Single-cell RNA-seq of PBMCs from HCC patients pre- and post-curative therapy

·发布 2026年1月13日

样本数

实验数

相关文献

实验描述

This dataset contains processed single-cell RNA sequencing (scRNA-seq) data from peripheral blood mononuclear cells (PBMCs) collected from six hepatocellular carcinoma (HCC) patients, before and after curative therapy. Samples were profiled using the 10x Genomics Chromium platform. The dataset includes gene expression matrices and associated metadata for 12 samples (6 pre-therapy, 6 post-therapy). These data support the analysis of peripheral immune cell dynamics in response to tumor removal

参考文献

A monocyte-derived blood transcriptomic signature reveals systemic immunosuppression in HCC and partial reversal following curative therapy.

Zhou L, Alaswad A, Kumthekar A, Machtens D, Xi Y, Costa B, Xu CJ, Wirth T, Li Y.

PMID: 41646974

样本属性

Organism

Homo sapiens

Organism part

blood

Cell type

PBMC

Disease

hepatocellular carcinoma

Sex

male, female, male, male, male, male, male, female, male

Age

69, 62, 57, 80,65,62, 65,73, ... 2 other values

Developmental stage

pre, post,pre, pre, post,post, pre, pre, ... 2 other values

Individual

HCC1,HCC2,HCC6, HCC2,HCC3,HCC4, HCC3,HCC5, ... 2 other values

实验信息

登记号

E-MTAB-16408

实验类型

RNA-seq of coding RNA from single cells

物种

Homo sapiens, Homo sapiens

发布日期

2026年1月13日

提交者

Liang Zhou

外部链接

ArrayExpress 原始页

分析服务

Single-cell RNA-seq of PBMCs from HCC patients pre- and post-curative therapy

联系地址

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