Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KRT17P2	339241	broad.mit.edu	37	17	18333127	18333127	+	RNA	SNP	G	G	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr17:18333127G>T	ENST00000326333.8	+	0	949																											GAGAAGAACCGCAAGGATGCC	0.592000													12	16					0.0931896	0.0953568	1	1	0
BTN2A3P	54718	broad.mit.edu	37	6	26422353	26422353	+	RNA	SNP	C	C	T	rs141013110		TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr6:26422353C>T	ENST00000466808.2	+	0	7																		p.P3S(2)									GCTCATGGAACCAGCTGCTGC	0.622000													4	90					0	0	1	0	0
CSF3	1440	broad.mit.edu	37	17	38172871	38172871	+	Missense_Mutation	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr17:38172871C>T	ENST00000331769.2	+	3	641	c.425C>T	c.(424-426)aCc>aTc	p.T142I	CSF3_ENST00000394149.3_Missense_Mutation_p.T146I|CSF3_ENST00000577675.1_Missense_Mutation_p.T106I|CSF3_ENST00000394148.3_Missense_Mutation_p.T113I|CSF3_ENST00000225474.2_Missense_Mutation_p.T149I			P09919	CSF3_HUMAN	colony stimulating factor 3 (granulocyte)	149					cytokine-mediated signaling pathway|granulocyte differentiation|immune response|positive regulation of cell proliferation	extracellular space	cytokine activity|enzyme binding|granulocyte colony-stimulating factor receptor binding|growth factor activity			endometrium(1)|ovary(1)|prostate(1)	3	Colorectal(19;0.000442)	Myeloproliferative disorder(1115;0.0255)			Filgrastim(DB00099)|Pegfilgrastim(DB00019)	TTTGCCACCACCATCTGGCAG	0.637000													50	56					0	0	1	0	0
ZMIZ2	83637	broad.mit.edu	37	7	44797153	44797153	+	Missense_Mutation	SNP	A	A	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr7:44797153A>G	ENST00000309315.4	+	5	668	c.545A>G	c.(544-546)tAt>tGt	p.Y182C	ZMIZ2_ENST00000433667.1_Missense_Mutation_p.Y150C|ZMIZ2_ENST00000265346.7_Missense_Mutation_p.Y182C|ZMIZ2_ENST00000413916.1_Missense_Mutation_p.Y150C|ZMIZ2_ENST00000441627.1_Missense_Mutation_p.Y182C	NM_031449.3	NP_113637.3	Q8NF64	ZMIZ2_HUMAN	zinc finger, MIZ-type containing 2	182					positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear replication fork	ligand-dependent nuclear receptor transcription coactivator activity|protein binding|zinc ion binding			breast(3)|endometrium(2)|kidney(3)|large_intestine(6)|lung(10)|ovary(6)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	35						CTGAGCCAGTATGGAGCGGTG	0.667000													7	8					0	0	1	0	0
PTOV1	53635	broad.mit.edu	37	19	50357743	50357743	+	Silent	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr19:50357743C>T	ENST00000391842.1	+	2	422	c.252C>T	c.(250-252)agC>agT	p.S84S	PTOV1_ENST00000601638.1_Silent_p.S52S|PTOV1_ENST00000600603.1_Silent_p.S52S|PTOV1_ENST00000599732.1_Silent_p.S84S|PTOV1_ENST00000221557.9_Silent_p.S52S|PTOV1_ENST00000601675.1_Silent_p.S84S|PTOV1_ENST00000598325.1_3'UTR|AC018766.6_ENST00000601211.1_RNA	NM_017432.3	NP_059128.2	Q86YD1	PTOV1_HUMAN	prostate tumor overexpressed 1	84					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus|perinuclear region of cytoplasm|plasma membrane				endometrium(5)|kidney(3)|large_intestine(2)|lung(5)|ovary(1)	16		all_lung(116;1.05e-05)|Lung NSC(112;3.77e-05)|all_neural(266;0.107)|Ovarian(192;0.231)		GBM - Glioblastoma multiforme(134;0.0116)|OV - Ovarian serous cystadenocarcinoma(262;0.0132)		TGGCCGTGAGCGAGCACCGGC	0.667000													4	108					0	0	1	0	0
TRANK1	9881	broad.mit.edu	37	3	36872529	36872529	+	Missense_Mutation	SNP	T	T	C			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr3:36872529T>C	ENST00000301807.6	-	21	8660	c.6763A>G	c.(6763-6765)Att>Gtt	p.I2255V	TRANK1_ENST00000429976.2_Missense_Mutation_p.I2805V|TRANK1_ENST00000428977.2_Missense_Mutation_p.I2255V			O15050	TRNK1_HUMAN	tetratricopeptide repeat and ankyrin repeat containing 1	2805					DNA repair		ATP binding|ATP-dependent DNA helicase activity|DNA binding			NS(2)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(20)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	73						CCTTCATCAATGGCCGGGTCC	0.532000													85	108					0	0	1	0	0
TBC1D9	23158	broad.mit.edu	37	4	141590905	141590905	+	Silent	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr4:141590905G>A	ENST00000442267.2	-	8	1394	c.1320C>T	c.(1318-1320)agC>agT	p.S440S		NM_015130.2	NP_055945.2	Q6ZT07	TBCD9_HUMAN	TBC1 domain family, member 9 (with GRAM domain)	440						intracellular	calcium ion binding|Rab GTPase activator activity			endometrium(3)|kidney(2)|large_intestine(3)|lung(18)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)	31	all_hematologic(180;0.162)	Medulloblastoma(177;0.00498)				CAGCATCAGAGCTCGTGCTTC	0.577000													17	25					0	0	1	0	0
FGFR3	2261	broad.mit.edu	37	4	1803568	1803568	+	Missense_Mutation	SNP	C	C	G	rs121913483		TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr4:1803568C>G	ENST00000340107.4	+	7	1002	c.746C>G	c.(745-747)tCc>tGc	p.S249C	FGFR3_ENST00000412135.2_Missense_Mutation_p.S249C|FGFR3_ENST00000474521.1_3'UTR|FGFR3_ENST00000481110.2_Missense_Mutation_p.S249C|FGFR3_ENST00000352904.1_Missense_Mutation_p.S249C|FGFR3_ENST00000440486.2_Missense_Mutation_p.S249C|FGFR3_ENST00000260795.2_Missense_Mutation_p.S249C	NM_001163213.1	NP_001156685.1	P22607	FGFR3_HUMAN	fibroblast growth factor receptor 3	249			S -> C (in KERSEB, bladder cancer, cervical cancer and TD1).		bone maturation|cell growth|insulin receptor signaling pathway|JAK-STAT cascade|MAPKKK cascade|negative regulation of developmental growth|positive regulation of cell proliferation	integral to plasma membrane	ATP binding|fibroblast growth factor binding|fibroblast growth factor receptor activity|identical protein binding	p.S249C(1204)|p.R248_S249del(1)		NS(1)|central_nervous_system(5)|cervix(6)|endometrium(2)|haematopoietic_and_lymphoid_tissue(40)|kidney(1)|large_intestine(5)|lung(9)|ovary(1)|pancreas(2)|prostate(9)|skin(339)|soft_tissue(4)|testis(2)|upper_aerodigestive_tract(58)|urinary_tract(2607)	3091		Breast(71;0.212)|all_epithelial(65;0.241)	all cancers(2;0.000145)|OV - Ovarian serous cystadenocarcinoma(23;0.0019)|Epithelial(3;0.00221)|GBM - Glioblastoma multiforme(2;0.234)		Palifermin(DB00039)	ACAGAGCGCTCCCCGCACCGG	0.736000		1	"""Mis, T"""	"""IGH@, ETV6"""	"""bladder, MM, T-cell lymphoma"""		"""Hypochondroplasia, Thanatophoric dysplasia"""		Saethre-Chotzen syndrome;Muenke syndrome				11	9					0	0	1	0	0
ANKRD36C	400986	broad.mit.edu	37	2	96593016	96593016	+	Missense_Mutation	SNP	C	C	A	rs79307257	by1000genomes	TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr2:96593016C>A	ENST00000456556.1	-	28	1969	c.1885G>T	c.(1885-1887)Gat>Tat	p.D629Y						ankyrin repeat domain 36C									p.D629Y(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						GAAACAGAATCTTTCTCATCA	0.318000													4	45					5.9392e-07	6.22202e-07	1	1	0
OLFM4	10562	broad.mit.edu	37	13	53624143	53624143	+	Missense_Mutation	SNP	C	C	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr13:53624143C>A	ENST00000219022.2	+	5	848	c.770C>A	c.(769-771)cCg>cAg	p.P257Q		NM_006418.4	NP_006409.3	Q6UX06	OLFM4_HUMAN	olfactomedin 4	257	Olfactomedin-like.				cell adhesion	extracellular space				breast(2)|endometrium(4)|kidney(4)|large_intestine(5)|lung(20)|skin(3)|urinary_tract(1)	39		Breast(56;0.000776)|Lung NSC(96;0.000814)|Hepatocellular(98;0.065)|Prostate(109;0.0771)|all_neural(104;0.173)		GBM - Glioblastoma multiforme(99;3.13e-08)		ATCAGCAAACCGTCTGTGGTT	0.433000													51	60					9.86064e-34	1.08467e-33	1	1	0
KIF23	9493	broad.mit.edu	37	15	69732743	69732743	+	Missense_Mutation	SNP	A	A	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr15:69732743A>G	ENST00000260363.4	+	17	2101	c.1984A>G	c.(1984-1986)Aaa>Gaa	p.K662E	KIF23_ENST00000395392.2_Missense_Mutation_p.K662E|KIF23_ENST00000558585.1_Missense_Mutation_p.K479E|KIF23_ENST00000537891.1_Missense_Mutation_p.K479E|KIF23_ENST00000352331.4_Missense_Mutation_p.K662E|KIF23_ENST00000559279.1_Missense_Mutation_p.K662E	NM_138555.2	NP_612565.1	Q02241	KIF23_HUMAN	kinesin family member 23	662					blood coagulation|cytokinesis|microtubule-based movement|mitosis|mitotic spindle elongation	cytosol|kinesin complex|microtubule|midbody|nucleoplasm|spindle	ATP binding|microtubule motor activity|protein binding			central_nervous_system(1)|endometrium(4)|large_intestine(7)|lung(6)|prostate(2)|skin(1)	21						TACCGAACCTAAAACTGAGAA	0.438000													38	29					0	0	1	0	0
SOGA1	140710	broad.mit.edu	37	20	35444501	35444501	+	Silent	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr20:35444501C>T	ENST00000237536.4	-	5	1685	c.1344G>A	c.(1342-1344)gtG>gtA	p.V448V	SOGA1_ENST00000456801.2_Silent_p.V51V|SOGA1_ENST00000279034.6_Silent_p.V210V|SOGA1_ENST00000357779.3_Silent_p.V210V	NM_080627.2	NP_542194.2	O94964	K0889_HUMAN	suppressor of glucose, autophagy associated 1	210										endometrium(5)|kidney(1)|lung(21)|urinary_tract(1)	28						GCTTCAGGTGCACCTTCAGCT	0.657000													13	20					0	0	1	0	0
KRT16P3	644945	broad.mit.edu	37	17	20405863	20405863	+	RNA	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr17:20405863G>A	ENST00000580113.1	-	0	1000																											GCCATTACTGGTGACTTGGGG	0.547000													12	40					0	0	1	0	0
KRTAP1-5	83895	broad.mit.edu	37	17	39183145	39183145	+	Missense_Mutation	SNP	A	A	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr17:39183145A>G	ENST00000361883.5	-	1	309	c.263T>C	c.(262-264)aTc>aCc	p.I88T		NM_031957.1	NP_114163.1	Q9BYS1	KRA15_HUMAN	keratin associated protein 1-5	88	15 X 5 AA repeats of C-C-[QEPVRC]- [TPIVLE]-[SRHVP].					keratin filament		p.I88T(11)		central_nervous_system(1)|endometrium(2)|kidney(1)|lung(9)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(2)	17		Breast(137;0.00043)	STAD - Stomach adenocarcinoma(17;0.000371)			GCAGGAGCTGATCTGGCAGCA	0.632000													6	59					0	0	1	0	0
LARP1	23367	broad.mit.edu	37	5	154174850	154174850	+	Missense_Mutation	SNP	C	C	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr5:154174850C>G	ENST00000336314.4	+	8	1141	c.1117C>G	c.(1117-1119)Ctt>Gtt	p.L373V		NM_015315.3	NP_056130.2	Q6PKG0	LARP1_HUMAN	La ribonucleoprotein domain family, member 1	450							protein binding|RNA binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(10)|lung(9)|ovary(3)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	33	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.147)	KIRC - Kidney renal clear cell carcinoma(527;0.00112)			AGTGCAGGCCCTTACCACTGA	0.517000													10	27					0	0	1	0	0
DNAH17	8632	broad.mit.edu	37	17	76475640	76475640	+	Silent	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr17:76475640C>T	ENST00000389840.5	-	50	7909	c.7785G>A	c.(7783-7785)acG>acA	p.T2595T	DNAH17_ENST00000586052.1_5'UTR|DNAH17_ENST00000585328.1_Silent_p.T2604T					dynein, axonemal, heavy chain 17											NS(2)|breast(7)|central_nervous_system(5)|cervix(1)|endometrium(15)|haematopoietic_and_lymphoid_tissue(1)|kidney(13)|large_intestine(8)|lung(37)|ovary(8)|prostate(7)|skin(4)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(3)	116			BRCA - Breast invasive adenocarcinoma(99;0.00294)|OV - Ovarian serous cystadenocarcinoma(97;0.0656)			CCAGGTGCTGCGTCAGGATTG	0.607000													30	38					0	0	1	0	0
