Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
USP34	0	genome.wustl.edu	36	2	61301042	61301042	+	Nonsense_Mutation	SNP	G	G	A			TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	2	61301042	61301042	G	A	SNP	USP34	NM_014709.3	human	genbank	54_36p	-1	validated	nonsense	c.7954	p.R2652*	1.000	NULL	HMMPfam_UCH,PatternScan_UCH_2_1,PatternScan_UCH_2_2,superfamily_Cysteine proteinases	-	no_errors	87	4	4.40	137	51	26.84	35	7	16.28
KDR	0	genome.wustl.edu	36	4	55650951	55650951	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	4	55650951	55650951	C	T	SNP	KDR	NM_002253.2	human	genbank	54_36p	-1	validated	missense	c.3121	p.V1041M	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,HMMSmart_IGc2,HMMSmart_IG,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_I-set,HMMPfam_V-set,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	137	13	8.67	118	92	43.81	NA	NA	NA
LOC643932	0	genome.wustl.edu	36	5	78616032	78616032	+	RNA	SNP	T	T	C			TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	5	78616032	78616032	T	C	SNP	LOC643932	XR_017289.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	1.000	-	-	-	pseudogene	117	9	7.14	120	107	46.32	2	1	33.33
KRAS	0	genome.wustl.edu	36	12	25271542	25271542	+	Missense_Mutation	SNP	T	T	A	rs17851045		TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	T	T	T	A	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	12	25271542	25271542	T	A	SNP	KRAS	NM_033360.3	human	genbank	54_36p	-1	reviewed	missense	c.183	p.Q61H	1.000	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	61	5	7.58	80	26	24.53	12	4	25.00
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	71	4	5.26	60	47	43.93	145	101	40.89
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2826-03B-01W-0728-08	TCGA-AB-2826-11B-01W-0728-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	94c3b46a-19ad-4292-82c6-bd1790725616	80181e62-a10e-426c-adac-623bed8e1a60	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA