Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ADD2	0	genome.wustl.edu	37	2	70905912	70905912	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	70905912	70905912	G	A	SNP	ADD2	ENST00000264436	human	ensembl	74_37	-1	known	missense	c.1307	p.T436M	0.990	NULL	pfam_Aldolase_II/adducin_N,superfamily_Aldolase_II/adducin_N	-	no_errors	ADD2	HGNC	ENSG00000075340	tier1	rs201022450	-	59	0	0.00	28	7	20.00
ANKS1B	0	genome.wustl.edu	37	12	100205934	100205934	+	Missense_Mutation	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	100205934	100205934	T	C	SNP	ANKS1B	ENST00000329257	human	ensembl	74_37	-1	known	missense	c.371	p.Q124R	1.000	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_SAM_type1,pfam_PTB/PI_dom,pfam_SAM_2,pfam_PTB,superfamily_Ankyrin_rpt-contain_dom,superfamily_SAM/pointed,smart_Ankyrin_rpt,smart_SAM,smart_PTB/PI_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_PTB/PI_dom,pfscan_SAM,prints_Ankyrin_rpt	-	no_errors	ANKS1B	HGNC	ENSG00000185046	tier1	-	-	60	0	0.00	70	5	6.67
ASCC3	0	genome.wustl.edu	37	6	101103625	101103625	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	101103625	101103625	G	A	SNP	ASCC3	ENST00000369162	human	ensembl	74_37	-1	known	missense	c.2773	p.R925W	1.000	NULL	pfam_Sec63-dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase/UvrB_dom,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_AAA+_ATPase,smart_Helicase_C,smart_Sec63-dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ASCC3	HGNC	ENSG00000112249				17	0	0.00	14	2	12.50
ASPM	0	genome.wustl.edu	37	1	197057452	197057452	+	Silent	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	197057452	197057452	G	T	SNP	ASPM	ENST00000367409	human	ensembl	74_37	-1	known	silent	c.10095	p.G3365	0.856	NULL	pfam_IQ_motif_EF-hand-BS,pfam_CAMSAP_CH,pfam_CH-domain,superfamily_CH-domain,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_CH-domain,smart_IQ_motif_EF-hand-BS,pfscan_CH-domain,pfscan_IQ_motif_EF-hand-BS	-	no_errors	ASPM	HGNC	ENSG00000066279				33	0	0.00	43	3	6.52
ATHL1	0	genome.wustl.edu	37	11	292904	292904	+	Nonsense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	292904	292904	G	T	SNP	ATHL1	ENST00000409548	human	ensembl	74_37	+1	known	nonsense	c.1177	p.E393*	0.589	pfam_Glyco_hydro_65_M,superfamily_6-hairpin_glycosidase-like	pfam_Glyco_hydro_65_M,superfamily_6-hairpin_glycosidase-like	-	no_errors	ATHL1	HGNC	ENSG00000142102	tier1	-	-	53	0	0.00	44	4	8.33
BMS1P18	0	genome.wustl.edu	37	14	19904273	19904273	+	RNA	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	14	19904273	19904273	C	T	SNP	BMS1P18	ENST00000549877	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	BMS1P18	HGNC	ENSG00000215394	tier1	-	-	60	0	0.00	35	9	20.45
C10orf112	0	genome.wustl.edu	37	10	19569057	19569057	+	Missense_Mutation	SNP	A	A	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	19569057	19569057	A	C	SNP	C10orf112	ENST00000454679	human	ensembl	74_37	+1	known	missense	c.1049	p.E350A	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt	pfam_MAM_dom,pfam_LDrepeatLR_classA_rpt,superfamily_ConA-like_lec_gl_sf,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_MAM_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_MAM_dom,prints_LDrepeatLR_classA_rpt,prints_MAM_dom	-	no_errors	C10orf112	HGNC	ENSG00000204740	tier1	-	-	30	0	0.00	13	14	51.85
CALM3	0	genome.wustl.edu	37	19	47112420	47112420	+	RNA	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	47112420	47112420	G	A	SNP	CALM3	ENST00000477244	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CALM3	HGNC	ENSG00000160014	tier1	-	-	61	0	0.00	30	23	43.40
CASP12	0	genome.wustl.edu	37	11	104761930	104761930	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	104761930	104761930	G	A	SNP	CASP12	ENST00000375726	human	ensembl	74_37	-1	known	missense	c.634	p.P212S	1.000	pfam_Pept_C14_caspase,smart_Pept_C14A_p45_core,pirsf_Caspase_IL-1_beta,pfscan_Pept_C14_ICE_p20,prints_Pept_C14A_p45_core	pfam_Pept_C14_caspase,pfam_CARD,superfamily_DEATH-like_dom,smart_Pept_C14A_p45_core,pirsf_Caspase_IL-1_beta,pfscan_CARD,pfscan_Pept_C14_p10,pfscan_Pept_C14_ICE_p20,prints_Pept_C14A_p45_core	-	no_errors	CASP12	HGNC	ENSG00000204403	tier1	-	-	63	0	0.00	42	10	19.23
CCDC62	0	genome.wustl.edu	37	12	123285733	123285733	+	Missense_Mutation	SNP	A	A	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	123285733	123285733	A	C	SNP	CCDC62	ENST00000253079	human	ensembl	74_37	+1	known	missense	c.1040	p.K347T	0.994	NULL	superfamily_Prefoldin	-	no_errors	CCDC62	HGNC	ENSG00000130783	tier1	-	-	32	0	0.00	23	15	39.47
CCL20	0	genome.wustl.edu	37	2	228680154	228680154	+	RNA	DEL	T	T	-			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	228680154	228680154	T	-	DEL	CCL20	ENST00000473642	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.010	-	-	-	no_errors	CCL20	HGNC	ENSG00000115009	tier1			8	0	0.00	10	2	16.67
CD1B	0	genome.wustl.edu	37	1	158299185	158299185	+	Missense_Mutation	SNP	C	C	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	158299185	158299185	C	A	SNP	CD1B	ENST00000368168	human	ensembl	74_37	-1	known	missense	c.861	p.E287D	0.113	pfam_Ig_C1-set,smart_Ig_C1-set	pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	CD1B	HGNC	ENSG00000158485	tier1	-	-	50	0	0.00	38	11	22.45
CDH9	0	genome.wustl.edu	37	5	26915767	26915767	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	5	26915767	26915767	G	T	SNP	CDH9	ENST00000231021	human	ensembl	74_37	-1	known	missense	c.494	p.T165N	1.000	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH9	HGNC	ENSG00000113100	tier1	-	-	19	0	0.00	8	3	27.27