PPL	5493	broad.mit.edu	37	16	4933452	4933452	+	Missense_Mutation	SNP	T	T	C			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr16:4933452T>C	ENST00000345988.2	-	22	5293	c.5204A>G	c.(5203-5205)tAt>tGt	p.Y1735C	PPL_ENST00000590782.2_Missense_Mutation_p.Y1733C	NM_002705.4	NP_002696	O60437	PEPL_HUMAN	periplakin	1735					keratinization	cytoskeleton|desmosome|mitochondrion|nucleus	protein binding|structural constituent of cytoskeleton			breast(6)|central_nervous_system(1)|endometrium(11)|kidney(5)|large_intestine(12)|lung(12)|ovary(4)|prostate(5)|skin(3)|stomach(1)|urinary_tract(2)	62						ATAGCGGTCATACTGAGCAGG	0.552000													19	30					0	0	1	0	0
NELL1	4745	broad.mit.edu	37	11	21594801	21594801	+	Missense_Mutation	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr11:21594801G>A	ENST00000298925.5	+	20	2465	c.2312G>A	c.(2311-2313)gGg>gAg	p.G771E	NELL1_ENST00000532434.1_Missense_Mutation_p.G696E|NELL1_ENST00000357134.5_Missense_Mutation_p.G743E|NELL1_ENST00000325319.5_Missense_Mutation_p.G686E|NELL1_ENST00000529218.1_3'UTR			Q92832	NELL1_HUMAN	NEL-like 1 (chicken)	743	VWFC 5.				cell adhesion|nervous system development	extracellular region	calcium ion binding|structural molecule activity			NS(1)|breast(3)|endometrium(5)|kidney(3)|large_intestine(15)|lung(36)|ovary(2)|prostate(3)|skin(1)|urinary_tract(1)	70						ATCTTAGAAGGGGAATGTTGT	0.473000													29	43					0	0	1	0	0
VTCN1	79679	broad.mit.edu	37	1	117695792	117695792	+	Silent	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr1:117695792G>A	ENST00000369458.3	-	4	723	c.645C>T	c.(643-645)taC>taT	p.Y215Y	VTCN1_ENST00000359008.4_Silent_p.Y218Y|VTCN1_ENST00000539893.1_Silent_p.Y120Y|VTCN1_ENST00000328189.3_Silent_p.Y99Y	NM_024626.3	NP_078902.2	Q7Z7D3	VTCN1_HUMAN	V-set domain containing T cell activation inhibitor 1	215	Ig-like V-type 2.					integral to membrane|plasma membrane				large_intestine(7)|lung(4)|upper_aerodigestive_tract(1)	12	Lung SC(450;0.225)	all_cancers(81;6.05e-06)|all_epithelial(167;5.59e-07)|all_lung(203;2.85e-06)|Lung NSC(69;2e-05)		Lung(183;0.0664)|LUSC - Lung squamous cell carcinoma(189;0.214)|Colorectal(144;0.23)		TCGTAACATTGTAGAGCACAG	0.453000													67	78					0	0	1	0	0
EIF2S1	1965	broad.mit.edu	37	14	67848360	67848360	+	Missense_Mutation	SNP	G	G	C			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr14:67848360G>C	ENST00000256383.4	+	6	1092	c.631G>C	c.(631-633)Gcc>Ccc	p.A211P	EIF2S1_ENST00000466499.2_Missense_Mutation_p.A211P	NM_004094.4	NP_004085.1	P05198	IF2A_HUMAN	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	211						cytosol|eukaryotic translation initiation factor 2 complex|polysome|stress granule	protein binding|ribosome binding|translation initiation factor activity			breast(1)|cervix(2)|endometrium(1)|large_intestine(1)|lung(2)|ovary(1)|upper_aerodigestive_tract(1)	9				all cancers(60;0.000683)|OV - Ovarian serous cystadenocarcinoma(108;0.00579)|BRCA - Breast invasive adenocarcinoma(234;0.00937)		TGTAAAAGAAGCCCTAAGAGC	0.348000													31	43					0	0	1	0	0
TRIM24	8805	broad.mit.edu	37	7	138239673	138239673	+	Missense_Mutation	SNP	A	A	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr7:138239673A>G	ENST00000343526.4	+	9	1707	c.1492A>G	c.(1492-1494)Atg>Gtg	p.M498V	TRIM24_ENST00000415680.2_Intron|TRIM24_ENST00000497516.1_Intron			O15164	TIF1A_HUMAN	tripartite motif containing 24	498					cellular response to estrogen stimulus|protein catabolic process|regulation of apoptosis|regulation of protein stability|transcription from RNA polymerase II promoter	cytoplasm	chromatin binding|estrogen response element binding|histone acetyl-lysine binding|p53 binding|transcription coactivator activity|ubiquitin-protein ligase activity|zinc ion binding			breast(2)|central_nervous_system(5)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(12)|ovary(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)	40						AAACCCTAGAATGCAGGGGCC	0.488000													42	41					0	0	1	0	0
