Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
GYG2	0	genome.wustl.edu	36	X	2803884	2803884	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	X	2803884	2803884	G	A	SNP	GYG2	NM_003918.1	human	genbank	54_36p	+1	validated	missense	c.1165	p.V389M	0.001	NULL	HMMPfam_Glyco_transf_8,superfamily_Nucleotide-diphospho-sugar transferases	-	no_errors	58	2	3.33	69	34	33.01	NA	NA	NA
SCML2	0	genome.wustl.edu	36	X	18252971	18252971	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	X	18252971	18252971	C	A	SNP	SCML2	NM_006089.2	human	genbank	54_36p	-1	validated	missense	c.139	p.A47S	1.000	HMMSmart_SM00561,superfamily_Tudor/PWWP/MBT	HMMPfam_SAM_1,HMMSmart_SM00454,HMMPfam_MBT,HMMSmart_SM00561,superfamily_SAM/Pointed domain,superfamily_Tudor/PWWP/MBT	-	no_errors	33	3	8.11	51	34	40.00	22	0	0.00
TBC1D8B	0	genome.wustl.edu	36	X	105956093	105956093	+	Missense_Mutation	SNP	T	T	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	X	105956093	105956093	T	A	SNP	TBC1D8B	NM_017752.2	human	genbank	54_36p	+1	validated	missense	c.1005	p.N335K	0.976	HMMPfam_GRAM,HMMSmart_SM00568	HMMPfam_TBC,HMMSmart_SM00164,superfamily_Ypt/Rab-GAP domain of gyp1p,HMMPfam_GRAM,HMMSmart_SM00568,PatternScan_EF_HAND_1,superfamily_EF-hand	-	no_errors	19	0	0.00	125	31	19.87	4	0	0.00
AIFM1	0	genome.wustl.edu	36	X	129111222	129111222	+	Silent	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	X	129111222	129111222	G	A	SNP	AIFM1	NM_004208.1	human	genbank	54_36p	-1	reviewed	silent	c.252	p.A84	1.000	NULL	HMMPfam_Pyr_redox_2,superfamily_FAD/NAD-linked reductases dimerisation (C-terminal) domain,superfamily_FAD/NAD(P)-binding domain	-	no_errors	141	3	2.08	53	24	31.17	33	0	0.00
ATP11C	0	genome.wustl.edu	36	X	138641542	138641542	+	Silent	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	X	138641542	138641542	G	A	SNP	ATP11C	NM_173694.1	human	genbank	54_36p	-1	validated	silent	c.3336	p.S1112	0.956	NULL	HMMPfam_E1-E2_ATPase,PatternScan_ATPASE_E1_E2,superfamily_HAD-like,superfamily_Calcium ATPase transduction domain A,superfamily_Metal cation-transporting ATPase ATP-binding domain N	-	no_errors	62	0	0.00	96	15	13.51	4	0	0.00
MECR	0	genome.wustl.edu	36	1	29415717	29415717	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	1	29415717	29415717	T	C	SNP	MECR	NM_016011.1	human	genbank	54_36p	-1	validated	missense	c.244	p.I82V	0.997	superfamily_GroES-like,HMMPfam_ADH_N	superfamily_GroES-like,HMMPfam_ADH_zinc_N,HMMPfam_ADH_N,superfamily_NAD(P)-binding Rossmann-fold domains	-	no_errors	290	4	1.36	59	18	23.38	15	13	46.43
DNMT3A	0	genome.wustl.edu	36	2	25310746	25310746	+	Missense_Mutation	SNP	C	C	G			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	C	C	C	G	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	2	25310746	25310746	C	G	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2645	p.R882P	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	155	12	7.14	48	13	21.31	37	23	37.70
SH3BP4	0	genome.wustl.edu	36	2	235615512	235615512	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	2	235615512	235615512	G	A	SNP	SH3BP4	NM_014521.2	human	genbank	54_36p	+1	reviewed	missense	c.1360	p.V454M	0.948	NULL	HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMPfam_SH3_2	-	no_errors	22	0	0.00	50	10	16.67	NA	NA	NA
THRB	0	genome.wustl.edu	36	3	24144126	24144126	+	Missense_Mutation	SNP	G	G	A	rs121918697		TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	3	24144126	24144126	G	A	SNP	THRB	NM_000461.4	human	genbank	54_36p	-1	reviewed	missense	c.1012	p.R338W	0.991	HMMPfam_Hormone_recep,HMMSmart_SM00430,superfamily_Nuclear receptor ligand-binding domain	HMMPfam_Hormone_recep,HMMSmart_SM00430,HMMPfam_zf-C4,HMMSmart_SM00399,PatternScan_NUCLEAR_REC_DBD_1,superfamily_Nuclear receptor ligand-binding domain,superfamily_Glucocorticoid receptor-like (DNA-binding domain)	-	no_errors	117	11	8.59	86	19	18.10	NA	NA	NA
