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Effects of ONC201 on mantle cell lymphoma cell lines

样本量:28 物种:Homo sapiens 类型:transcription profiling by array 2016年2月20日

...TP53 inactivation) or acquired resistance to other agents. Because the mechanism of action in these malignant hematologi...

Large genomic alteration of 7q in two patients with multiple primary cancers,...

样本量:8 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2016年2月15日

...TP53 genes and large genomic rearrangements mapped on chromosome 7q. Genomic rearrangements were assessed with Affymetri...

Genomic and Transcriptomic Hallmarks of Poorly-Differentiated and Anaplastic ...

样本量:37 物种:Homo sapiens 类型:transcription profiling by array 2016年2月15日

...TP53, TERT promoter, PI3K/AKT/mTOR pathway effectors, SWI/SNF subunits and histone methyltransferases. BRAF and RAS are ...

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal S...

样本量:172 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2016年2月12日

...TP53, and fluorescence in situ hybridization. Comparative genomic hybridization (aCGH) of CAS revealed a copy-neutral di...

The MYC-MIZ1 interaction defines tumor identity

样本量:23 物种:Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2016年1月21日

...TP53 mutations and G3 MBs characterized by C-MYC (MYC) overexpression in ~17% of cases from gene amplification with stem...

Expression changes following combined treatment with RG7388 + GSK2830371

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2016年1月20日

...TP53 wild-type cells. NGP cells were treated for 4 hours with 0.5% DMSO (solvent control), RG7388 (75nM) + GSK2830371 (2...

Targeting the lineage-specific long non-coding RNA LINC01212 as an effective ...

样本量:9 物种:Homo sapiens 类型:transcription profiling by array 2016年1月15日

...TP53 status, diminishes melanoma growth and increases their sensitivity to MAPK-targeting therapeutics both in vitro and...

Subtelomeric p53 Binding Prevents Accumulation of DNA Damage at Human Telomer...

样本量:5 物种:Homo sapiens 类型:ChIP-seq 2016年1月7日

...TP53 (p53) function in genome protection, but a direct role of p53 at telomeres has not yet been described. Here, we ha...

Renal Cell Carcinomas in Vinylidene Chloride Exposed Male B63FC1 Mice Are Cha...

样本量:18 物种:Mus musculus 类型:transcription profiling by array 2015年12月21日

...Tp53 cell cycle checkpoint and DNA damage repair pathways. Trend analysis comparing RCC, VDC-exposed kidney, and vehicle...

Epigenetic regulation of the homeobox gene MSX1 associates with platinum resi...

样本量:86 物种:Homo sapiens 类型:methylation profiling by array 2015年11月26日

...TP53 expressing ovarian cancer cell lines, resistant to cisplatin, have reduced MSX1 expression compared to matched pare...

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