ANKRD36C	400986	broad.mit.edu	37	2	96593000	96593000	+	Missense_Mutation	SNP	A	A	G	rs111976783		TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr2:96593000A>G	ENST00000456556.1	-	28	1985	c.1901T>C	c.(1900-1902)aTa>aCa	p.I634T						ankyrin repeat domain 36C									p.I634T(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						TTCTGTGGCTATATTTGAAAC	0.338000													3	45					0	0	1	0	0
CUL7	9820	broad.mit.edu	37	6	43019173	43019173	+	Missense_Mutation	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr6:43019173G>A	ENST00000535468.1	-	4	1104	c.1018C>T	c.(1018-1020)Cgg>Tgg	p.R340W	CUL7_ENST00000265348.3_Missense_Mutation_p.R256W	NM_001168370.1|NM_014780.4	NP_001161842.1|NP_055595.2	Q14999	CUL7_HUMAN	cullin 7	256					interspecies interaction between organisms|ubiquitin-dependent protein catabolic process|vasculogenesis	anaphase-promoting complex|mitochondrion	ubiquitin protein ligase binding			breast(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(8)|liver(1)|lung(11)|ovary(3)|prostate(2)|skin(3)|stomach(1)|urinary_tract(1)	49			all cancers(41;0.00231)|Colorectal(64;0.00237)|COAD - Colon adenocarcinoma(64;0.00473)|OV - Ovarian serous cystadenocarcinoma(102;0.0442)|KIRC - Kidney renal clear cell carcinoma(15;0.133)|Kidney(15;0.188)			TGCAAATACCGCTTCACCAGG	0.567000													17	38					0	0	1	0	0
MIR518D	574489	broad.mit.edu	37	19	54238195	54238195	+	RNA	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr19:54238195C>T	ENST00000385014.1	+	0	65					NR_030211.1																						AAGCGCTTCCCTTTGGAGCGT	0.443000													40	46					0	0	1	0	0
COL14A1	7373	broad.mit.edu	37	8	121237452	121237452	+	Splice_Site	SNP	C	C	T	rs145708206	byFrequency	TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr8:121237452C>T	ENST00000297848.3	+	15	2133	c.1863C>T	c.(1861-1863)acC>acT	p.T621T	COL14A1_ENST00000247781.3_Splice_Site_p.T526T|COL14A1_ENST00000309791.4_Splice_Site_p.T621T|COL14A1_ENST00000537875.1_3'UTR|COL14A1_ENST00000432943.2_3'UTR	NM_021110.1	NP_066933.1	Q05707	COEA1_HUMAN	collagen, type XIV, alpha 1	621	Fibronectin type-III 4.				cell-cell adhesion|collagen fibril organization	collagen type XIV|extracellular space	collagen binding|extracellular matrix structural constituent|protein binding, bridging			NS(1)|autonomic_ganglia(1)|breast(11)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(9)|large_intestine(31)|lung(42)|ovary(5)|pancreas(1)|prostate(1)|skin(8)|stomach(2)|upper_aerodigestive_tract(2)	119	Lung NSC(37;6.52e-07)|Ovarian(258;0.00769)|Hepatocellular(40;0.161)		OV - Ovarian serous cystadenocarcinoma(1;6.47e-38)|STAD - Stomach adenocarcinoma(47;0.00503)			TTTTTACCACCGGTAAGCAGC	0.403000													31	56					0	0	1	0	0
DBN1	1627	broad.mit.edu	37	5	176887532	176887532	+	Silent	SNP	G	G	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr5:176887532G>T	ENST00000292385.5	-	11	1471	c.862C>A	c.(862-864)Cgg>Agg	p.R288R	DBN1_ENST00000393563.4_Silent_p.R18R|DBN1_ENST00000393565.1_Silent_p.R286R|DBN1_ENST00000512501.1_Silent_p.R18R|DBN1_ENST00000309007.5_Silent_p.R286R	NM_080881.2	NP_543157	Q16643	DREB_HUMAN	drebrin 1	286					actin filament organization|regulation of dendrite development|regulation of neuronal synaptic plasticity	actomyosin|cytoplasm|dendrite	actin binding|profilin binding			breast(3)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(1)|lung(12)|ovary(1)|skin(2)	25	all_cancers(89;2.17e-05)|Renal(175;0.000269)|Lung NSC(126;0.0014)|all_lung(126;0.0025)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			TTGTCAGGCCGCTGGGCAATA	0.612000													58	71					7.50695e-29	8.05624e-29	1	1	0