CLDN16	0	genome.wustl.edu	37	3	190127745	190127745	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	190127745	190127745	G	A	SNP	CLDN16	ENST00000264734	human	ensembl	74_37	+1	known	missense	c.838	p.A280T	0.000	NULL	pfam_PMP22/EMP/MP20/Claudin,prints_Claudin16,prints_Claudin	-	no_errors	CLDN16	HGNC	ENSG00000113946	tier1	-	-	63	0	0.00	47	11	18.97
COL4A5	0	genome.wustl.edu	37	X	107802335	107802335	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	X	107802335	107802335	G	T	SNP	COL4A5	ENST00000328300	human	ensembl	74_37	+1	known	missense	c.183	p.L61F	1.000	NULL	pfam_Collagen,pfam_Collagen_VI_NC,superfamily_C-type_lectin_fold,smart_Collagen_VI_NC	-	no_errors	COL4A5	HGNC	ENSG00000188153	tier1	-	-	14	0	0.00	18	5	21.74
CSN3	0	genome.wustl.edu	37	4	71114982	71114982	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	4	71114982	71114982	G	T	SNP	CSN3	ENST00000304954	human	ensembl	74_37	+1	known	missense	c.355	p.A119S	0.005	pfam_Casein_kappa,pirsf_Casein_kappa	pfam_Casein_kappa,pirsf_Casein_kappa	-	no_errors	CSN3	HGNC	ENSG00000171209	tier1	-	-	29	0	0.00	15	4	21.05
CTSK	0	genome.wustl.edu	37	1	150779260	150779260	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	150779260	150779260	G	T	SNP	CTSK	ENST00000271651	human	ensembl	74_37	-1	known	missense	c.22	p.L8M	0.555	NULL	pfam_Peptidase_C1A_C,pfam_Prot_inhib_I29,pfam_Peptidase_C1B,smart_Prot_inhib_I29,smart_Peptidase_C1A_C,prints_Peptidase_C1A_C	-	no_errors	CTSK	HGNC	ENSG00000143387	tier1	-	-	43	0	0.00	26	5	16.13
CYB5RL	0	genome.wustl.edu	37	1	54640442	54640442	+	Silent	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	54640442	54640442	G	A	SNP	CYB5RL	ENST00000419823	human	ensembl	74_37	-1	known	silent	c.798	p.G266	1.000	pfam_OxRdtase_FAD/NAD-bd	pfam_OxRdtase_FAD-bd_dom,pfam_Oxidoreductase-like_N,pfam_OxRdtase_FAD/NAD-bd,superfamily_Riboflavin_synthase-like_b-brl,prints_NADH-Cyt_B5_reductase,prints_Phe_hydroxylase	-	no_errors	CYB5RL	HGNC	ENSG00000215883	tier1	-	-	39	0	0.00	74	4	5.13
CYP4F8	0	genome.wustl.edu	37	19	15726500	15726500	+	RNA	SNP	G	G	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	15726500	15726500	G	C	SNP	CYP4F8	ENST00000325723	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.934	-	-	-	no_errors	CYP4F8	HGNC	ENSG00000186526	tier1	-	-	78	0	0.00	56	19	25.33
DCC	0	genome.wustl.edu	37	18	50961530	50961530	+	Silent	SNP	A	A	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	18	50961530	50961530	A	C	SNP	DCC	ENST00000442544	human	ensembl	74_37	+1	known	silent	c.3180	p.G1060	0.997	NULL	pfam_Neogenin_C,pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DCC	HGNC	ENSG00000187323	tier1	-	-	35	0	0.00	14	19	57.58
DENND1A	0	genome.wustl.edu	37	9	126144060	126144060	+	Missense_Mutation	SNP	T	T	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	9	126144060	126144060	T	G	SNP	DENND1A	ENST00000394219	human	ensembl	74_37	-1	known	missense	c.2714	p.N905T	0.994	NULL	pfam_DENN_dom,pfam_dDENN_dom,pfam_uDENN_dom,smart_uDENN_dom,smart_DENN_dom,smart_dDENN_dom,pfscan_DENN_dom,pfscan_uDENN_dom,pfscan_dDENN_dom	-	no_errors	DENND1A	HGNC	ENSG00000119522	tier1	-	-	82	0	0.00	66	9	12.00
DNA2	0	genome.wustl.edu	37	10	70231769	70231770	+	Frame_Shift_Ins	INS	-	-	GT			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	70231769	70231770	-	GT	INS	DNA2	ENST00000399180	human	ensembl	74_37	-1	known	frame_shift_ins	c.111_110	p.P38fs	0.000:0.000	NULL	pfam_DNA_replication_fac_Dna2_N,superfamily_P-loop_NTPase	-	no_errors	DNA2	HGNC	ENSG00000138346	tier1			31	0	0.00	7	2	22.22
DNAH9	0	genome.wustl.edu	37	17	11757419	11757419	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	11757419	11757419	C	T	SNP	DNAH9	ENST00000262442	human	ensembl	74_37	+1	known	missense	c.9607	p.P3203S	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH9	HGNC	ENSG00000007174	tier1	-	-	44	0	0.00	28	8	22.22
DNM1P46	0	genome.wustl.edu	37	15	100331592	100331592	+	RNA	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	15	100331592	100331592	G	A	SNP	DNM1P46	ENST00000341853	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.029	-	-	-	no_errors	DNM1P46	HGNC	ENSG00000182397	tier1	-	-	35	0	0.00	24	9	27.27
DYSF	0	genome.wustl.edu	37	2	71755483	71755483	+	Silent	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	71755483	71755483	G	A	SNP	DYSF	ENST00000413539	human	ensembl	74_37	+1	known	silent	c.1329	p.K443	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,pfam_Ferlin_A-domain,superfamily_C2_dom,superfamily_MFS_dom_general_subst_transpt,smart_C2_dom,smart_Peroxin/Ferlin,pfscan_C2_dom	-	no_errors	DYSF	HGNC	ENSG00000135636	tier1	-	-	49	0	0.00	34	6	15.00
ECEL1	0	genome.wustl.edu	37	2	233349744	233349744	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	233349744	233349744	C	T	SNP	ECEL1	ENST00000304546	human	ensembl	74_37	-1	known	missense	c.913	p.A305T	0.001	pfam_Peptidase_M13_N	pfam_Peptidase_M13_N,pfam_Peptidase_M13_C,prints_Peptidase_M13_C	-	no_errors	ECEL1	HGNC	ENSG00000171551	tier1	-	-	31	0	0.00	22	8	26.67
ELF2	0	genome.wustl.edu	37	4	140046348	140046348	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	4	140046348	140046348	G	T	SNP	ELF2	ENST00000379550	human	ensembl	74_37	-1	known	missense	c.208	p.Q70K	1.000	pfam_TF_Elf_N	pfam_TF_Elf_N,pfam_Ets_dom,smart_Ets_dom,pfscan_Ets_dom,prints_Ets_dom	-	no_errors	ELF2	HGNC	ENSG00000109381				48	0	0.00	29	2	6.45
ELOVL3	0	genome.wustl.edu	37	10	103988606	103988606	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	103988606	103988606	G	A	SNP	ELOVL3	ENST00000370005	human	ensembl	74_37	+1	known	missense	c.410	p.R137H	0.995	pfam_GNS1_SUR4	pfam_GNS1_SUR4	-	no_errors	ELOVL3	HGNC	ENSG00000119915	tier1	rs149375895	-	50	0	0.00	20	8	28.57
ENSG00000232807	0	genome.wustl.edu	37	10	5978975	5978975	+	RNA	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	5978975	5978975	G	T	SNP	ENSG00000232807	ENST00000397264	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-536K7.3	Clone_based_vega_gene	ENSG00000232807	tier1	-	-	84	0	0.00	69	4	5.48
FAM71E2	0	genome.wustl.edu	37	19	55869940	55869940	+	Nonsense_Mutation	SNP	T	T	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	55869940	55869940	T	A	SNP	FAM71E2	ENST00000424985	human	ensembl	74_37	-1	novel	nonsense	c.2296	p.K766*	0.023	NULL	pfam_DUF3699	-	no_errors	FAM71E2	HGNC	ENSG00000180043	tier1	-	-	61	0	0.00	69	8	10.39
FANCM	0	genome.wustl.edu	37	14	45623962	45623962	+	Silent	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	14	45623962	45623962	C	T	SNP	FANCM	ENST00000267430	human	ensembl	74_37	+1	known	silent	c.1246	p.L416	1.000	superfamily_P-loop_NTPase	pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,superfamily_Restrct_endonuc-II-like,superfamily_RuvA_2-like,smart_Helicase_ATP-bd,smart_Helicase_C,smart_ERCC4_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	FANCM	HGNC	ENSG00000187790	tier1	-	-	38	0	0.00	27	11	28.95
FSCN2	0	genome.wustl.edu	37	17	79502077	79502077	+	Splice_Site	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	79502077	79502077	G	T	SNP	FSCN2	ENST00000334850	human	ensembl	74_37	+1	known	splice_site	c.827-1	e2-1	1.000	-	-	-	no_errors	FSCN2	HGNC	ENSG00000186765				14	0	0.00	12	4	23.53
GBX2	0	genome.wustl.edu	37	2	237074959	237074959	+	Silent	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	237074959	237074959	G	T	SNP	GBX2	ENST00000306318	human	ensembl	74_37	-1	known	silent	c.645	p.G215	1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa	-	no_errors	GBX2	HGNC	ENSG00000168505				32	0	0.00	19	4	17.39
GLIPR1L2	0	genome.wustl.edu	37	12	75804346	75804346	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	75804346	75804346	G	T	SNP	GLIPR1L2	ENST00000550916	human	ensembl	74_37	+1	known	missense	c.367	p.G123C	0.988	pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1	pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1,prints_Allrgn_V5/Tpx1	-	no_errors	GLIPR1L2	HGNC	ENSG00000180481				37	0	0.00	35	2	5.41
GON4L	0	genome.wustl.edu	37	1	155785777	155785777	+	RNA	DEL	A	A	-			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	155785777	155785777	A	-	DEL	GON4L	ENST00000471341	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	GON4L	HGNC	ENSG00000116580	tier1			16	0	0.00	26	6	18.75
GRIN2A	0	genome.wustl.edu	37	16	9943750	9943750	+	Silent	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	16	9943750	9943750	G	A	SNP	GRIN2A	ENST00000330684	human	ensembl	74_37	-1	known	silent	c.1191	p.S397	0.001	NULL	pfam_NMDAR2_C,pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN2A	HGNC	ENSG00000183454				43	0	0.00	33	3	8.33
HADHA	0	genome.wustl.edu	37	2	26437990	26437990	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	26437990	26437990	G	T	SNP	HADHA	ENST00000380649	human	ensembl	74_37	-1	known	missense	c.731	p.A244E	1.000	tigrfam_Fa_ox_alpha_mit	pfam_Crotonase_core_superfam,pfam_3-OHacyl-CoA_DH_NAD-bd,pfam_3HC_DH_C,superfamily_6-PGluconate_DH_C-like,tigrfam_Fa_ox_alpha_mit	-	no_errors	HADHA	HGNC	ENSG00000084754				40	0	0.00	29	3	9.38
HHIP	0	genome.wustl.edu	37	4	145633170	145633171	+	Frame_Shift_Ins	INS	-	-	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	4	145633170	145633171	-	A	INS	HHIP	ENST00000296575	human	ensembl	74_37	+1	known	frame_shift_ins	c.1370_1371	p.N459fs	1.000:0.998	NULL	pfam_Folate_rcpt-like,superfamily_Quinoprot_gluc/sorb_DH,smart_EG-like_dom,pfscan_EG-like_dom	-	no_errors	HHIP	HGNC	ENSG00000164161	tier1			59	0	0.00	35	11	23.91
HIVEP2	0	genome.wustl.edu	37	6	143092631	143092631	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	143092631	143092631	C	T	SNP	HIVEP2	ENST00000012134	human	ensembl	74_37	-1	known	missense	c.3245	p.R1082Q	1.000	NULL	pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	HIVEP2	HGNC	ENSG00000010818	tier1	-	-	30	0	0.00	21	11	34.38
HIVEP2	0	genome.wustl.edu	37	6	143094119	143094119	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	143094119	143094119	G	A	SNP	HIVEP2	ENST00000012134	human	ensembl	74_37	-1	known	missense	c.1757	p.P586L	0.995	NULL	pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	HIVEP2	HGNC	ENSG00000010818				14	0	0.00	16	3	15.79
HYDIN	0	genome.wustl.edu	37	16	71054178	71054178	+	Missense_Mutation	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	16	71054178	71054178	T	C	SNP	HYDIN	ENST00000448089	human	ensembl	74_37	-1	known	missense	c.3085	p.I1029V	0.589	NULL	superfamily_PapD-like	-	no_errors	HYDIN	HGNC	ENSG00000157423				47	0	0.00	45	3	6.25
IRX5	0	genome.wustl.edu	37	16	54966722	54966722	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	16	54966722	54966722	G	A	SNP	IRX5	ENST00000394636	human	ensembl	74_37	+1	known	missense	c.562	p.E188K	1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,smart_Iroquois_homeo,pfscan_Homeobox_dom	-	no_errors	IRX5	HGNC	ENSG00000176842	tier1	-	-	71	0	0.00	38	14	26.92
ITPR2	0	genome.wustl.edu	37	12	26551892	26551892	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	26551892	26551892	C	T	SNP	ITPR2	ENST00000381340	human	ensembl	74_37	-1	known	missense	c.7613	p.G2538D	1.000	pfam_Ion_trans_dom	pfam_Ca-rel_channel,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ARM-type_fold,smart_MIR_motif,prints_InsP3_rcpt-bd,pfscan_MIR_motif	-	no_errors	ITPR2	HGNC	ENSG00000123104				40	0	0.00	23	2	8.00
KDELC1	0	genome.wustl.edu	37	13	103443257	103443257	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	13	103443257	103443257	G	T	SNP	KDELC1	ENST00000376004	human	ensembl	74_37	-1	known	missense	c.1077	p.F359L	1.000	pfam_LipoPS_modifying,smart_LipoPS_modifying	pfam_LipoPS_modifying,pfam_Filamin/ABP280_repeat-like,superfamily_Ig_E-set,smart_Filamin,smart_LipoPS_modifying,pfscan_Filamin/ABP280_repeat-like	-	no_errors	KDELC1	HGNC	ENSG00000134901	tier1	-	-	24	0	0.00	20	4	16.67
KIF1A	0	genome.wustl.edu	37	2	241680691	241680691	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	241680691	241680691	G	T	SNP	KIF1A	ENST00000498729	human	ensembl	74_37	-1	known	missense	c.3744	p.N1248K	0.652	NULL	pfam_Kinesin_motor_dom,pfam_Kinesin-like,pfam_Pleckstrin_homology,pfam_KIF1B,pfam_FHA_dom,superfamily_P-loop_NTPase,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,smart_FHA_dom,smart_Pleckstrin_homology,pfscan_FHA_dom,pfscan_Pleckstrin_homology,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF1A	HGNC	ENSG00000130294	tier1	-	-	22	0	0.00	13	3	18.75
KLHL32	0	genome.wustl.edu	37	6	97512566	97512566	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	97512566	97512566	G	T	SNP	KLHL32	ENST00000369261	human	ensembl	74_37	+1	known	missense	c.375	p.L125F	1.000	pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,pirsf_Kelch-like_gigaxonin	pfam_Kelch_1,pfam_BTB_POZ,pfam_BACK,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like	-	no_errors	KLHL32	HGNC	ENSG00000186231	tier1	-	-	39	0	0.00	34	4	10.53
KMT2C	0	genome.wustl.edu	37	7	151848559	151848559	+	Nonsense_Mutation	SNP	T	T	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	7	151848559	151848559	T	A	SNP	KMT2C	ENST00000355193	human	ensembl	74_37	-1	known	nonsense	c.12805	p.K4269*	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2C	HGNC	ENSG00000055609	tier1	-	-	33	0	0.00	5	12	70.59
LFNG	0	genome.wustl.edu	37	7	2565992	2565992	+	Silent	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	7	2565992	2565992	C	T	SNP	LFNG	ENST00000222725	human	ensembl	74_37	+1	known	silent	c.936	p.H312	1.000	pfam_Fringe-like,pirsf_Fringe	pfam_Fringe-like,pirsf_Fringe	-	no_errors	LFNG	HGNC	ENSG00000106003	tier1	-	-	39	0	0.00	37	11	22.92
LOC100509091	0	genome.wustl.edu	37	X	152752248	152752248	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	X	152752248	152752248	C	T	SNP	LOC100509091	ENST00000428676	human	ensembl	74_37	+1	putative	missense	c.358	p.R120W	0.008	NULL	pfam_Leu-rich_rpt	-	no_errors	U82695.9	Clone_based_vega_gene	ENSG00000224963	tier1	-	-	24	0	0.00	11	28	71.79
LRRN1	0	genome.wustl.edu	37	3	3886551	3886551	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	3886551	3886551	G	T	SNP	LRRN1	ENST00000319331	human	ensembl	74_37	+1	known	missense	c.226	p.V76L	1.000	NULL	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	LRRN1	HGNC	ENSG00000175928	tier1	-	-	35	0	0.00	20	10	33.33
MAP3K5	0	genome.wustl.edu	37	6	137018434	137018434	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	137018434	137018434	G	A	SNP	MAP3K5	ENST00000359015	human	ensembl	74_37	-1	known	missense	c.898	p.R300W	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_SAM/pointed,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	MAP3K5	HGNC	ENSG00000197442	tier1	-	-	29	0	0.00	18	9	33.33
MAPK15	0	genome.wustl.edu	37	8	144804294	144804294	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	8	144804294	144804294	G	A	SNP	MAPK15	ENST00000338033	human	ensembl	74_37	+1	known	missense	c.1508	p.S503N	0.012	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAPK15	HGNC	ENSG00000181085	tier1	-	-	35	0	0.00	9	4	30.77
MEGF8	0	genome.wustl.edu	37	19	42875612	42875612	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	42875612	42875612	G	A	SNP	MEGF8	ENST00000251268	human	ensembl	74_37	+1	known	missense	c.7247	p.R2416H	1.000	smart_EG-like_dom	pfam_CUB_dom,pfam_EGF_laminin,pfam_Plexin_repeat,superfamily_Gal_Oxase/kelch_b-propeller,superfamily_CUB_dom,superfamily_Plexin-like_fold,smart_CUB_dom,smart_EG-like_dom,smart_Plexin-like_fold,smart_EGF-like_Ca-bd_dom,smart_EGF_laminin,pfscan_CUB_dom,pfscan_EG-like_dom,pfscan_EGF_laminin	-	no_errors	MEGF8	HGNC	ENSG00000105429				39	0	0.00	36	2	5.26
MIDN	0	genome.wustl.edu	37	19	1255011	1255011	+	Silent	SNP	C	C	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	1255011	1255011	C	A	SNP	MIDN	ENST00000300952	human	ensembl	74_37	+1	known	silent	c.807	p.I269	0.994	NULL	pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup	-	no_errors	MIDN	HGNC	ENSG00000167470	tier1	-	-	47	0	0.00	6	7	53.85
MIPEP	0	genome.wustl.edu	37	13	24444223	24444223	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	13	24444223	24444223	G	A	SNP	MIPEP	ENST00000382172	human	ensembl	74_37	-1	known	missense	c.715	p.R239C	0.687	NULL	pfam_Pept_M3A_M3B	-	no_errors	MIPEP	HGNC	ENSG00000027001	tier1	-	-	57	0	0.00	47	9	16.07
MOV10	0	genome.wustl.edu	37	1	113234375	113234375	+	Nonsense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	113234375	113234375	C	T	SNP	MOV10	ENST00000357443	human	ensembl	74_37	+1	known	nonsense	c.925	p.Q309*	1.000	NULL	superfamily_P-loop_NTPase	-	no_errors	MOV10	HGNC	ENSG00000155363	tier1	-	-	79	0	0.00	42	14	25.00