HIVEP2	0	genome.wustl.edu	36	6	143135644	143135644	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	6	143135644	143135644	C	T	SNP	HIVEP2	NM_006734.3	human	genbank	54_36p	-1	provisional	missense	c.1925	p.R642Q	0.983	NULL	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	46	4	7.84	62	33	34.74	18	3	14.29
FAM208B	0	genome.wustl.edu	36	10	5812591	5812591	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	10	5812591	5812591	G	A	SNP	C10orf18	NM_017782.3	human	genbank	54_36p	+1	validated	missense	c.623	p.R208H	0.005	NULL	NULL	-	no_errors	77	0	0.00	72	21	22.58	19	18	48.65
PHC1P1	0	genome.wustl.edu	36	12	54092397	54092397	+	Silent	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	12	54092397	54092397	G	A	SNP	PHC1B	ENST00000326184	human	ensembl	54_36p	-1	known	silent	c.2391	p.L797	0.250	HMMPfam_zf-FCS	HMMPfam_SAM_1,HMMSmart_SM00454,HMMPfam_zf-FCS,superfamily_SAM/Pointed domain	-	no_errors	16	1	5.88	25	11	30.56	41	0	0.00
MAPKBP1	0	genome.wustl.edu	36	15	39891521	39891521	+	Silent	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	15	39891521	39891521	G	A	SNP	MAPKBP1	NM_014994.1	human	genbank	54_36p	+1	validated	silent	c.402	p.K134	0.999	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	HMMSmart_SM00320,PatternScan_PTS_HPR_SER,superfamily_WD40 repeat-like,HMMPfam_WD40	-	no_errors	260	11	4.06	65	33	33.67	24	32	57.14
ABCC11	0	genome.wustl.edu	36	16	46802498	46802498	+	Silent	SNP	G	G	A			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	16	46802498	46802498	G	A	SNP	ABCC11	NM_032583.3	human	genbank	54_36p	-1	reviewed	silent	c.1470	p.I490	0.000	superfamily_Multidrug resistance ABC transporter MsbA N-terminal domain	HMMPfam_ABC_membrane,HMMPfam_ABC_tran,HMMSmart_SM00382,superfamily_Multidrug resistance ABC transporter MsbA N-terminal domain,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	184	17	8.42	117	61	34.27	NA	NA	NA
TUBGCP6	0	genome.wustl.edu	36	22	49013906	49013906	+	Missense_Mutation	SNP	A	A	G			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	A	A	A	G	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	22	49013906	49013906	A	G	SNP	TUBGCP6	NM_020461.3	human	genbank	54_36p	-1	reviewed	missense	c.1082	p.I361T	0.999	HMMPfam_Spc97_Spc98	HMMPfam_Spc97_Spc98	-	no_errors	38	1	2.56	30	12	28.57	68	50	42.37
TET2	0	genome.wustl.edu	36	4	106410312	106410313	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	4	106410312	106410313	-	G	INS	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_ins	c.547_548	p.A183fs	1.000:1.000	NULL	NULL	-	no_start_codon	30	0	0.00	98	0	0.00	12	0	0.00
TET2	0	genome.wustl.edu	36	4	106413304	106413304	+	Frame_Shift_Del	DEL	A	A	-			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	A	A	A	-	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	4	106413304	106413304	A	-	DEL	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	frame_shift_del	c.723	p.K241fs	0.000	NULL	NULL	-	no_start_codon	36	0	0.00	123	0	0.00	35	0	0.00
FLT3	0	genome.wustl.edu	36	13	27506242	27506243	+	In_Frame_Ins	INS	-	-	ACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTACCCCCTCGGGGGG			TCGA-AB-2830-03B-01W-0728-08	TCGA-AB-2830-11B-01W-0728-08	-	-	-	ACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTACCCCCTCGGGGGG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	f72fb885-99dd-486a-8f06-cf886c085f60	303971a6-646d-43e9-aa4c-18a133db1161	13	27506242	27506243	-	ACTCCCATTTGAGATCATATTCATATTCTCTGAAATCAACGTAGAAGTACTCATTACCCCCTCGGGGGG	INS	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	in_frame_ins	c.1814_1813	p.605in_frame_insSPRGGNEYFYVDFREYEYDLKWE	1.000:1.000	superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA