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CRISPR screen exploring resistance to AKTi (Capivasertib) in ER+ Breast Cance...

样本量:19 物种:Homo sapiens, Homo sapiens 类型:genotyping by high throughput sequencing 2026年5月25日

...cancer cell lines T47D, MCF7, and CAMA-1 to identify genes modulating sensitivity and resistance to capivasertib, a sele...

Single-cell DNA sequencing analysis of ecDNA copy-number dynamics during drug...

样本量:10 物种:Homo sapiens, Homo sapiens 类型:DNA-seq 2026年5月25日

...cancer cell lines, single-cell-derived clones, and drug-treated conditions. Droplet-based targeted PCR amplification was...

RNA-seq of human breast cancer cell line MCF7, T47D and CAMA-1 treated that a...

样本量:74 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA 2026年5月25日

MCF7, T47D and CAMA-1 cell lines were treated with long-term (continuous) capivasertib to induce resistant cell-lines (T...

Runx1 and Runx2 act in concert to suppress Wnt/b-catenin-driven mammary tumou...

样本量:19 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2026年5月1日

The genes for transcription factor RUNX1 and its binding partner CBFb have been reported to be mutated in human breast c...

Transcriptomic profiling of genetically engineered mouse tumors using SOCRATE...

样本量:1 物种:Mus musculus, Mus musculus, Mus musculus 类型:RNA-seq of coding RNA from single cel... 2026年5月1日

...cancer, including Apc, Kras, Trp53, Smad4, and Pten. Following tumor formation, tissues were dissociated and processed ...

Single-cell RNA-sequencing of colorectal cancer PDOX tumors treated with vehi...

样本量:4 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA from single cel... 2026年4月29日

...cancer organoids were injected into mice to grow into subcutaneous tumors. Starting at 100 mm3, tumors were treated with...

Molecular insights into DDX3X–mRNA regulation in castration-resistant prostat...

样本量:8 物种:Homo sapiens, Homo sapiens 类型:RIP-seq 2026年4月17日

...Cancer Progression (BCaP) cell lines were used for RIP-seq. Input and RIP RNA from the androgen receptor low/negative ca...

ATAC-seq to investigate rewiring the transcriptome of castration-resistant pr...

样本量:8 物种:Homo sapiens, Homo sapiens 类型:ATAC-seq 2026年4月8日

...cancer and a targetable vulnerability for treating metastatic cancers. CDK9, whose primary function is to promote transc...

RNA-Seq analysis of subcutaneous patient-derived neuroblastoma xenografts (LU...

样本量:21 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA 2026年4月1日

...cancer characterized by significant heterogeneity and poor prognosis, particularly in high-risk cases with MYCN amplific...

Binding of full length p73 (TAp73alpha) and cancer-specific variant (DNp73bet...

样本量:12 物种:Homo sapiens, Homo sapiens 类型: 2026年3月30日

All p73 isoforms share an identical DNA-binding domain. These CUT&RUN datasets for TAp73α, DNp73β, and a GFP control ill...

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