MT-RNR1	0	genome.wustl.edu	37	MT	1204	1204	+	RNA	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	MT	1204	1204	C	T	SNP	MT-RNR1	ENST00000389680	human	ensembl	74_37	+1	known	rna	NULL	NULL	NULL	-	-	-	no_errors	MT-RNR1	HGNC	ENSG00000211459	tier1	-	-	24	0	0.00	4	2	33.33
MTMR10	0	genome.wustl.edu	37	15	31253135	31253135	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	15	31253135	31253135	G	T	SNP	MTMR10	ENST00000435680	human	ensembl	74_37	-1	known	missense	c.707	p.A236D	1.000	NULL	pfam_Myotubularin_assoc,pfam_Myotubularin-like_Pase_dom	-	no_errors	MTMR10	HGNC	ENSG00000166912	tier1	-	-	77	0	0.00	43	4	8.51
MUC16	0	genome.wustl.edu	37	19	9069914	9069914	+	Silent	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	9069914	9069914	G	T	SNP	MUC16	ENST00000397910	human	ensembl	74_37	-1	known	silent	c.17532	p.I5844	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom	-	no_errors	MUC16	HGNC	ENSG00000181143	tier1	-	-	106	0	0.00	65	17	20.73
MUC4	0	genome.wustl.edu	37	3	195481170	195481170	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	195481170	195481170	G	A	SNP	MUC4	ENST00000463781	human	ensembl	74_37	-1	known	missense	c.15242	p.P5081L	0.000	smart_EG-like_dom	pfam_Nidogen_extracell_dom,pfam_AMOP,pfam_VWF_type-D,smart_Nidogen_extracell_dom,smart_AMOP,smart_VWF_type-D,smart_EG-like_dom,pfscan_AMOP,pfscan_EG-like_dom	-	no_errors	MUC4	HGNC	ENSG00000145113	tier1	-	-	63	0	0.00	31	16	34.04
MUC5B	0	genome.wustl.edu	37	11	1267550	1267550	+	Missense_Mutation	SNP	C	C	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	1267550	1267550	C	G	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	missense	c.9449	p.A3150G	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983				91	0	0.00	42	4	8.51
MYD88	0	genome.wustl.edu	37	3	38180161	38180161	+	Silent	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	38180161	38180161	C	T	SNP	MYD88	ENST00000417037	human	ensembl	74_37	+1	known	silent	c.9	p.P3	0.000	NULL	pfam_TIR_dom,pfam_Death_domain,superfamily_DEATH-like_dom,superfamily_TIR_dom,smart_Death_domain,smart_TIR_dom,pirsf_Myelin_different_resp_MyD88,pfscan_Death_domain,pfscan_TIR_dom	-	no_errors	MYD88	HGNC	ENSG00000172936	tier1	-	-	33	0	0.00	16	10	38.46
MYH7	0	genome.wustl.edu	37	14	23891482	23891482	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	14	23891482	23891482	G	A	SNP	MYH7	ENST00000355349	human	ensembl	74_37	-1	known	missense	c.3152	p.A1051V	0.995	superfamily_Prefoldin	pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH7	HGNC	ENSG00000092054				79	0	0.00	54	4	6.90
MYO1F	0	genome.wustl.edu	37	19	8592306	8592306	+	Missense_Mutation	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	8592306	8592306	A	G	SNP	MYO1F	ENST00000338257	human	ensembl	74_37	-1	known	missense	c.2390	p.V797A	1.000	pfam_Myosin_tail_2	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,pfam_SH3_domain,pfam_SH3_2,superfamily_P-loop_NTPase,superfamily_SH3_domain,smart_Myosin_head_motor_dom,smart_SH3_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_SH3_domain,prints_Myosin_head_motor_dom,prints_SH3_domain	-	no_errors	MYO1F	HGNC	ENSG00000142347	tier1	-	-	63	0	0.00	30	13	30.23
NEB	0	genome.wustl.edu	37	2	152402931	152402931	+	Silent	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	152402931	152402931	G	T	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.20394	p.V6798	1.000	pfam_Nebulin_35r-motif,smart_Nebulin_35r-motif,pfscan_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091				19	0	0.00	36	3	7.69
NEDD4L	0	genome.wustl.edu	37	18	56002725	56002725	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	18	56002725	56002725	G	T	SNP	NEDD4L	ENST00000400345	human	ensembl	74_37	+1	known	missense	c.1081	p.G361W	1.000	NULL	pfam_HECT,pfam_WW_dom,pfam_C2_dom,superfamily_HECT,superfamily_C2_dom,superfamily_WW_dom,smart_C2_dom,smart_WW_dom,smart_HECT,pfscan_HECT,pfscan_C2_dom,pfscan_WW_dom,prints_C2_dom	-	no_errors	NEDD4L	HGNC	ENSG00000049759				39	0	0.00	28	2	6.67
NKD2	0	genome.wustl.edu	37	5	1037676	1037676	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	5	1037676	1037676	C	T	SNP	NKD2	ENST00000537972	human	ensembl	74_37	+1	known	missense	c.829	p.H277Y	0.002	NULL	pfscan_EF_hand_dom	-	no_errors	NKD2	HGNC	ENSG00000145506	tier1	-	-	45	0	0.00	16	7	30.43
NRXN3	0	genome.wustl.edu	37	14	80327445	80327445	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	14	80327445	80327445	G	A	SNP	NRXN3	ENST00000557594	human	ensembl	74_37	+1	novel	missense	c.1052	p.R351H	1.000	NULL	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_Neurexin-like,pfscan_Laminin_G	-	no_errors	NRXN3	HGNC	ENSG00000021645	tier1	-	-	69	0	0.00	57	4	6.56
NUP54	0	genome.wustl.edu	37	4	77055514	77055514	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	4	77055514	77055514	G	T	SNP	NUP54	ENST00000264883	human	ensembl	74_37	-1	known	missense	c.524	p.A175E	1.000	NULL	NULL	-	no_errors	NUP54	HGNC	ENSG00000138750	tier1	-	-	39	0	0.00	20	3	13.04
OR10A5	0	genome.wustl.edu	37	11	6867799	6867799	+	Missense_Mutation	SNP	A	A	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	6867799	6867799	A	T	SNP	OR10A5	ENST00000379831	human	ensembl	74_37	+1	known	missense	c.898	p.S300C	0.999	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10A5	HGNC	ENSG00000166363	tier1	-	-	31	0	0.00	27	10	27.03
OR4A47	0	genome.wustl.edu	37	11	48510925	48510925	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	48510925	48510925	G	T	SNP	OR4A47	ENST00000446524	human	ensembl	74_37	+1	known	missense	c.581	p.G194V	0.009	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4A47	HGNC	ENSG00000237388				65	0	0.00	50	3	5.66
