMP_binding,HMMSmart_cNMP,superfamily_cNMP_binding	HMMPfam_RA,HMMSmart_RA,HMMPfam_cNMP_binding,HMMSmart_cNMP,HMMPfam_RasGEF_N,HMMSmart_RasGEFN,HMMPfam_PDZ,HMMSmart_PDZ,superfamily_PDZ,HMMPfam_RasGEF,HMMSmart_RasGEF,superfamily_Ras_GEF,superfamily_cNMP_binding	-	no_errors	163	6	3.49	164	69	29.61	4	5	55.56
PCDHB9	0	genome.wustl.edu	36	5	140549322	140549322	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	5	140549322	140549322	C	T	SNP	PCDHB9	NM_019119.3	human	genbank	54_36p	+1	reviewed	missense	c.2246	p.T749I	0.141	NULL	HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_Cadherin_2,superfamily_Cadherin-like	-	pseudogene:no_stop_codon:bad_bp_length_for_coding_region	79	4	4.82	74	29	28.16	NA	NA	NA
ZSCAN21	0	genome.wustl.edu	36	7	99492574	99492574	+	Silent	SNP	C	C	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	7	99492574	99492574	C	T	SNP	ZSCAN21	NM_145914.2	human	genbank	54_36p	+1	validated	silent	c.9	p.T3	0.942	NULL	HMMPfam_SCAN,HMMSmart_SM00431,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	50	2	3.70	80	22	21.36	4	6	60.00
DNAI1	0	genome.wustl.edu	36	9	34504416	34504416	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	9	34504416	34504416	T	C	SNP	DNAI1	NM_012144.2	human	genbank	54_36p	+1	reviewed	missense	c.1594	p.F532L	1.000	HMMSmart_WD40,superfamily_WD40_like,HMMPfam_WD40	HMMSmart_WD40,superfamily_WD40_like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	65	2	2.99	84	44	34.38	NA	NA	NA
PRF1	0	genome.wustl.edu	36	10	72030188	72030188	+	Silent	SNP	G	G	A			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	10	72030188	72030188	G	A	SNP	PRF1	NM_001083116.1	human	genbank	54_36p	-1	reviewed	silent	c.477	p.A159	0.008	HMMPfam_MACPF	HMMPfam_C2,HMMSmart_SM00239,HMMPfam_MACPF,HMMSmart_SM00457,PatternScan_MAC_PERFORIN,superfamily_C2 domain (Calcium/lipid-binding domain CaLB)	-	no_errors	106	5	4.46	189	98	34.15	16	0	0.00
WAPAL	0	genome.wustl.edu	36	10	88267726	88267726	+	Missense_Mutation	SNP	T	T	G			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	T	T	T	G	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	10	88267726	88267726	T	G	SNP	WAPAL	NM_015045.2	human	genbank	54_36p	-1	validated	missense	c.81	p.K27N	1.000	NULL	HMMPfam_WAPL,superfamily_ARM repeat	-	no_errors	118	4	3.23	116	64	35.56	47	32	40.51
DCDC5	0	genome.wustl.edu	36	11	30895090	30895090	+	Missense_Mutation	SNP	A	A	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	11	30895090	30895090	A	T	SNP	DCDC5	ENST00000406071	human	ensembl	54_36p	-1	known	missense	c.685	p.W229R	1.000	NULL	HMMPfam_DCX,superfamily_RicinB_like,superfamily_SSF89837	-	no_errors	119	10	7.69	104	37	26.24	NA	NA	NA
GRIK4	0	genome.wustl.edu	36	11	120338459	120338459	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	11	120338459	120338459	G	A	SNP	GRIK4	NM_014619.2	human	genbank	54_36p	+1	reviewed	missense	c.2125	p.G709R	1.000	HMMPfam_Lig_chan,HMMSmart_PBPe,superfamily_SSF53850	HMMPfam_Lig_chan,HMMSmart_PBPe,HMMPfam_ANF_receptor,HMMPfam_Lig_chan-Glu_bd,superfamily_SSF53822,superfamily_SSF53850	-	no_errors	56	0	0.00	44	18	29.03	1	0	0.00
C12orf63	0	genome.wustl.edu	36	12	95674471	95674471	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	12	95674471	95674471	G	A	SNP	C12orf63	NM_198520.2	human	genbank	54_36p	+1	validated	missense	c.3220	p.G1074R	1.000	NULL	NULL	-	no_errors	227	13	5.31	181	66	26.72	NA	NA	NA
IGHG3	0	genome.wustl.edu	36	14	105305233	105305233	+	Silent	SNP	A	A	G			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	14	105305233	105305233	A	G	SNP	IGHG3	ENST00000390550	human	ensembl	54_36p	-1	known	silent	c.1218	p.C406	1.000	NULL	PatternScan_IG_MHC,HMMPfam_C1-set,HMMSmart_SM00407,superfamily_Immunoglobulin	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	41	0	0.00	54	9	14.29	0	1	100.00
SLTM	0	genome.wustl.edu	36	15	56966894	56966894	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	15	56966894	56966894	A	G	SNP	SLTM	NM_024755.1	human	genbank	54_36p	-1	validated	missense	c.2513	p.L838P	1.000	NULL	HMMPfam_RRM_1,HMMSmart_RRM,HMMPfam_SAP,HMMSmart_SAP,superfamily_SSF54928,superfamily_SSF68906	-	no_errors	250	8	3.08	234	114	32.76	125	82	39.61
CACNG4	0	genome.wustl.edu	36	17	62457324	62457324	+	Silent	SNP	C	C	T			TCGA-AB-2858-03D-01W-0755-09	TCGA-AB-2858-12A-01W-0755-09	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	b9dcb0aa-0098-49a9-a0c8-790a06dadea8	d964bbe3-75e8-47d6-a495-505ff49b9f2b	17	62457324	62457324	C	T	SNP	CACNG4	NM_014405.2	human	genbank	54_36p	+1	reviewed	silent	c.726	p.R242	0.999	NULL	HMMPfam_PMP22_Claudin,PatternScan_CLAUDIN	-	no_errors	244	7	2.76	206	88	29.93	NA	NA	NA