JAG2	3714	broad.mit.edu	37	14	105609073	105609073	+	Missense_Mutation	SNP	C	C	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr14:105609073C>A	ENST00000331782.3	-	26	4079	c.3676G>T	c.(3676-3678)Gtc>Ttc	p.V1226F	JAG2_ENST00000347004.2_Missense_Mutation_p.V1188F	NM_002226.4	NP_002217.3	Q9Y219	JAG2_HUMAN	jagged 2	1226					auditory receptor cell fate commitment|cell communication|cell cycle|Notch receptor processing|Notch signaling pathway|regulation of cell migration|regulation of cell proliferation|spermatogenesis|thymic T cell selection	integral to plasma membrane	calcium ion binding|growth factor activity|Notch binding			breast(2)|endometrium(2)|kidney(3)|large_intestine(1)|lung(7)|prostate(2)|skin(5)	22		all_cancers(154;0.0336)|all_epithelial(191;0.0729)|Melanoma(154;0.155)	OV - Ovarian serous cystadenocarcinoma(23;0.00989)|all cancers(16;0.0114)|Epithelial(46;0.0272)	Epithelial(152;0.047)|OV - Ovarian serous cystadenocarcinoma(161;0.148)|all cancers(159;0.208)		ATGCTCCTGACCGCGCGGTTG	0.692000													3	17					1	1	1	1	0
KLHDC2	23588	broad.mit.edu	37	14	50249092	50249092	+	Nonsense_Mutation	SNP	T	T	G			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr14:50249092T>G	ENST00000557247.1	+	10	1189	c.888T>G	c.(886-888)taT>taG	p.Y296*	KLHDC2_ENST00000298307.5_Missense_Mutation_p.W321G|KLHDC2_ENST00000554589.1_Missense_Mutation_p.W321G			Q9Y2U9	KLDC2_HUMAN	kelch domain containing 2	0						nucleus	protein binding			endometrium(3)|large_intestine(3)|lung(5)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	16	all_epithelial(31;0.000959)|Breast(41;0.0117)					ATGCAGGTTATGGCACACAGC	0.413000													31	53					0	0	1	0	0
SIK2	23235	broad.mit.edu	37	11	111591410	111591410	+	Silent	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr11:111591410G>A	ENST00000304987.3	+	11	1877	c.1704G>A	c.(1702-1704)caG>caA	p.Q568Q		NM_015191.1	NP_056006.1	Q9H0K1	SIK2_HUMAN	salt-inducible kinase 2	568					intracellular protein kinase cascade|regulation of insulin receptor signaling pathway	Golgi apparatus	ATP binding|magnesium ion binding|protein binding|protein serine/threonine kinase activity			breast(1)|central_nervous_system(2)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(5)|lung(7)|prostate(3)|skin(1)|upper_aerodigestive_tract(3)	30						TGAGCTCCCAGAAACGAGAGG	0.547000													27	50					0	0	1	0	0
POLE	5426	broad.mit.edu	37	12	133218864	133218864	+	Missense_Mutation	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr12:133218864C>T	ENST00000320574.5	-	38	5115	c.5072G>A	c.(5071-5073)cGc>cAc	p.R1691H	POLE_ENST00000535270.1_Missense_Mutation_p.R1664H	NM_006231.2	NP_006222.2	Q07864	DPOE1_HUMAN	polymerase (DNA directed), epsilon, catalytic subunit	1691					base-excision repair, gap-filling|DNA synthesis involved in DNA repair|DNA-dependent DNA replication initiation|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|nucleotide-excision repair, DNA gap filling|S phase of mitotic cell cycle|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	nucleoplasm	chromatin binding|DNA binding|DNA-directed DNA polymerase activity|nucleotide binding|protein binding|zinc ion binding			NS(2)|autonomic_ganglia(1)|breast(5)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(16)|lung(41)|ovary(3)|pancreas(2)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)	89	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.0416)		OV - Ovarian serous cystadenocarcinoma(86;5.22e-08)|Epithelial(86;4.03e-07)|all cancers(50;1.18e-05)		CAGGTCAGGGCGGGCTGTAGG	0.572000								DNA polymerases (catalytic subunits)					32	46					0	0	1	0	0
TMEM8C	389827	broad.mit.edu	37	9	136384092	136384092	+	Silent	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr9:136384092G>A	ENST00000339996.3	-	3	404	c.303C>T	c.(301-303)gtC>gtT	p.V101V	TMEM8C_ENST00000413714.1_5'UTR	NM_001080483.2	NP_001073952.1	A6NI61	TMM8C_HUMAN	transmembrane protein 8C	101						integral to membrane				NS(1)|autonomic_ganglia(1)|large_intestine(2)|lung(4)	8						CAATGGTCAGGACGCCGAACA	0.607000													47	74					0	0	1	0	0