OR4D2	0	genome.wustl.edu	37	17	56247408	56247408	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	56247408	56247408	G	A	SNP	OR4D2	ENST00000545221	human	ensembl	74_37	+1	known	missense	c.392	p.R131H	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4D2	HGNC	ENSG00000255713	tier1	rs147819968	-	46	0	0.00	21	21	50.00
OR5M9	0	genome.wustl.edu	37	11	56230100	56230100	+	Missense_Mutation	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	56230100	56230100	T	C	SNP	OR5M9	ENST00000279791	human	ensembl	74_37	-1	known	missense	c.778	p.R260G	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5M9	HGNC	ENSG00000150269	tier1	-	-	58	0	0.00	35	8	18.18
PCDH15	0	genome.wustl.edu	37	10	55782711	55782711	+	Missense_Mutation	SNP	T	T	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	55782711	55782711	T	G	SNP	PCDH15	ENST00000320301	human	ensembl	74_37	-1	known	missense	c.2467	p.T823P	0.954	superfamily_Cadherin-like,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275	tier1	-	-	56	0	0.00	20	14	40.00
PCDHAC2	0	genome.wustl.edu	37	5	140347423	140347423	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	5	140347423	140347423	G	A	SNP	PCDHAC2	ENST00000289269	human	ensembl	74_37	+1	known	missense	c.1072	p.V358M	1.000	superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHAC2	HGNC	ENSG00000243232	tier1	-	-	52	0	0.00	37	4	9.76
PCSK2	0	genome.wustl.edu	37	20	17462531	17462531	+	Missense_Mutation	SNP	C	C	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	20	17462531	17462531	C	G	SNP	PCSK2	ENST00000262545	human	ensembl	74_37	+1	known	missense	c.1733	p.A578G	0.009	pfam_PrprotnconvertsP,superfamily_Galactose-bd-like	pfam_Peptidase_S8/S53_dom,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53_dom,superfamily_Galactose-bd-like,superfamily_Prot_inh_propept,prints_Peptidase_S8_subtilisin-rel	-	no_errors	PCSK2	HGNC	ENSG00000125851	tier1	-	-	27	0	0.00	32	9	21.95
PDCD5	0	genome.wustl.edu	37	19	33076747	33076747	+	Silent	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	33076747	33076747	T	C	SNP	PDCD5	ENST00000590247	human	ensembl	74_37	+1	known	silent	c.192	p.P64	0.977	pfam_PDCD5-related,superfamily_PDCD5-related,pirsf_PDCD5-related	pfam_PDCD5-related,superfamily_PDCD5-related,pirsf_PDCD5-related	-	no_errors	PDCD5	HGNC	ENSG00000105185	tier1	-	-	32	0	0.00	51	4	7.27
PDDC1	0	genome.wustl.edu	37	11	771164	771164	+	RNA	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	771164	771164	G	T	SNP	PDDC1	ENST00000529966	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PDDC1	HGNC	ENSG00000177225	tier1	-	-	65	0	0.00	49	4	7.55
PDXK	0	genome.wustl.edu	37	21	45175962	45175962	+	RNA	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	21	45175962	45175962	C	T	SNP	PDXK	ENST00000343528	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PDXK	HGNC	ENSG00000160209	tier1	-	-	70	0	0.00	40	8	16.67
PHF12	0	genome.wustl.edu	37	17	27233372	27233372	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	27233372	27233372	G	T	SNP	PHF12	ENST00000332830	human	ensembl	74_37	-1	known	missense	c.2844	p.H948Q	1.000	NULL	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,superfamily_SMAD_FHA_domain,smart_Znf_PHD,pfscan_FHA_dom,pfscan_Znf_PHD-finger	-	no_errors	PHF12	HGNC	ENSG00000109118	tier1	-	-	26	0	0.00	29	8	21.62
PHRF1	0	genome.wustl.edu	37	11	597555	597555	+	Silent	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	11	597555	597555	G	A	SNP	PHRF1	ENST00000264555	human	ensembl	74_37	+1	known	silent	c.879	p.T293	0.013	NULL	pfam_Znf_PHD-finger,pfam_Znf_C3HC4_RING-type,superfamily_Znf_FYVE_PHD,smart_Znf_RING,smart_Znf_PHD,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	PHRF1	HGNC	ENSG00000070047				37	0	0.00	14	6	30.00
PIGQ	0	genome.wustl.edu	37	16	630954	630954	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	16	630954	630954	C	T	SNP	PIGQ	ENST00000026218	human	ensembl	74_37	+1	known	missense	c.1513	p.R505W	1.000	NULL	pfam_GlcNAc_Gpi1	-	no_errors	PIGQ	HGNC	ENSG00000007541				69	0	0.00	45	4	8.16
PIK3R1	0	genome.wustl.edu	37	5	67589537	67589537	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	5	67589537	67589537	G	A	SNP	PIK3R1	ENST00000396611	human	ensembl	74_37	+1	known	missense	c.1300	p.D434N	1.000	superfamily_Guanylate-bd_C,prints_PI3kinase_P85	pfam_SH2,pfam_RhoGAP_dom,pfam_SH3_2,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_Guanylate-bd_C,smart_SH3_domain,smart_RhoGAP_dom,smart_SH2,pfscan_SH2,pfscan_SH3_domain,pfscan_RhoGAP_dom,prints_PI3kinase_P85,prints_SH2	-	no_errors	PIK3R1	HGNC	ENSG00000145675	tier1	-	-	31	0	0.00	19	6	24.00
PODNL1	0	genome.wustl.edu	37	19	14044768	14044768	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	14044768	14044768	G	T	SNP	PODNL1	ENST00000339560	human	ensembl	74_37	-1	known	missense	c.711	p.S237R	1.000	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	PODNL1	HGNC	ENSG00000132000				61	0	0.00	36	4	10.00
PRNT	0	genome.wustl.edu	37	20	4713189	4713189	+	Missense_Mutation	SNP	G	G	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	20	4713189	4713189	G	C	SNP	PRNT	ENST00000326539	human	ensembl	74_37	-1	known	missense	c.134	p.T45R	0.000	NULL	NULL	-	no_errors	PRNT	HGNC	ENSG00000180259	tier1	-	-	89	0	0.00	125	8	6.02
PSG3	0	genome.wustl.edu	37	19	43228177	43228177	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	43228177	43228177	G	T	SNP	PSG3	ENST00000327495	human	ensembl	74_37	-1	known	missense	c.1244	p.A415D	0.296	NULL	pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	PSG3	HGNC	ENSG00000221826	tier1	-	-	57	0	0.00	31	16	34.04
