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Exome data: Clonal evolution of longitudinally sampled triple negative breast...

样本量:16 物种:Homo sapiens, Homo sapiens 类型:DNA-seq 2023年8月9日

...TP53, BRAF & CSF3R (Patient 04) and ESR1, APC, EZH2 & TP53 (Patient 07). Such branching evolution is seen in all three p...

Illumina Microarray of T47D cell with or without KDM7A-DT silencing under nor...

样本量:24 物种:Homo sapiens, Homo sapiens 类型:transcription profiling by array 2023年5月1日

...TP53-dependency upon oxidative and oncogenic stress induction. Since about 50% of human breast cancers have mutant p53 a...

Illumina Microarray of MRC5 cell with or without KDM7A-DT overexpression

样本量:8 物种:Homo sapiens, Homo sapiens 类型:transcription profiling by array 2023年5月1日

...TP53-dependency upon oxidative and oncogenic stress induction. To investigate the functional roles of KDM7A-DT, we first...

Multiomics of three distinct hematological malignancies in a patient reveals ...

样本量:39 物种:Homo sapiens, Homo sapiens 类型:spatial transcriptomics by high-throu... 2023年3月17日

...TP53 and LYN deleterious mutations, DLBCL-NOS disclosed KRAS, STAT6, CREBBP and ATM alterations and AML-M5 had JAK3, PPM...

CNV data:Clonal evolution of longitudinally sampled triple negative breast ca...

样本量:11 物种:Homo sapiens, Homo sapiens 类型:genotyping by array 2022年12月30日

...TP53, BRAF & CSF3R (Patient 04) and ESR1, APC, EZH2 & TP53 (Patient 07). Such branching evolution is seen in all three p...

Molecular characterisation of TP53 mutated squamous cell carcinomas of the lu...

样本量:209 物种:Homo sapiens, Homo sapiens 类型:Human - One-color microarray, transcr... 2020年5月22日

Patients undergoing surgery for squamous cell carcinomas of the lung were included, a total of 188 tumours and 21 matche...

TP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rha...

样本量:10 物种:Mus musculus 类型:transcription profiling by array 2019年12月31日

...TP53 axis plays a critical role in regulating proteostasis and an increased demand for protein disposal.

Genetic dynamics in untreated chronic lymphocytic leukemia patients with eith...

样本量:52 物种:Homo sapiens 类型:genotyping by array 2019年11月5日

...TP53, XPO1 and ZMYM3, which were previously identified as mutated in CLL studies.

Microarray analysis of MDA-MB231 cell treated with the p53-reactivating molec...

样本量:16 物种:Homo sapiens 类型:transcription profiling by array 2019年9月20日

...TP53 inactivating mutations, frequently found in human tumors, could interfere with Granzyme B-mediated cell death, the ...

Transcription profiling by array of 5-Aza-2’-deoxycytidine treated gastric ca...

样本量:12 物种:Homo sapiens 类型:transcription profiling by array 2019年4月30日

...TP53 loss of copy. Moreover, ACP03 is able to start a tumorigenesis process in Cebus apellas.

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