CEACAM3	1084	broad.mit.edu	37	19	42301736	42301736	+	Missense_Mutation	SNP	G	G	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr19:42301736G>A	ENST00000357396.3	+	2	521	c.280G>A	c.(280-282)Gca>Aca	p.A94T	CEACAM3_ENST00000221999.4_Missense_Mutation_p.A94T|CEACAM3_ENST00000595255.1_3'UTR|CEACAM3_ENST00000344550.4_Missense_Mutation_p.A94T	NM_001815.2	NP_001806.2	P40198	CEAM3_HUMAN	carcinoembryonic antigen-related cell adhesion molecule 3	94	Ig-like V-type.					integral to membrane		p.A94T(1)		endometrium(2)|kidney(4)|large_intestine(1)|lung(4)|prostate(3)|skin(4)|stomach(1)	19						CCCAGGGGCCGCATACAGCGG	0.463000													4	225					0	0	1	0	0
P2RX3	5024	broad.mit.edu	37	11	57114033	57114033	+	Silent	SNP	C	C	T			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr11:57114033C>T	ENST00000263314.2	+	2	169	c.135C>T	c.(133-135)caC>caT	p.H45H		NM_002559.3	NP_002550.2	P56373	P2RX3_HUMAN	purinergic receptor P2X, ligand-gated ion channel, 3	45					positive regulation of calcium ion transport into cytosol|positive regulation of calcium-mediated signaling	integral to plasma membrane	ATP binding|extracellular ATP-gated cation channel activity|purinergic nucleotide receptor activity	p.H45H(1)		endometrium(4)|kidney(2)|large_intestine(4)|lung(15)|prostate(1)	26						TTTTCTTGCACGAGAAGGCTT	0.547000													3	58					0	0	1	0	0
AC079779.6	0	broad.mit.edu	37	2	322068	322068	+	RNA	DEL	G	G	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr2:322068delG	ENST00000436808.2	+	0	11																											tggggcaggtggggaggagca	0.527													2	4	---	---	---	---					
APOB	338	broad.mit.edu	37	2	21260839	21260840	+	Frame_Shift_Ins	INS	-	-	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr2:21260839_21260840insA	ENST00000233242.1	-	5	654_655	c.527_528insT	c.(526-528)gtgfs	p.V176fs	APOB_ENST00000399256.4_Frame_Shift_Ins_p.V176fs	NM_000384.2	NP_000375	P04114	APOB_HUMAN	apolipoprotein B	176	Vitellogenin.				cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			NS(5)|autonomic_ganglia(1)|breast(6)|central_nervous_system(4)|cervix(3)|endometrium(19)|kidney(10)|large_intestine(63)|liver(5)|lung(125)|ovary(16)|pancreas(1)|prostate(5)|skin(31)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(6)	305	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	CCAGAAACAACACTTGCTTGGC	0.460													60	91	---	---	---	---					
UGT1A1	54658	broad.mit.edu	37	2	234622156	234622158	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr2:234622156_234622158delGAG	ENST00000608381.1	+	1	519_521	c.519_521delGAG	c.(517-522)ttgagg>ttg	p.R174del	UGT1A6_ENST00000373424.1_Intron|UGT1A1_ENST00000373450.4_Intron|UGT1A10_ENST00000344644.5_Intron|UGT1A10_ENST00000373445.1_Intron|UGT1A5_ENST00000373414.3_In_Frame_Del_p.R174del|UGT1A6_ENST00000406651.1_Intron|UGT1A9_ENST00000354728.4_Intron|UGT1A7_ENST00000373426.3_Intron|UGT1A6_ENST00000305139.6_Intron|UGT1A1_ENST00000609637.1_Intron|UGT1A6_ENST00000480628.1_Intron	NM_019078.1	NP_061951.1	P22309	UD11_HUMAN							bilirubin conjugation|digestion|estrogen metabolic process|flavone metabolic process|heme catabolic process	endoplasmic reticulum membrane|microsome	enzyme binding|enzyme inhibitor activity|glucuronosyltransferase activity|protein heterodimerization activity|protein homodimerization activity|retinoic acid binding|steroid binding			breast(1)|central_nervous_system(2)|endometrium(7)|large_intestine(5)|lung(9)|skin(4)|urinary_tract(2)	30		Breast(86;0.000766)|all_lung(227;0.00271)|Renal(207;0.00339)|all_hematologic(139;0.0116)|Acute lymphoblastic leukemia(138;0.0326)|Lung NSC(271;0.0461)|Lung SC(224;0.128)		Epithelial(121;4.1e-18)|BRCA - Breast invasive adenocarcinoma(100;0.000435)|Lung(119;0.00211)|LUSC - Lung squamous cell carcinoma(224;0.0054)	Abacavir(DB01048)|Adenine(DB00173)|Diclofenac(DB00586)|Estradiol(DB00783)|Ezetimibe(DB00973)|Irinotecan(DB00762)|Mycophenolate mofetil(DB00688)|Mycophenolic acid(DB01024)|Propofol(DB00818)|Rifampin(DB01045)|Troglitazone(DB00197)	TGTTTTTCTTGAGGAACATTCCA	0.463													94	163	---	---	---	---					