PXDN	0	genome.wustl.edu	37	2	1677547	1677547	+	Missense_Mutation	SNP	A	A	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	2	1677547	1677547	A	C	SNP	PXDN	ENST00000252804	human	ensembl	74_37	-1	known	missense	c.886	p.L296V	0.617	pfam_Ig_I-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Haem_peroxidase_animal,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_VWF_C,pfam_Leu-rich_rpt,superfamily_Haem_peroxidase,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_VWF_C,prints_Haem_peroxidase_animal_subgr,pfscan_VWF_C,pfscan_Haem_peroxidase_animal,pfscan_Ig-like_dom	-	no_errors	PXDN	HGNC	ENSG00000130508	tier1	-	-	84	0	0.00	58	24	29.27
RAF1	0	genome.wustl.edu	37	3	12632438	12632438	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	12632438	12632438	C	T	SNP	RAF1	ENST00000442415	human	ensembl	74_37	-1	known	missense	c.1289	p.G430E	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Raf-like_ras-bd,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_Kinase-like_dom,smart_Raf-like_ras-bd,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Raf-like_ras-bd,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_DAG/PE-bd	-	no_errors	RAF1	HGNC	ENSG00000132155				65	0	0.00	64	4	5.88
RAI14	0	genome.wustl.edu	37	5	34823711	34823711	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	5	34823711	34823711	G	T	SNP	RAI14	ENST00000515799	human	ensembl	74_37	+1	known	missense	c.1773	p.E591D	1.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_t-SNARE,superfamily_UBA-like,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	RAI14	HGNC	ENSG00000039560				27	0	0.00	24	2	7.69
RNASEL	0	genome.wustl.edu	37	1	182550476	182550476	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	182550476	182550476	G	A	SNP	RNASEL	ENST00000367559	human	ensembl	74_37	-1	known	missense	c.1789	p.R597W	0.055	pfam_KEN_dom	pfam_Ankyrin_rpt,pfam_KEN_dom,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Ankyrin_rpt-contain_dom,superfamily_Kinase-like_dom,smart_Ankyrin_rpt,smart_Ser/Thr_dual-sp_kinase_dom,smart_PUG-dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom,prints_Ankyrin_rpt	-	no_errors	RNASEL	HGNC	ENSG00000135828	tier1	-	-	58	0	0.00	26	12	31.58
RPL41	0	genome.wustl.edu	37	12	56510561	56510561	+	RNA	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	56510561	56510561	A	G	SNP	RPL41	ENST00000358888	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.034	-	-	-	no_errors	RPL41	HGNC	ENSG00000229117	tier1	-	-	68	0	0.00	58	6	9.38
RPUSD2	0	genome.wustl.edu	37	15	40861777	40861777	+	Missense_Mutation	SNP	C	C	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	15	40861777	40861777	C	G	SNP	RPUSD2	ENST00000315616	human	ensembl	74_37	+1	known	missense	c.241	p.P81A	0.003	NULL	pfam_PsdUridine_synth_RsuA/RluD,superfamily_PsdUridine_synth_cat_dom,tigrfam_PsdUridine_synth_RluC/D	-	no_errors	RPUSD2	HGNC	ENSG00000166133	tier1	-	-	25	0	0.00	34	8	19.05
SCFD1	0	genome.wustl.edu	37	14	31107338	31107338	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	14	31107338	31107338	G	T	SNP	SCFD1	ENST00000458591	human	ensembl	74_37	+1	known	missense	c.320	p.R107L	1.000	pfam_Sec1-like,superfamily_Sec1-like	pfam_Sec1-like,superfamily_Sec1-like	-	no_errors	SCFD1	HGNC	ENSG00000092108				65	0	0.00	36	2	5.26
SGSM2	0	genome.wustl.edu	37	17	2266394	2266394	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	2266394	2266394	G	A	SNP	SGSM2	ENST00000268989	human	ensembl	74_37	+1	known	missense	c.638	p.R213H	0.988	NULL	pfam_Run,pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Run,smart_Rab-GTPase-TBC_dom,pfscan_Run,pfscan_Rab-GTPase-TBC_dom	-	no_errors	SGSM2	HGNC	ENSG00000141258	tier1	-	-	55	0	0.00	11	11	50.00
SIPA1L2	0	genome.wustl.edu	37	1	232650479	232650479	+	Silent	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	1	232650479	232650479	A	G	SNP	SIPA1L2	ENST00000262861	human	ensembl	74_37	-1	known	silent	c.607	p.L203	0.233	NULL	pfam_DUF3401,pfam_Rap_GAP_dom,pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ,pfscan_Rap_GAP_dom	-	no_errors	SIPA1L2	HGNC	ENSG00000116991				21	0	0.00	17	3	15.00
SLC35G5	0	genome.wustl.edu	37	8	11188922	11188922	+	Missense_Mutation	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	8	11188922	11188922	T	C	SNP	SLC35G5	ENST00000382435	human	ensembl	74_37	+1	known	missense	c.307	p.W103R	0.984	pfam_DMT	pfam_DMT	-	no_errors	SLC35G5	HGNC	ENSG00000177710	tier1	rs76944947	-	96	0	0.00	83	7	7.78
SMAD1	0	genome.wustl.edu	37	4	146435831	146435831	+	Silent	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	4	146435831	146435831	G	A	SNP	SMAD1	ENST00000302085	human	ensembl	74_37	+1	known	silent	c.66	p.Q22	1.000	superfamily_MAD_homology_MH1,pfscan_MAD_homology_MH1	pfam_SMAD_dom_Dwarfin-type,pfam_MAD_homology1_Dwarfin-type,pfam_Interferon_reg_factor-3,superfamily_SMAD_FHA_domain,superfamily_MAD_homology_MH1,smart_MAD_homology1_Dwarfin-type,smart_SMAD_dom_Dwarfin-type,pfscan_MAD_homology_MH1,pfscan_SMAD_dom_Dwarfin-type	-	no_errors	SMAD1	HGNC	ENSG00000170365	tier1	-	-	25	0	0.00	25	4	13.79
TAF4B	0	genome.wustl.edu	37	18	23915142	23915142	+	Missense_Mutation	SNP	C	C	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	18	23915142	23915142	C	A	SNP	TAF4B	ENST00000269142	human	ensembl	74_37	+1	known	missense	c.2263	p.R755S	1.000	pfam_TAF4	pfam_TAF4,pfam_TAFH_NHR1,superfamily_Histone-fold,smart_TAFH_NHR1,pfscan_TAFH_NHR1	-	no_errors	TAF4B	HGNC	ENSG00000141384				51	0	0.00	38	2	5.00
