Circulating microRNA expression data of the caloric restriction applied breast cancer mouse model

A chronic or intermittent caloric restriction protocol was applied to mice from 10 weeks of age up to 82 weeks of age. Blood samples were collected at weeks 10 (baseline), 49/50 (adult), and old (81/82). Total RNA was isolated, and circulating miRNA profiling was performed using the Affymetrix GeneChip 4.1 miRNA microarray platform. Bioinformatic analyses were performed to identify age- and diet-associated circulating miRNAs in a lifelong CCR- or ICR-applied tumor-free breast cancer mouse model.