RSPH4A	345895	broad.mit.edu	37	6	116950757	116950758	+	Frame_Shift_Ins	INS	-	-	A			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr6:116950757_116950758insA	ENST00000229554.5	+	4	1827_1828	c.1690_1691insA	c.(1690-1692)caafs	p.Q564fs	RSPH4A_ENST00000368581.4_Intron|RSPH4A_ENST00000368580.4_Frame_Shift_Ins_p.Q317fs	NM_001010892.2	NP_001010892.1	Q5TD94	RSH4A_HUMAN	radial spoke head 4 homolog A (Chlamydomonas)	564	Glu-rich.				cilium axoneme assembly|cilium movement	cytoplasm|cytoskeleton|radial spoke				breast(1)|endometrium(2)|kidney(1)|large_intestine(11)|lung(8)|pancreas(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	27						CAACTCCATACAAAAAAATgag	0.371									Kartagener syndrome				50	71	---	---	---	---					
CNTNAP3B	728577	broad.mit.edu	37	9	43844265	43844265	+	Frame_Shift_Del	DEL	G	G	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr9:43844265delG	ENST00000377564.3	+	10	1992	c.1599delG	c.(1597-1599)gcgfs	p.A533fs		NM_001201380.1	NP_001188309.1	Q96NU0	CNT3B_HUMAN	contactin associated protein-like 3B	533	Laminin G-like 2.				cell adhesion|signal transduction	integral to membrane	receptor binding			central_nervous_system(1)|endometrium(2)|lung(3)|pancreas(1)|prostate(3)	10						AGCAGGGGGCGCTGGGGAGTT	0.542													4	5	---	---	---	---					
SNORD56	26793	broad.mit.edu	37	11	89851593	89851593	+	RNA	DEL	T	T	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr11:89851593delT	ENST00000384569.1	+	0	35																											TCGACAGCAGTTCACCCATTG	0.448													2	4	---	---	---	---					
IREB2	3658	broad.mit.edu	37	15	78783054	78783054	+	Frame_Shift_Del	DEL	G	G	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr15:78783054delG	ENST00000258886.8	+	18	2424	c.2275delG	c.(2275-2277)ggafs	p.G759fs		NM_004136.2	NP_004127	P48200	IREB2_HUMAN	iron-responsive element binding protein 2	759							4 iron, 4 sulfur cluster binding|metal ion binding|protein binding			central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(8)|liver(1)|lung(14)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	41				UCEC - Uterine corpus endometrioid carcinoma (272;0.232)		ATCACCTGCAGGAAGTATCGC	0.398													117	122	---	---	---	---					
RRN3P2	653390	broad.mit.edu	37	16	29113498	29113498	+	RNA	DEL	T	T	-	rs11366120		TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr16:29113498delT	ENST00000564580.1	+	0	1360																											AGGAGGTGGAttttttttttc	0.542													6	5	---	---	---	---					
GLTSCR1	29998	broad.mit.edu	37	19	48198717	48198717	+	Frame_Shift_Del	DEL	C	C	-			TCGA-CF-A9FM-01A-11D-A38G-08	TCGA-CF-A9FM-10A-01D-A38J-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bd8aed9e-9a24-4bfa-9b02-0e11e31ed01b	4bc4c1f2-3570-48cc-a509-38e80aa09cd4	g.chr19:48198717delC	ENST00000396720.3	+	10	3366	c.3172delC	c.(3172-3174)cccfs	p.P1058fs	CTD-2571L23.8_ENST00000599924.1_lincRNA	NM_015711.3	NP_056526.3	Q9NZM4	GSCR1_HUMAN	glioma tumor suppressor candidate region gene 1	1058							protein binding			breast(2)|endometrium(1)|kidney(1)|large_intestine(4)|lung(3)|pancreas(3)|prostate(4)|skin(2)	20		all_cancers(25;1.8e-07)|all_lung(116;5.73e-06)|Lung NSC(112;9.69e-06)|all_epithelial(76;2.42e-05)|all_neural(266;0.0332)|Ovarian(192;0.086)		all cancers(93;0.000358)|OV - Ovarian serous cystadenocarcinoma(262;0.000576)|Epithelial(262;0.0212)|GBM - Glioblastoma multiforme(486;0.0355)		GCCAGGGAAGCCCTCCGGGCT	0.657													2	4	---	---	---	---