TGM4	0	genome.wustl.edu	37	3	44955211	44955211	+	Silent	SNP	C	C	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	44955211	44955211	C	G	SNP	TGM4	ENST00000296125	human	ensembl	74_37	+1	known	silent	c.2049	p.T683	0.605	pfam_Transglutaminase_C,superfamily_Transglutaminase_C	pfam_Transglutaminase_N,pfam_Transglutaminase_C,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like	-	no_errors	TGM4	HGNC	ENSG00000163810	tier1	-	-	58	0	0.00	35	4	10.26
THOC7	0	genome.wustl.edu	37	3	63823667	63823667	+	Silent	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	63823667	63823667	G	T	SNP	THOC7	ENST00000295899	human	ensembl	74_37	-1	known	silent	c.337	p.R113	1.000	pfam_THOC7/Mft1	pfam_THOC7/Mft1	-	no_errors	THOC7	HGNC	ENSG00000163634	tier1	-	-	58	0	0.00	19	10	34.48
TMEM132D	0	genome.wustl.edu	37	12	129569270	129569270	+	Missense_Mutation	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	12	129569270	129569270	A	G	SNP	TMEM132D	ENST00000389441	human	ensembl	74_37	-1	known	missense	c.35	p.L12P	0.000	NULL	NULL	-	no_errors	TMEM132D	HGNC	ENSG00000151952	tier1	-	-	48	0	0.00	36	4	9.76
TMEM239	0	genome.wustl.edu	37	20	2797573	2797573	+	Missense_Mutation	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	20	2797573	2797573	C	T	SNP	TMEM239	ENST00000554164	human	ensembl	74_37	+1	known	missense	c.644	p.P215L	1.000	NULL	NULL	-	no_errors	TMEM239	HGNC	ENSG00000198326	tier1	-	-	51	0	0.00	45	7	13.21
TMEM30C	0	genome.wustl.edu	37	3	99904605	99904605	+	Silent	SNP	C	C	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	3	99904605	99904605	C	T	SNP	TMEM30C	ENST00000429523	human	ensembl	74_37	+1	known	silent	c.75	p.I25	0.006	NULL	NULL	-	no_errors	TMEM30C	HGNC	ENSG00000235156	tier1	-	-	49	0	0.00	33	12	26.67
TMPRSS15	0	genome.wustl.edu	37	21	19685373	19685373	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	21	19685373	19685373	G	T	SNP	TMPRSS15	ENST00000284885	human	ensembl	74_37	-1	known	missense	c.2054	p.T685K	0.000	pfam_SRCR,superfamily_LDrepeatLR_classA_rpt,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel,pfscan_SRCR	pfam_Peptidase_S1,pfam_CUB_dom,pfam_MAM_dom,pfam_SEA_dom,pfam_LDrepeatLR_classA_rpt,pfam_Peptidase_S1A_nudel,pfam_SRCR,superfamily_Trypsin-like_Pept_dom,superfamily_ConA-like_lec_gl_sf,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,superfamily_Srcr_rcpt-rel,smart_SEA_dom,smart_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_MAM_dom,smart_Srcr_rcpt-rel,smart_Peptidase_S1,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_MAM_dom,pfscan_SEA_dom,pfscan_SRCR,pfscan_Peptidase_S1,prints_Peptidase_S1A,prints_LDrepeatLR_classA_rpt	-	no_errors	TMPRSS15	HGNC	ENSG00000154646				44	0	0.00	37	2	5.13
TP53	0	genome.wustl.edu	37	17	7577545	7577545	+	Missense_Mutation	SNP	T	T	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	17	7577545	7577545	T	C	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.736	p.M246V	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	271	0	0.00	107	101	48.56
TREML1	0	genome.wustl.edu	37	6	41119038	41119038	+	Missense_Mutation	SNP	G	G	T			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	6	41119038	41119038	G	T	SNP	TREML1	ENST00000426005	human	ensembl	74_37	-1	known	missense	c.461	p.P154H	0.258	NULL	pfam_Ig_V-set	-	no_errors	TREML1	HGNC	ENSG00000161911	tier1	-	-	99	0	0.00	56	20	26.32
USP18	0	genome.wustl.edu	37	22	18640567	18640567	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	22	18640567	18640567	G	A	SNP	USP18	ENST00000215794	human	ensembl	74_37	+1	known	missense	c.137	p.R46K	0.001	NULL	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	-	no_errors	USP18	HGNC	ENSG00000184979	tier1	-	-	38	0	0.00	29	8	21.62
VCL	0	genome.wustl.edu	37	10	75873970	75873970	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	75873970	75873970	G	A	SNP	VCL	ENST00000211998	human	ensembl	74_37	+1	known	missense	c.2978	p.R993H	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Vinculin	-	no_errors	VCL	HGNC	ENSG00000035403				35	0	0.00	17	2	10.53
XPNPEP1	0	genome.wustl.edu	37	10	111647946	111647946	+	Silent	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	10	111647946	111647946	A	G	SNP	XPNPEP1	ENST00000502935	human	ensembl	74_37	-1	known	silent	c.513	p.Y171	1.000	pfam_Creatinase	pfam_Pept_M24_structural-domain,pfam_Creatinase,superfamily_Pept_M24_structural-domain	-	no_errors	XPNPEP1	HGNC	ENSG00000108039				29	0	0.00	19	6	24.00
ZDHHC8P1	0	genome.wustl.edu	37	22	23734897	23734897	+	RNA	SNP	A	A	G			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	22	23734897	23734897	A	G	SNP	ZDHHC8P1	ENST00000456279	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.079	-	-	-	no_errors	ZDHHC8P1	HGNC	ENSG00000133519	tier1	-	-	55	0	0.00	31	15	32.61
ZNF185	0	genome.wustl.edu	37	X	152091293	152091293	+	Missense_Mutation	SNP	G	G	A			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	X	152091293	152091293	G	A	SNP	ZNF185	ENST00000370270	human	ensembl	74_37	+1	known	missense	c.767	p.R256Q	0.000	NULL	smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	ZNF185	HGNC	ENSG00000147394	tier1	-	-	45	0	0.00	41	21	33.87
ZNF701	0	genome.wustl.edu	37	19	53085583	53085583	+	Missense_Mutation	SNP	G	G	C			TCGA-L5-A4OQ-01A-11D-A27G-09	TCGA-L5-A4OQ-11A-12D-A27G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef228907-c929-4e96-b91e-016838b393da	deb263ba-4437-4d37-bde6-67d28cff9bf3	19	53085583	53085583	G	C	SNP	ZNF701	ENST00000301093	human	ensembl	74_37	+1	known	missense	c.469	p.E157Q	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF701	HGNC	ENSG00000167562	tier1	-	-	93	0	0.00	62	19	23.17